Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Is There a Relationship Between 24-Hour Urinary Sodium and Potassium and Mental Health in Migraine Patients?: A Cross-Sectional Study Publisher Pubmed

Summary: Study finds higher dietary sodium and sodium-to-potassium ratio linked to lower depression, anxiety, and stress in migraine patients, suggesting dietary impacts on mental health. #MentalHealth #Migraine

Arab A1 ; Zabibah RS2 ; Alshahrani SH3 ; Karimi E4, 5 ; Askari G1 ; Khorvash F6
Authors

Source: Medicine (United States) Published:2022


Abstract

There is a lack of evidence and consensus in terms of the association between dietary intake of sodium (Na) and potassium (K) with mental health. By using 24-hours urinary samples as the gold standard method, we conducted a study to explore the association between dietary intake of Na and K with parameters of mental health including depression, anxiety, and stress among an Iranian population diagnosed with migraine. In the present study, 262 subjects (20-50 years old), with a confirmed diagnosis of migraine were enrolled. Mental health was investigated by the Depression, Anxiety, and Stress Scales (DASS-21) questionnaire. Dietary intake of Na and K was estimated by means of a 24-hour urine sample. Multinomial logistic regression analysis was implemented and odds ratio (OR) with 95% confidence interval (CI) was stated. After controlling for potential confounders, the 24-hour urinary Na was associated significantly with the risk of depression (OR=0.55, 95% CI: 0.30, 1.00; P=.053). After adjustment for confounders, those in the highest tertile of the 24-hour urinary Na/K ratio had lower odds for having depression (OR=0.54, 95% CI: 0.31, 0.93; P=.027), and marginally significantly lower risk of anxiety (OR=0.58, 95% CI: 0.31, 1.06; P=.079) and stress (OR=0.56, 95% CI: 0.31, 1.02; P=.061). In conclusion, higher 24-hour urine Na was associated with a significantly lower risk of depression. Moreover, the 24-hour Na/K ratio was significantly associated with lower risk of depression, anxiety, and stress. © 2022 Lippincott Williams and Wilkins. All rights reserved.
Related Docs
View other Related Docs
1. Is There a Relationship Between Dietary Sodium and Potassium Intake and Clinical Findings of a Migraine Headache?, British Journal of Nutrition (2022)
2. Empirically Derived Dietary Patterns and Their Association With Mental Health: A Cross-Sectional Sample of Iranian Migraine Patients (2019–2020), BMC Nutrition (2022)
3. Plant-Based Eating Pattern and Psychological Symptoms: A Cross-Sectional Survey Among Patients With Migraine, Nutritional Neuroscience (2025)
Experts (# of related papers)
View all Related Experts
Gholamreza Askari (14)
Fariborz Khorvash (13)
Is There a Relationship Between 24-Hour Urinary Sodium and Potassium and Mental Health in Migraine Patients?: A Cross-Sectional Study
Other Related Docs
4. Effects of the Dietary Approaches to Stop Hypertension (Dash) Diet on Clinical, Quality of Life and Mental Health Outcomes in Women With Migraine: A Randomised Controlled Trial, British Journal of Nutrition (2022)
5. Is There a Link Between the Inflammatory Potential of a Diet and Mental Health Among Patients With Migraine? Findings From a Cross-Sectional Survey, Nutritional Neuroscience (2024)
6. Associations Between Adherence to Mediterranean Dietary Pattern and Frequency, Duration, and Severity of Migraine Headache: A Cross-Sectional Study, Nutritional Neuroscience (2023)
7. Is There an Association Between a Plant-Based Eating Pattern and Clinical Findings of a Migraine Headache?, Frontiers in Nutrition (2023)
8. Associations Between Potential Inflammatory Properties of the Diet and Frequency, Duration, and Severity of Migraine Headaches: A Cross-Sectional Study, Scientific Reports (2022)
9. The Predictive Role of the Dietary Phytochemical Index in Relation to the Clinical and Psychological Traits of Migraine Headaches, Scientific Reports (2024)
10. 24-H Urinary Sodium to Potassium Ratio and Its Association With Obesity in Children and Adolescents, European Journal of Nutrition (2019)
11. Association Between Dietary Acid Load and Clinical Features of Migraine Headaches Among Iranian Individuals, Scientific Reports (2022)
12. Associations Between Dietary Diversity Score and Migraine Headaches: The Results From a Cross-Sectional Study, Frontiers in Nutrition (2023)
13. The Association Between Plant Protein Sources and Migraine Symptoms: A Case-Control Study Among Iranian Adults, Journal of Health System Research (2024)
14. Associations Between Diet Quality and Migraine Headaches: A Cross-Sectional Study, Nutritional Neuroscience (2024)
15. The Association Between Adherence to Alternative Healthy Diet Index (Ahei) and Severity, Disability, Duration, and Frequency of Migraine Headache Among Women: A Cross-Sectional Study, Nutrition Journal (2023)
16. Sodium and Potassium Intakes and Adiposity Among Iranian Pre-Adolescents and Adolescents: A Cross-Sectional Study, Nutrition Journal (2022)
17. The Association Between Diet and Mood: A Systematic Review of Current Literature, Psychiatry Research (2019)
18. Macronutrients and the State of Happiness and Mood in Undergraduate Youth of a Military Training Course, Clinical Nutrition ESPEN (2023)
19. The Effects of the Dietary Approaches to Stop Hypertension (Dash) Diet on Oxidative Stress and Clinical Indices of Migraine Patients: A Randomized Controlled Trial, Nutritional Neuroscience (2022)
20. Low Correlation Between Morning Spot and 24-Hour Urine Samples for Estimating Sodium Intake in an Iranian Population: Isfahan Salt Study, International Journal for Vitamin and Nutrition Research (2019)