Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Can Mesenchymal Stem Cells Derived From Adipose Tissue and Their Conditioned Medium Improve Ovarian Functions? a Mini-Review Publisher Pubmed



Pouryousefikoodehi T1 ; Shayegan S2 ; Hashemi S3 ; Arefnezhad R4 ; Roghanishahraki H5 ; Motedayyen H6 ; Taghizabet N4 ; Rezaeitazangi F7
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Emergency, Milad Hospital, Tehran, Iran
  2. 2. Cyprus University of Health and Social Sciences, Faculty of Pharmacy, Kutlu Adali Boulevard, Guzelyurt, Cyprus
  3. 3. Stem Cell and Regenerative Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Anatomy, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  5. 5. Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Iran
  7. 7. Department of Anatomy, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran

Source: Zygote (Cambridge, England) Published:2022


Abstract

Stable ovarian function is a key factor in the performance of the reproductive system. In contrast, some ovarian function-related diseases, such as polycystic ovarian syndrome, premature ovarian failure (POF), and ovarian cancer, are the main cause of infertility and death of women around the world. Despite multiple attempts, there are no effective tools against these conditions; however, mesenchymal stem cell-based therapy, especially using adipose tissue, has attracted much attention in medicine in light of its advantages such as easy isolation and accessibility. Conversely, it has been suggested that MSC-conditioned medium (CM) can restore injured tissues and has high immunocompatibility. So, here, we will summarize the effects of administration of MSCs and CM derived from adipose tissue on ovarian functions and related diseases.
Related Docs
View other Related Docs
1. Dual Protective and Cytotoxic Benefits of Mesenchymal Stem Cell Therapy in Combination With Chemotherapy/Radiotherapy for Cancer Patients, Critical Reviews in Eukaryotic Gene Expression (2015)
2. Exosomes Derived From Mesenchymal Stem Cells: Heralding a New Treatment for Periodontitis?, Tissue and Cell (2023)
3. Mesenchymal Stem Cell-Derived Extracellular Vesicles: A Novel Cell-Free Therapy, Immunological Investigations (2020)
4. Current Advances in Stem Cell Therapy in the Treatment of Multiple Sclerosis, Reviews in the Neurosciences (2023)
5. Comparative Study of Microtubule-Associated Protein-2 and Glial Fibrillary Acidic Proteins During Neural Induction of Human Bone Marrow Mesenchymal Stem Cells and Adipose-Derived Stem Cells, International Journal of Preventive Medicine (2014)
6. Comparison of Human Mesenchymal Stem Cells Isolated by Explant Culture Method From Entire Umbilical Cord and Wharton’S Jelly Matrix, Cell and Tissue Banking (2014)
7. In Vitro Augmentation of Mesenchymal Stem Cells Viability in Stressful Microenvironments: In Vitro Augmentation of Mesenchymal Stem Cells Viability, Cell Stress and Chaperones (2015)
8. Evaluation of Astaxanthin Effects on the Survival and Proliferation of Human Adipose Derived Stem Cells, Scientific Journal of Kurdistan University of Medical Sciences (2017)
Experts (# of related papers)
View all Related Experts
Nahid Eskandari (3)
Mazdak Ganjalikhani Hakemi (2)
Other Related Docs
9. Therapeutic Effects of Extracellular Vesicles From Human Adipose-Derived Mesenchymal Stem Cells on Chronic Experimental Autoimmune Encephalomyelitis, Journal of Cellular Physiology (2020)