Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Efficacy of Bolus Insulin Calculation by a Mobile-Based Bolus Advisor: An Open Label Clinical Trial Publisher



Siavash M1 ; Taherian M1 ; Khorasgani MA1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Research in Medical Sciences Published:2015


Abstract

Background: We investigated the efficacy of a mobile-based bolus advisor app in comparison with the usual multiple daily injections (MDIs) in diabetic patients. Materials and Methods: In a nonrandomized, controlled clinical trial, 62 diabetic patients were selected to receive a 12-week intensive glycemic control by either a mobile-based bolus advisor (app) or MDI in the usual manner. We compared mean blood glucose (BG) and HbA1c before and just after the treatment program. The data were analyzed using paired sample t-test and analysis of variance (ANOVA). Results: Fifty-six patients (30 cases and 26 controls) completed the study. The mean [standard deviation (SD)] of BG was 220.57 (43.7) and 231.5 (55) in the app group and control group, respectively. Mean BG decreased 38 mg/dL in the app and 16 mg/dL in the control group (P = 0.001 and 0.049 respectively). Changes of mean BG were different between the two groups significantly (P = 0.039). HbA1c decreased from 8.4% to 7.6% in the case and from 8.4% to 8% in the control group (P = 0.001 and 0.06, respectively). Changes of HbA1c were not different between the two groups (P = 0.141). The mean episodes of hypoglycemia were not different between the groups significantly (P = 0.108). Conclusion: In conclusion, this study revealed that mobile-based bolus advisors can reduce mean BG better in patients who are planned to have a tight glycemic control as a feasible and available method and may improve HbA1c in the long term. © 2015 Journal of Research in Medical Sciences.
Related Docs
View other Related Docs
1. Dapagliflozin: An Effective Adjunctive Treatment in Type 1 Diabetes, Cardiovascular Endocrinology and Metabolism (2021)
2. Benefits of Metformin Combined With Insulin in Children With Type 1 Diabetes Mellitus, Shiraz E Medical Journal (2011)
3. Effects of Dietary Approaches to Stop Hypertension Diet Versus Usual Dietary Advice on Glycemic Indices in Women at Risk for Cardiovascular Disease; a Randomized Controlled Clinical Trial, Journal of Renal Injury Prevention (2017)
4. Short- and Long-Term Effects of Capsaicin Supplementation on Glycemic Control: A Systematic Review and Meta-Analysis of Controlled Trials, Food and Function (2021)
5. Influence of Walking Training on Haemoglobin Glucosile and Fasting Blood Sugar Levels in Women With Type 2 Diabetes, Koomesh (2010)
6. The Product of Triglycerides and Glucose in Comparison With Fasting Plasma Glucose Did Not Improve Diabetes Prediction, Acta Diabetologica (2015)
7. The Effects of Berberis Integerrima Fruit Extract on Glycemic Control Parameters in Patients With Type 2 Diabetes Mellitus: A Randomized Controlled Clinical Trial, Evidence-based Complementary and Alternative Medicine (2021)
8. L-Carnitine Supplementation Ameliorates Insulin Resistance in Critically Ill Acute Stroke Patients: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial, Research in Pharmaceutical Sciences (2022)
Experts (# of related papers)
View all Related Experts
Shadi Farsaei (5)
Bijan Iraj (5)
Other Related Docs
9. Efficacy and Safety of Oral Insulin Compared to Subcutaneous Insulin: A Systematic Review and Meta-Analysis, Journal of Endocrinological Investigation (2016)
10. The Effectiveness of Cognitive-Behavioral Stress Mmanagement Training on Glycemic Control and Depression in Patients With Type 2 Diabetes, Iranian Journal of Endocrinology and Metabolism (2009)
11. The Freestyle Libre Flash Glucose Monitoring System: How It Has Improved Glycaemic Control for People With Type 1 Diabetes in Eastern Cheshire, Uk, Cardiovascular Endocrinology and Metabolism (2020)
12. Effect of Fenugreek Seeds on Blood Glucose and Lipid Profiles in Type 2 Diabetic Patients, International Journal for Vitamin and Nutrition Research (2009)
13. Progression to Impaired Glucose Metabolism in First-Degree Relatives of Patients With Type 2 Diabetes in Isfahan, Iran, Diabetes/Metabolism Research and Reviews (2009)
14. Secondary Prevention by Enhancing Adherence in Diabetic Patients, International Journal of Preventive Medicine (2010)
15. A Comparative Study of the Effect of Two Procedures of Classic Roux-En-Y and Omega Bariatric Surgery on the Control and Management of Diabetes, Advanced Biomedical Research (2022)
16. Therapeutic Effect of Fenugreek Supplementation on Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Clinical Trials, Heliyon (2024)
17. Clinical Trial of the Effects of Coenzyme Q10 Supplementation on Glycemic Control and Markers of Lipid Profiles in Diabetic Hemodialysis Patients, International Urology and Nephrology (2018)
18. Incidence of Type 2 Diabetes by Hba1c and Ogtt: The Isfahan Diabetes Prevention Study, Acta Diabetologica (2012)
19. Impact of Pharmaceutical Care on Quality of Life in Patients With Type 2 Diabetes Mellitus, Journal of Research in Medical Sciences (2011)
20. The Effect of Home Visit Program on Self-Management Behaviors and Glycemic Control in Patients With Type 2 Diabetes Treated With Insulin, Journal of Isfahan Medical School (2020)
21. Weight Change, Blood Pressure, Lipids and Glycemic Control Among Patients With Type 2 Diabetes, Annals of Nutrition and Metabolism (2011)
22. Developing “Aryan:” Diabetes Self‑Care Mobile Application, International Journal of Preventive Medicine (2019)
23. Effect of Pharmacist-Led Patient Education on Glycemic Control of Type 2 Diabetics: A Randomized Controlled Trial, Journal of Research in Medical Sciences (2010)
24. Dexamethasone Stress Test: A Pilot Clinical Study for Identification of Individuals Highly Prone to Develop Type 2 Diabetes, Endocrine Practice (2018)
25. Effects of Paleolithic Diet on Glucose Control in Adults: A Systematic Review and Meta-Analysis of Controlled Clinical Trials, Journal of Nutrition and Food Security (2019)
26. Group Education and Nurse-Telephone Follow-Up Effects on Blood Glucose Control and Adherence to Treatment in Type 2 Diabetes Patients, International Journal of Preventive Medicine (2013)
27. The Effects of Magnesium Supplementation on Blood Pressure and Obesity Measure Among Type 2 Diabetes Patient: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Biological Trace Element Research (2021)
28. Effect of Sodium–Glucose Cotransporter 2 Inhibitors on Insulin Resistance; a Systematic Review and Meta-Analysis, Acta Diabetologica (2023)
29. The Effect of Hydroalcoholic Saffron (Crocus Sativus L.) Extract on Fasting Plasma Glucose, Hba1c, Lipid Profile, Liver, and Renal Function Tests in Patients With Type 2 Diabetes Mellitus: A Randomized Double-Blind Clinical Trial, Phytotherapy Research (2019)
30. Effect of Pharmacist-Led Patient Education on Glycemic Control of Type 2 Diabetics: A Randomized Controlled Trial, Journal of Research in Medical Sciences (2011)
31. Effects of Cynara Scolymus L. on Glycemic Indices:A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Complementary Therapies in Medicine (2020)
32. Evaluation of the Accuracy of the Glycated Hemoglobin (Hba1c) Index Measured by the Clover A1c Self Analyzer Device Compared to Standard Methods; [(Clover A1c Self Analyz) توسط دستگاه (Hba1c) بررسی صحت انداز هگیری هموگلوبی ن گلیکوز یله در مقایسه با رو شهای استاندارد School], Journal of Isfahan Medical School (2025)
33. Glycemic Control Among Iranian People With Type 2 Diabetes: A Systematic Review and Meta-Analysis, International Journal of Diabetes in Developing Countries (2023)
34. The Effects of Berberis Vulgaris Juice on Insulin Indices in Women With Benign Breast Disease: A Randomized Controlled Clinical Trial, Iranian Journal of Pharmaceutical Research (2018)
35. The Relationship of Laboratory Results and Cognitive Function in Patient With Type I and Type Ii Diabetes Mellitus, Journal of Isfahan Medical School (2013)
36. Salsalate Improves Glycemic Control in Patients With Newly Diagnosed Type 2 Diabetes, Acta Diabetologica (2013)
37. Effect of Dexamethasone on Glucose Homeostasis in Normal and Prediabetic Subjects With a First-Degree Relative With Type 2 Diabetes Mellitus, Endocrine Practice (2012)
38. Development and Primary Evaluation of a Smartphone Application for Blood Glucose Control in Hospitalized Patients, Advanced Biomedical Research (2019)
39. Current Status of Glucose, Blood Pressure and Lipid Management in Type 2 Diabetes Clinic Attendees in Isfahan, Iran, Journal of Diabetes Investigation (2015)
40. Effect of Telephone Follow-Up by Nurses on Self-Care in Children With Diabetes, Iranian Journal of Nursing and Midwifery Research (2018)
41. Adherence to Glyburide and Metformin and Associated Factors in Type 2 Diabetes in Isfahan, Iran, Iranian Journal of Pharmaceutical Research (2011)
42. The Effects of Oral Magnesium Supplementation on Glycaemic Control in Patients With Type 2 Diabetes: A Systematic Review and Dose-Response Meta-Analysis of Controlled Clinical Trials, British Journal of Nutrition (2022)
43. Cardiovascular Risk Factors in Relatives of Type 2 Diabetics With Normal Glucose Tolerance Test and Elevated One-Hour Plasma Glucose, Endokrynologia Polska (2010)
44. Application of Basnef Educational Model for Nutritional Education Among Elderly Patients With Type 2 Diabetes: Improving the Glycemic Control, Journal of Research in Medical Sciences (2011)
45. Diabetes and Impaired Glucose Regulation in First-Degree Relatives of Patients With Type 2 Diabetes in Isfahan, Iran: Prevalence and Risk Factors, Review of Diabetic Studies (2007)
46. The Effect of Nutrition Education on Risk Factors of Cardiovascular Diseases in Elderly Patients With Type 2 Diabetes: A Randomized Controlled Trial, Iranian Journal of Endocrinology and Metabolism (2011)
47. Should the First Degree Relatives of Type 2 Diabetic Patients With Isolated Impaired Fasting Glucose Be Considered for a Diabetes Primary Prevention Program?, Journal of Research in Medical Sciences (2010)
48. The Perceived Self-Efficacy and Its Interrelation With Communication in Family and Glycemic Control in Adolescents With Type 1 Diabetes, Pakistan Journal of Medical Sciences (2013)
49. Glycemic Control in the Infectious Diseases Ward; Role of Clinical Pharmacist Interventions, Journal of Infection in Developing Countries (2014)
50. Effects of Chromium Supplementation on Glycemic Control in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Pharmacological Research (2020)