Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Characteristics of Pre-Diabetic Patients Associated With Body Composition and Cardiovascular Disease Risk Factors in the Iranian Population Publisher



Gholi Z1 ; Heidaribeni M2 ; Feizi A3 ; Iraj B4 ; Askari G1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Community Nutrition, Food Security Research Center, School of Nutrition and Food Sciences, Iran
  2. 2. Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Iran
  3. 3. Department of Biostatistics and Epidemiology, Isfahan Endocrine and Metabolism Research Center, School of Health, Iran
  4. 4. Department of Internal Medicine and Endocrinology, Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Research in Medical Sciences Published:2016


Abstract

Background: Different populations have shown various patterns of association between impaired fasting glucose (IFG) and body composition parameters and risk factors of cardiovascular disease (CVD). The current study aimed at investigating the differences between persons with prediabetes and healthy people in terms of CVD risk factors including body composition parameters, blood pressure, and lipid profile in a sample of the Iranian population. Materials and Methods: In a case-control setting, a sample containing 386 (193 prediabetic subjects and 193 normal subjects) of the first-degree relatives of diabetic patients aged 35-55 years were investigated. Samples were assessed using glucose tolerance categories. Prediabetes was defined according to the American Diabetes Association (ADA) criteria. Body composition parameters, blood pressure, glucose parameters, and lipid profile were measured and compared between the two groups. Results: Prediabetic patients had higher body mass index (BMI), waist circumference (WC), and body fat (BF) in comparison to the control group (P < 0.05). In addition, prediabetic subject had a higher intake of energy, carbohydrate, protein, fat, and cholesterol and it seems that these patients had an unhealthy dietary intake (P < 0.05). Fasting blood glucose (FBG) (P < 0.001), total cholesterol (P = 0.007), low-density lipoprotein cholesterol (LDL-C), and triglyceride (P = 0.021) were higher in prediabetic patients (P < 0.05) than in the controls. Conclusion: Both the risk factors of CVD and body composition parameters were different between the prediabetic and normal groups; total cholesterol (TC), triglyceride (TG), and FBS were predictors of the risk of prediabetes. © 2016 Journal of Research in Medical Sciences.
Related Docs
View other Related Docs
1. Healthy and Unhealthy Dietary Patterns Are Related to Pre-Diabetes: A Case-Control Study, British Journal of Nutrition (2016)
2. Prevalence and Risk Factors of Diabetes Mellitus in the Isfahan City Population (Aged 40 or Over) in 1993, Diabetes Research and Clinical Practice (1997)
3. Factors Associated With Progression to Pre-Diabetes: A Recurrent Events Analysis, Eating and Weight Disorders (2020)
4. Should the First Degree Relatives of Type 2 Diabetic Patients With Isolated Impaired Fasting Glucose Be Considered for a Diabetes Primary Prevention Program?, Journal of Research in Medical Sciences (2010)
5. People With Impaired Glucose Tolerance and Impaired Fasting Glucose Are Similarly Susceptible to Cardiovascular Disease: A Study in First-Degree Relatives of Type 2 Diabetic Patients, Annals of Nutrition and Metabolism (2010)
6. Serum Uric Acid Level and Its Association With Cardiometabolic Risk Factors in Prediabetic Subjects, Journal of Research in Medical Sciences (2014)
7. Anthropometric Indices Predicting Incident Type 2 Diabetes in an Iranian Population: The Isfahan Cohort Study, Diabetes and Metabolism (2013)
8. The Prevalence of Cardiovascular Risk Factors in Patients With Type 1 Diabetes in Isfahan, Iran, Iranian Journal of Diabetes and Lipid Disorders (2007)
Experts (# of related papers)
View all Related Experts
Nizal Sarrafzadegan (122)
Roya Kelishadi (116)
Other Related Docs
9. Pre-Diabetes and Cardiovascular Risk Factors in Nafld Patients: A Retrospective Comparative Analysis, Frontiers in Endocrinology (2025)
10. Metabolic Syndrome in Iranian Elderly, ARYA Atherosclerosis (2012)
11. The Changes in Cardiovascular Disease Risk Factors After the Implementation of the Package of Essential Non-Communicable Disease Control, Journal of Cardiovascular and Thoracic Research (2024)
12. The Effect of Nutrition Education on Risk Factors of Cardiovascular Diseases in Elderly Patients With Type 2 Diabetes: A Randomized Controlled Trial, Iranian Journal of Endocrinology and Metabolism (2011)
13. Diabetes and Impaired Glucose Regulation in First-Degree Relatives of Patients With Type 2 Diabetes in Isfahan, Iran: Prevalence and Risk Factors, Review of Diabetic Studies (2007)
14. Prevalence and Risk Factors of Diabetes, Pre-Diabetes and Metabolic Syndrome in First-Degree Relatives of Patients With Type Ii Diabetes, Journal of Kerman University of Medical Sciences (2013)
15. Clustering of Coronary Artery Disease Risk Factors in Patients With Type 2 Diabetes and Impaired Glucose Tolerance, Eastern Mediterranean Health Journal (2008)
16. Dietary Insulin Index and Load and Cardiometabolic Risk Factors Among People With Obesity: A Cross-Sectional Study, BMC Endocrine Disorders (2023)
17. Comparison of Metabolic Syndrome With Glucose Measurement for Prediction of Type 2 Diabetes: The Isfahan Diabetes Prevention Study, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2009)
18. Cardiovascular Risk Factors in Relatives of Type 2 Diabetics With Normal Glucose Tolerance Test and Elevated One-Hour Plasma Glucose, Endokrynologia Polska (2010)
19. Normalization of Glucose Intolerance in First-Degree Relatives of Patients With Type 2 Diabetes, Diabetes Research and Clinical Practice (2010)
20. Utility of Hypertriglyceridemic Waist Phenotype for Predicting Incident Type 2 Diabetes: The Isfahan Diabetes Prevention Study, Journal of Diabetes Investigation (2016)
21. Metabolic Syndrome in Type 2 Diabetes Mellitus in Isfahan, Iran: Prevalence and Risk Factors, Metabolic Syndrome and Related Disorders (2007)
22. How Is Healthy Eating Index-2015 Related to Risk Factors for Cardiovascular Disease in Patients With Type 2 Diabetes, Frontiers in Nutrition (2023)
23. High Blood Pressure and Associated Cardiovascular Risk Factors in Iran: Isfahan Healthy Heart Programme, Medical Journal of Malaysia (2004)
24. Comparison of Glycated Hemoglobin With Fasting Plasma Glucose in Definition of Glycemic Component of the Metabolic Syndrome in an Iranian Population, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2012)
25. The Relationship Between Social Factors and Blood Glucose Control in Patients With Type Ii Diabetes in Isfahan Township, Iran, Journal of Isfahan Medical School (2017)
26. Food Intake Patterns May Explain the High Prevalence of Cardiovascular Risk Factors Among Iranian Women, Journal of Nutrition (2008)
27. Evaluation of Changes in Blood Sugar Levels in a 14-Years Cohort Study of Pre-Diabetic Patients and Its Relation With Diabetes, Tehran University Medical Journal (2021)
28. Association Between Alternative Healthy Eating Index (Ahei) With Metabolic Health Status in Adolescents With Overweight and Obesity, BMC Public Health (2024)
29. Association Between Dietary Insulin Index and Load With Obesity in Adults, European Journal of Nutrition (2020)
30. Evaluation of the Effects of Dietary Energy Density on Anthropometric and Glycemic Indices and Lipid Profile in Women With Type 2 Diabetes Mellitus, Journal of Isfahan Medical School (2012)
31. Effects of Gender and Height on the Oral Glucose Tolerance Test: The Isfahan Diabetes Prevention Study, Review of Diabetic Studies (2008)
32. Consumption of Energy-Dense Diets in Relation to Cardiometabolic Abnormalities Among Iranian Women, Public Health Nutrition (2012)
33. Association of Quality and Quantity of Macronutrients Intake With Obesity, New Anthropometric Indices, Lipid Accumulation, and Blood Lipid Risk Index in Tehranian Women, Food Science and Nutrition (2024)
34. Diabetes and Associated Cardiovascular Risk Factors in Iran: The Isfahan Healthy Heart Programme, Annals of the Academy of Medicine Singapore (2007)
35. Impact of Diabesity Phenotype on Cardiovascular Diseases, Major Cardiovascular Events and All-Cause Mortality, Scientific Reports (2023)
36. Association Between Type 2 Diabetes and Different Types of Dietary Fats: A Case-Control Study, Clinical Nutrition ESPEN (2023)
37. Association of Glycaemic Index and Glycaemic Load With Metabolic Syndrome in an Iranian Adult Population: Isfahan Healthy Heart Program, Nutrition and Dietetics (2017)
38. Low-Carbohydrate-Diet Score and Metabolic Syndrome: An Epidemiologic Study Among Iranian Women, Nutrition (2015)
39. Hypertension in Type 2 Diabetes Mellitus in Isfahan, Iran: Incidence and Risk Factors, Diabetes Research and Clinical Practice (2005)
40. The Effects of Macronutrient Intake on the Risk of Pre-Diabetes in First- Degree Relatives of Patients With Type 2 Diabetes, Journal of Isfahan Medical School (2014)
41. Adherence to Lifelines Diet Score and Risk Factors of Metabolic Syndrome Among Overweight and Obese Adults: A Cross-Sectional Study, Frontiers in Nutrition (2022)
42. Comparison of Body Mass Index With Abdominal Obesity Indicators and Waist-To-Stature Ratio for Prediction of Type 2 Diabetes: The Isfahan Diabetes Prevention Study, Obesity Research and Clinical Practice (2010)
43. Effect of Potato Consumption As a High Glycemic Index Food on Pre-Diabetes Adult Patients, Pakistan Journal of Medical Sciences (2013)
44. Determinants of Incident Prediabetes and Type 2 Diabetes in a 7-Year Cohort in a Developing Country: The Isfahan Cohort Study, Journal of Diabetes (2015)
45. Variations in Diabetes Prevalence in Low-, Middle-, and High-Income Countries: Results From the Prospective Urban and Rural Epidemiological Study, Diabetes Care (2016)
46. Progression to Impaired Glucose Metabolism in First-Degree Relatives of Patients With Type 2 Diabetes in Isfahan, Iran, Diabetes/Metabolism Research and Reviews (2009)
47. The Visceral Adiposity Index in Comparison With Easily Measurable Anthropometric Markers Did Not Improve Prediction of Diabetes, Canadian Journal of Diabetes (2016)
48. The Product of Triglycerides and Glucose in Comparison With Fasting Plasma Glucose Did Not Improve Diabetes Prediction, Acta Diabetologica (2015)
49. Dietary Glycemic Index and Insulin Index in Association With Incident Type 2 Diabetes Mellitus in Adults, British Journal of Nutrition (2025)
50. The Prevalence of Impaired Fasting Glucose and Type 2 Diabetes in a Population-Based Sample of Overweight/Obese Children in the Middle East, Pediatric Diabetes (2010)