Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Solvent-Free Synthesis, Adme Prediction, and Evaluation of Antibacterial Activity of Novel Sulfonamide Derivatives Publisher



Rafiee Pour Z1 ; Nazifi SMR2 ; Afshari Safavi A3 ; Nazifi ZS1 ; Massah AR1, 4
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Chemistry, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, Iran
  2. 2. Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Student Research Committee, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Razi Chemistry Research Center, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, Iran

Source: Russian Journal of Organic Chemistry Published:2019


Abstract

A series of novel sulfonamides containing a 2-amino-1,3-thiazole fragment have been synthesized using a simple and efficient method under solvent-free conditions. The obtained N-(4-sulfamoyl-1,3-thiazol-2-yl)-4-nitrobenzamides were evaluated for their antibacterial activity against S. aureus and E. coli, and in silico ADME prediction was performed to find biological behavior. © 2019, Pleiades Publishing, Ltd.
Related Docs
View other Related Docs
1. Synthesis, Molecular Docking Studies, and Absorption, Distribution, Metabolism, and Excretion Prediction of Novel Sulfonamide Derivatives As Antibacterial Agents, Journal of the Chinese Chemical Society (2019)
2. Synthesis of Some Novel Coumarin Isoxazol Sulfonamide Hybrid Compounds, 3D-Qsar Studies, and Antibacterial Evaluation, Scientific Reports (2021)
3. Convenient Synthesis of Novel Chalcone and Pyrazoline Sulfonamide Derivatives As Potential Antibacterial Agents, Russian Journal of Bioorganic Chemistry (2020)
4. Synthesis and Cytotoxic Evaluation of Some Novel Sulfonamide Derivatives Against a Few Human Cancer Cells, Iranian Journal of Pharmaceutical Research (2011)
5. Synthesis, Characterization and in Vitro Antibacterial Activity of Novel Phthalazine Sulfonamide Derivatives, Journal of Chemical Sciences (2017)
6. Synthesis, and Molecular Docking Studies of Novel 1,2,3-Triazoles-Linked Pyrazole Carboxamides As Significant Anti-Microbial and Anti-Cancer Agents, Results in Chemistry (2024)
7. New 3-Hydroxypyridine-4-One Analogues: Their Synthesis, Antimicrobial Evaluation, Molecular Docking, and in Silico Adme Prediction, Medicinal Chemistry (2024)
8. Synthesis, Antimicrobial Evaluation, Molecular Docking, and Adme Studies of Some Novel 3-Hydroxypyridine-4-One Derivatives, ChemistrySelect (2023)
Experts (# of related papers)
View all Related Experts
Farshid Hassanzadeh (7)
Lotfollah Saghaie Dehkordi (5)
Other Related Docs
9. Synthesis of Novel Conjugated Benzofuran-Triazine Derivatives: Antimicrobial and In-Silico Molecular Docking Studies, Heliyon (2023)
10. Docking Study, Synthesis and Antimicrobial Evaluation of Some Novel 4-Anilinoquinazoline Derivatives, Research in Pharmaceutical Sciences (2017)
11. Biologically Active Heterocyclic Hybrids Based on Quinazolinone, Benzofuran and Imidazolium Moieties: Synthesis, Characterization, Cytotoxic and Antibacterial Evaluation, Chemistry and Biodiversity (2017)
12. Design, Synthesis and Biological Activity of Hybrid Antifungals Derived From Fluconazole and Mebendazole, European Journal of Medicinal Chemistry (2023)
13. Novel N-Α-Amino Acid Spacer-Conjugated Phthalimide–Triazine Derivatives: Synthesis, Antimicrobial and Molecular Docking Studies, Amino Acids (2023)
14. Synthesis, Qsar Modeling, and Molecular Docking Studies of 1,2,3-Triazole-Pyrazole Hybrids As Significant Anti-Cancer and Anti-Microbial Agents, Journal of Molecular Structure (2025)
15. Synthesis of Some Benzothiazole Derivatives Based on 3-Hydroxypyridine-4-One and Benzaldehyde and Evaluation of Their Β-Amyloid Aggregation Inhibition Using Both Experimental Methods and Molecular Dynamic Simulation, Chemistry and Biodiversity (2023)
16. Synthesis, Antimicrobial Evaluation and Docking Studies of Some Novel Quinazolinone Schiff Base Derivatives, Research in Pharmaceutical Sciences (2018)
17. Synthesis, Biological and Docking Studies of Thiadiazole Amide Derivatives Containing Anthranilic Acid, Journal of Sciences, Islamic Republic of Iran (2023)
18. Investigation of Biological Effects of New Tetrazole Compounds on Cancer Cell Lines (Hela, Mcf-7) and Common Microorganisms (Staphylococcus Aureus, Escherichia Coli, Candida Albicans), Journal of Isfahan Medical School (2023)
19. Synthesis and Evaluation of Thiadiazole-Based Antileishmanial Agents, Journal of Reports in Pharmaceutical Sciences (2020)
20. Synthesis, Characterization, Molecular Docking Studies and Biological Evaluation of Some Novel Hybrids Based on Quinazolinone, Benzofuran and Imidazolium Moieties As Potential Cytotoxic and Antimicrobial Agents, Iranian Journal of Basic Medical Sciences (2017)