Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Study of Aqueous and Alcoholic Extract of the Melissa Officinalis Effect on Candida Albicans, Candida Glabrata and Candida Krusei



Taheri JB1, 2 ; Iman M3 ; Mehdipour M2 ; Bakhtiari S2 ; Namazi F4 ; Bayan MT1, 2 ; Zeinali N5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Preventative Dentistry Research Center, Research Institute of Dental Sciences, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Chemical Injuries Research Center, System Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
  4. 4. Department of Nuclear Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran
  5. 5. Pharmaceutical Biotechnology Department, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Military Medicine Published:2017

Abstract

Background and Aim: Fungal infections, especially candida species, are the most common opportunistic fungal infections and the treatments with chemical drugs have many side effects. Melissa Officinalis has antimicrobial effects that has caused it to be considered in many microbial treatments. In this study, it has been tried to compare this herbal efficacy on Candida Albicans, Candida Glabrata and Candida Krusei. Methods: Aqueous and ethanol extracts of Melissa Officinalis was obtained by drench method. The diameter of non- growing zone of Candida Albicans, Candida Glabrata and Candida Krusei was estimated by the micro dilution method. Results: The mean diameter of the non-growing zone related to the extracts on Candida Albicans was 17.83 mm (versing 5.75 mm of aqueous extracts) and the mean diameter of the non-growing zone related to aqueous extracts on Candida Glabrata and Candida Krusei were 15.5 and 13.66 mm respectively (versing 10 and 7mm of ethanolic extracts). Conclusion: All extracts had an effect on non- growing fungal zone, however ethanolic extract of Candida Albicans and aqueous extract of Candida Krusei were more effective rather than the others. Also, there was no difference between the effect of Aqueous and ethanolic extracts in Candida Glabrata.
Related Docs
View other Related Docs
1. Antifungal Activity of Zingiber Officinale Rosc. Essential Oil Against Fluconazole Resistant Vaginal Isolates of Candida Albicans, Journal of Medicinal Plants (2007)
2. Synergistic Activity Between Echinophora Platyloba Dc Ethanolic Extract and Azole Drugs Against Clinical Isolates of Candida Albicans From Women Suffering Chronic Recurrent Vaginitis, Journal de Mycologie Medicale (2014)
3. Antifungal Susceptibility Testing of Candida Species Isolated From the Immunocompromised Patients Admitted to Ten University Hospitals in Iran: Comparison of Colonizing and Infecting Isolates, BMC Infectious Diseases (2017)
4. Heart Palpitation Relief With Melissa Officinalis Leaf Extract: Double Blind, Randomized, Placebo Controlled Trial of Efficacy and Safety, Journal of Ethnopharmacology (2015)
5. Multicenter Identification and Antifungal Susceptibility Patterns of Candida Species Isolated From Clinical Samples, Jundishapur Journal of Microbiology (2017)
6. The Effects of Nutraceuticals and Herbal Medicine on Candida Albicans in Oral Candidiasis: A Comprehensive Review, Advances in Experimental Medicine and Biology (2021)
7. Antifungal Activity of Almond (Prunus Amygdalus) Hull Extracts Against Clinical Isolates of Candida Albicans, Current Medical Mycology (2024)
8. Evaluation and Comparison of Antifungal Effect of Voriconazole With Nystatin on Candida Species Derived From Neoplastic Patients Undergoing Maxillofacial Radiotherapy, Dental Research Journal (2023)
Experts (# of related papers)
View all Related Experts
Rasoul Mohammadi (20)
Parvin Dehghan (17)
Other Related Docs
9. A Survey on Microbial Quality of Herbal Distillates in Isfahan, Central of Iran, Studia Universitatis Vasile Goldis Arad, Seria Stiintele Vietii (2014)
10. Overview on the Infections Related to Rare Candida Species, Pathogens (2022)
11. Antifungal Activity of Myrtus Communis L. Esssential Oil Against Clinical Isolates of Aspergillus, Journal of Isfahan Medical School (2008)
12. Species Distribution and Susceptibility Profiles of Oral Candidiasis in Hematological Malignancy and Solid Tumor Patients, Brazilian Journal of Microbiology (2023)
13. Antifungal Activity of Anethum Graveolens Extract and Atrovastatin Against Candida Species Compared to Fluconazole, Journal of Isfahan Medical School (2015)
14. Antifungal Effect of Atorvastatin Against Candida Species in Comparison to Fluconazole and Nystatin, Medicine and Pharmacy Reports (2019)
15. Identification and Frequency of Candida Species in Patients With Different Forms of Candidiasis in Isfahan, Using Pcr-Rflp Method, Journal of Isfahan Medical School (2011)
16. Evaluation of the Effects of Photodynamic Therapy With Methylene Blue on Different Candida Species in Vitro, Journal of Lasers in Medical Sciences (2023)
17. Chemical Composition and Antibacterial Activities of Sumac Fruit (Rhus Coriaria) Essential Oil on Dental Caries Pathogens, Open Microbiology Journal (2020)
18. A Review of the Antifungal Properties of Medicinal Herbs, Journal of Isfahan Medical School (2015)
19. In Vitro Activities of Six Antifungal Drugs Against Candida Glabrata Isolates: An Emerging Pathogen, Jundishapur Journal of Microbiology (2016)
20. The Evaluation of the Overexpression of the Erg-11, Mdr-1, Cdr-1, and Cdr-2 Genes in Fluconazole-Resistant Candida Albicans Isolated From Ahvazian Cancer Patients With Oral Candidiasis, Journal of Clinical Laboratory Analysis (2022)
21. The Frequency of Oral Candidiasis in Children and Adolescents With Leukemia in Isfahan Province, Iran, Journal of Isfahan Medical School (2017)
22. Bioassay-Guided Isolation in Salvia Abrotanoides Karel. Stem Based on Its Anti-Fungal and Anti-Trichomonas Activity, Research in Pharmaceutical Sciences (2023)
23. Evaluation of the Antifungal Effect of Fluconazole Separately and With Coriander Essential Oil on Candida Species Isolated From the Mouth of Hiv-Positive Individuals, Scientific Journal of Kurdistan University of Medical Sciences (2023)
24. Identification of Candida Species Isolated From Candiduria Patients Using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism in Isfahan, Iran, Journal of Isfahan Medical School (2016)
25. Epidemiology and Antifungal Susceptibility of Candida Species Isolated From 10 Tertiary Care Hospitals in Iran, Microbiology Spectrum (2022)
26. Antifungal Activity of Cinnamomum Zeylanicum Essential Oil Against Clinical Isolates of Aspegillus, Journal of Medicinal Plants (2010)
27. Antifungal Activity of Ferula Assa- Foetida Against Clinical Agents of Mucormycosis, Journal of Isfahan Medical School (2009)
28. The Matching Rate of the Frequency of the Isolated Candida Species Calculated by Morphological and Molecular Methods in Patients With Vaginitis, Journal of Isfahan Medical School (2017)
29. The Antibacterial Activity of Nasturtium Officinale Extract on Common Oral Pathogenic Bacteria, Nigerian Journal of Clinical Practice (2022)
30. Epidemiologic and Antifungal Susceptibility Profile of Candiduria Among Patients Hospitalized in the Nephrology and Intensive Care Unit Wards, Tehran, Iran, Jundishapur Journal of Microbiology (2022)
31. Caspofungin-Non-Susceptible Candida Orthopsilosis Isolated From Onychomycosis in Iran, Iranian Journal of Public Health (2017)
32. Anti Candidal Activity of Echinophora Platyloba Against Candida Albicans and Comparison With Amphotricin, Journal of Medicinal Plants (2009)
33. Candida Africana Vulvovaginitis: Prevalence and Geographical Distribution, Journal de Mycologie Medicale (2020)
34. Microbial Epidemiology of Candidaemia in Neonatal and Paediatric Intensive Care Units at the Children's Medical Center, Tehran, Mycoses (2018)
35. Candida Palmioleophila Candidemia and Bacterial Co-Infection in a 3-Month-Old Infant With Biliary Atresia, Frontiers in Cellular and Infection Microbiology (2023)
36. The Frequency of Candiduria in Hospitalized Patients at Nephrology Department, Labbafinejad Hospital, Tehran, Iran, Journal of Isfahan Medical School (2017)
37. Evaluation of the Therapeutic Effect of 15 Ppm Silver Nanoparticle Spray Compared to Clotrimazole 1% on Candida Vaginitis: A Randomized Controlled Clinical Trial, Journal of Family and Reproductive Health (2023)
38. Identification of Candida Species and Antifungal Susceptibility in Cancer Patients With Oral Lesions in Ahvaz, Southern West of Iran, Advanced Biomedical Research (2020)
39. In Vitro Antifungal Susceptibility Pattern of Candida Species Isolated From Gastroesophageal Candidiasis, Gastroenterology and Hepatology from Bed to Bench (2021)
40. Molecular Identification of Candida Species Isolated From Gastrooesophageal Candidiasis in Tehran, Iran, Gastroenterology and Hepatology from Bed to Bench (2015)
41. Comparative Evaluation of Ketoconazole Tablet and Topical Ketoconazole 2% in Orabase in Treatment of Candida-Infected Denture Stomatitis, Journal of Contemporary Dental Practice (2010)
42. Cross-Sectional Study of Candidemia From Isfahan, Iran: Etiologic Agents, Predisposing Factors, and Antifungal Susceptibility Testing, Journal of Research in Medical Sciences (2021)
43. Frequency of Candida Species Isolated From Patients in Children’S Medical Center, Tehran, Iran, Archives of Pediatric Infectious Diseases (2018)
44. Species Distribution and Antifungal Susceptibility Profile of Candida Isolates From Blood and Other Normally Sterile Foci From Pediatric Icu Patients in Tehran, Iran, Medical Mycology (2020)
45. Protective Effect of Melissa Officinalis Extract Against H2o2-Induced Oxidative Stress in Human Vascular Endothelial Cells, Research in Pharmaceutical Sciences (2016)
46. Epidemiology, Species Distribution, Antifungal Susceptibility, and Outcome of Candidemia in Intensive Care Units in Isfahan, Iran, Current Medical Mycology (2022)
47. Frequency of Candida Species Isolated From the Oral Cavity of Hiv-Infected Patients Referring to Behavioral Disease Counseling Center of Isfahan in 2017-2018, Scientific Journal of Kurdistan University of Medical Sciences (2019)
48. Candida Urinary Tract Infection Among Icu Patients in Isfahan, Iran, Archives of Clinical Infectious Diseases (2019)
49. Identification of Candida Species in Oral Cavity of Smokers and Nonsmokers, Journal of Isfahan Medical School (2016)
50. Antifungal Effect of Echinophora Platyloba Essence Against the Candida Species Isolated From Vulvovaginal Candidiasis, Compared With Fluconazole, Journal of Isfahan Medical School (2014)