Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells Publisher

Dheyab MA^{1, 2} ; Aziz AA^{1, 2} ; Jameel MS^{1, 2} ; Khaniabadi PM^{1, 2} ; Mehrdel B^{1, 2} ; Khaniabadi BM³

Source: Journal of Physics: Conference Series Published:2020

Abstract

Iron oxide nanoparticles (Fe3O4 NPs) possess unique physicochemical properties which make them great for biomedical applications. This study reports the development of gold (Au) coated Fe3O4 (Au-Fe3O4 NPs) for photothermal therapy to eradicate breast cancer cells (MCF-7). The spherical shape of monodisperse Au-Fe3O4 NPs with an average size of 20.8 nm was confirmed by TEM. The cell viability evaluation of Au-Fe3O4 NPs showed negligible toxicity toward MCF-7 cells after 24 h. Significant cell reduction was observed for MCF-7 (73.9%) cells following photothermal therapy at highest concentration of NPs (50 μgFe/ml) for 10 minutes illumination when compared with other intervention groups. It can be concluded that, the synthesized Au-Fe3O4 NPs is an effective and promising photothermal therapy agent for breast cancer treatment. © 2020 IOP Publishing Ltd. All rights reserved.

Related Docs

View other Related Docs

1. Targeted Photothermal Therapy of Melanoma in C57bl/6 Mice Using Fe3 O4 @Au Core-Shell Nanoparticles and Near-Infrared Laser, Journal of Biomedical Physics and Engineering (2021)

2. Optimal Scheduling of the Nanoparticle-Mediated Cancer Photo-Thermo-Radiotherapy, Photodiagnosis and Photodynamic Therapy (2020)

3. Iron Oxide Nanoparticles Coated With Polydopamine As a Potential Nano-Photothermal Agent for Treatment of Melanoma Cancer: An in Vivo Study, Lasers in Medical Science (2022)

Experts (# of related papers)

View all Related Experts

Daryoush Shahbazi-Gahrouei (13)

Mahboubeh Rostami (2)

Other Related Docs

4. Assessment of Ploy Dopamine Coated Fe3o4 Nanoparticles for Melanoma (B16-F10 and A-375) Cells Detection, Anti-Cancer Agents in Medicinal Chemistry (2020)

5. Synthesis and Application of Fe3o4@Au Composite Nanoparticles As Magnetic Resonance/Computed Tomography Dual-Modality Contrast Agent, Journal of Medical Signals and Sensors (2020)

6. Trastuzumab Conjugated Porphyrin-Superparamagnetic Iron Oxide Nanoparticle: A Potential Ptt-Mri Bimodal Agent for Herceptin Positive Breast Cancer, Photodiagnosis and Photodynamic Therapy (2020)

7. Breast Cancer Cell Targeted Mr Molecular Imaging Probe: Anti-Muc1 Antibody-Based Magnetic Nanoparticles, Journal of Physics: Conference Series (2017)

8. Investigation of Combination Effect Between 6 Mv X-Ray Radiation and Polyglycerol Coated Superparamagnetic Iron Oxide Nanoparticles on U87-Mg Cancer Cells, Journal of Biomedical Physics and Engineering (2020)

9. Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent, International Journal of Polymeric Materials and Polymeric Biomaterials (2021)

10. Detection of Muc1-Expressing Ovarian Cancer by C595 Monoclonal Antibody-Conjugated Spions Using Mr Imaging, The Scientific World Journal (2013)

11. In-Vitro Toxicity Assessment of Polydopamine-Coated and Uncoated Fe3o4 Nanoparticles in Cell Line B16-F10 (Melanoma Cell), Journal of Isfahan Medical School (2019)

12. In Vitro Investigation of Radiotherapy Along With Gemcitabine Loaded Peg Gold Nanoparticles Against Mcf-7 Breast Cancer Cells, Advanced Biomedical Research (2025)

13. Assessment of Manganese-Zinc Ferrite Nanoparticles As a Novel Magnetic Resonance Imaging Contrast Agent for the Detection of 4T1 Breast Cancer Cells, Journal of Medical Signals and Sensors (2019)

14. Architecting Ultra-Thin Sio2 Shell for High Magnetic Performance of Fe3o4 Nanoparticles for Biomedical Applications, Inorganic Chemistry Communications (2024)

15. Fabrication and Characterization Smart Gold-Polymer Nanostructure As Promising Theranostic Agent for Dual-Imaging and Chemo-Photothermal Therapy of Cancer: An in Vitro Study, Journal of Photochemistry and Photobiology A: Chemistry (2024)

16. In Vitro Study of Spions-C595 As Molecular Imaging Probe for Specific Breast Cancer (Mcf-7) Cells Detection, Iranian Biomedical Journal (2017)

17. Study the Anti-Muc1 Antibody-Based Iron Oxide Nanoparticles on Three-Dimension Spheroid and Breast Cancer (Mcf-7) Cell Imaging, Polish Journal of Medical Physics and Engineering (2019)

18. Thermosensitive Tmpo-Oxidized Lignocellulose/Cationic Agarose Hydrogel Loaded With Deferasirox Nanoparticles for Photothermal Therapy in Melanoma, International Journal of Biological Macromolecules (2023)

19. Preparation and Magnetic Properties Investigation of Fe3o4 Nanoparticles Labaled With 99Mtc Radioisotope and Fe3o4 Nanoparticles Dmsa Coated, Digest Journal of Nanomaterials and Biostructures (2011)

20. Multifunctional Magnetic Nanostructured Hardystonite Scaffold for Hyperthermia, Drug Delivery and Tissue Engineering Applications, Materials Science and Engineering C (2017)

Style	Citing Format
MLA	Dheyab MA, et al.. "Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells." Journal of Physics: Conference Series, vol. 1497, no. 1, 2020, pp. -.
APA	Dheyab MA, Aziz AA, Jameel MS, Khaniabadi PM, Mehrdel B, Khaniabadi BM (2020). Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells. Journal of Physics: Conference Series, 1497(1), -.
Chicago	Dheyab MA, Aziz AA, Jameel MS, Khaniabadi PM, Mehrdel B, Khaniabadi BM. "Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells." Journal of Physics: Conference Series 1497, no. 1 (2020): -.
Harvard	Dheyab MA et al. (2020) 'Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells', Journal of Physics: Conference Series, 1497(1), pp. -.
Vancouver	Dheyab MA, Aziz AA, Jameel MS, Khaniabadi PM, Mehrdel B, Khaniabadi BM. Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells. Journal of Physics: Conference Series. 2020;1497(1):-.
BibTex	@article{ author = {Dheyab MA and Aziz AA and Jameel MS and Khaniabadi PM and Mehrdel B and Khaniabadi BM}, title = {Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells}, journal = {Journal of Physics: Conference Series}, volume = {1497}, number = {1}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Dheyab MA AU - Aziz AA AU - Jameel MS AU - Khaniabadi PM AU - Mehrdel B AU - Khaniabadi BM TI - Gold-Coated Iron Oxide Nanoparticles As a Potential Photothermal Therapy Agent to Enhance Eradication of Breast Cancer Cells JO - Journal of Physics: Conference Series VL - 1497 IS - 1 SP - EP - PY - 2020 ER -

Science Communicator Platform

Authors

Abstract