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Structural Comparison of Natural and Synthetic Nanocrystalline Hydroxyapatite



Foroughi MR1 ; Tabrizi BN1 ; Karbasi S2 ; Kahrizsangi RE1
Authors
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Authors Affiliations
  1. 1. Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Isfahan, Iran
  2. 2. Department of Medical Physics and Biomedical Engineering, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2012

Abstract

Background: Hydroxyapatite is the main mineral component of bones. Due to its high biocompatibility, it is widely used in the treatment of bone lesions or production of dental or orthopedic implants. Biological behavior of hydroxyapatite depends on many factors such as chemical composition and phase, microstructure, size, and porosity volume. On the other hand, other hydroxyapatite nanocrystals have received increased attention due to their improved bio-efficiency including connectivity and formation of new bones on their surface. Methods: In this research, nanocrystalline hydroxyapatite powder was synthesized by thermal synthesis or mechanochemical methods. The structures of the two types were then compared. Findings: Products obtained from both processes was single-phase hydroxyapatite. No other stable phases were detected. Degrees of crystalline of the products of thermal synthesis and mechanochemical methods were 92.86% and 6.72%, respectively. Most particles had quasi-spherical morphology. In addition, particle sizes of products of heating and mechanochemical methods were 85 and 58 nm, respectively. Conclusion: Phase analysis showed that the product of both processes was single-phase hydroxyapatite. On the other hand, all characteristic peaks were present in the product and it had high purity. © 2018, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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