Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Anti-Oxidative and Anti-Inflammatory Effects of Ginger in Health and Physical Activity: Review of Current Evidence



Mashhadi NS1 ; Ghiasvand R2, 3 ; Askari G2, 3 ; Hariri M2, 3 ; Darvishi L2, 3 ; Mofid MR4
Authors
Show Affiliations
Authors Affiliations
  1. 1. Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Biochemistry, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran

Source: International Journal of Preventive Medicine Published:2013

Abstract

Background: Ginger (Zingiber officinale Rosc.) belongs to the family Zingiberaceae. The health-promoting perspective of ginger is attributed to its rich phytochemistry. This study aimed to review the current evidence on ginger effects as an anti-inflammatory and anti-oxidative. Methods: We searched MEDLINE for related publications using “ginger” and “anti-oxidative” and “ginger” and “anti-inflammatory” as keywords. This search had considered Papers that had been published between 2000 and 2010 without any filter. Conclusions: The anticancer potential of ginger is well documented and its functional ingredients like gingerols, shogaol, and paradols are the valuable ingredients which can prevent various cancers. This review concludes to favor ginger but some ambiguities necessitate further research before claiming its efficacy. © 2013, Isfahan University of Medical Sciences(IUMS). All rights reserved.
Related Docs
View other Related Docs
1. Effect of Ginger Supplementation on Liver Enzymes: A Systematic Review and Meta-Analysis, Current Nutrition and Food Science (2024)
2. Ginger As an Anticolorectal Cancer Spice: A Systematic Review of in Vitro to Clinical Evidence, Food Science and Nutrition (2023)
3. The Effects of Ginger Supplementation on Markers of Inflammatory and Oxidative Stress: A Systematic Review and Meta-Analysis of Clinical Trials, Phytotherapy Research (2020)
4. The Effects of Ginger Supplementation on Biomarkers of Inflammation and Oxidative Stress in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Journal of Herbal Medicine (2020)
5. The Effect of Ginger Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Clinical Trials, Phytomedicine (2018)
6. Effect of Ginger (Zingiber Officinale) on Blood Glucose and Lipid Concentrations in Diabetic and Hyperlipidemic Subjects: A Meta-Analysis of Randomized Controlled Trials, Journal of Functional Foods (2017)
7. Effect of Ginger (Zingiber Officinale) on Inflammatory Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Cytokine (2020)
8. Does Ginger Supplementation Lower Blood Pressure? a Systematic Review and Meta-Analysis of Clinical Trials, Phytotherapy Research (2019)
Experts (# of related papers)
View all Related Experts
Mohammad Bagherniya (5)
Gholamreza Askari (4)
Other Related Docs
9. Comparison of Anti-Inflammatory and Analgesic Effects of Ginger Powder and Ibuprofen in Postsurgical Pain Model: A Randomized, Double-Blind, Case-Control Clinical Trial, Dental Research Journal (2017)
10. Anti-Ulcerogenic Effect of Ginger (Rhizome of Zingiber Officinale Roscoe) on Cystemine Induced Duodenal Ulcer in Rats, Daru (2006)
11. Comparison of Effects of Ginger, Mefenamic Acid, and Ibuprofen on Pain in Women With Primary Dysmenorrhea, Journal of Alternative and Complementary Medicine (2009)
12. Regulation of Apolipoprotein B by Natural Products and Nutraceuti-Cals: A Comprehensive Review, Current Medicinal Chemistry (2021)
13. Different Delivery Systems for Improving the Bioavailability of Ginger Bioactive Compounds: A Comprehensive Review, Phytochemistry Reviews (2025)
14. The Effects of 6-Gingerol on Reproductive Improvement, Liver Functioning and Cyclooxygenase-2 Gene Expression in Estradiol Valerate – Induced Polycystic Ovary Syndrome in Wistar Rats, Biochemical and Biophysical Research Communications (2017)
15. The Effect of Frankincense (Boswellia Serrata, Oleoresin) and Ginger (Zingiber Officinale, Rhizoma) on Heavy Menstrual Bleeding: A Randomized, Placebo-Controlled, Clinical Trial, Complementary Therapies in Medicine (2019)
16. Medicinal Plants and Phytochemicals Regulating Insulin Resistance and Glucose Homeostasis in Type 2 Diabetic Patients: A Clinical Review, Advances in Experimental Medicine and Biology (2021)
17. Preventive and Curative Effects of Ginger Extract Against Histopathologic Changes of Gentamicin-Induced Tubular Toxicity in Rats, International Journal of Preventive Medicine (2013)
18. The Effects of Phytochemicals and Herbal Bio-Active Compounds on Tumour Necrosis Factor-Α in Overweight and Obese Individuals: A Clinical Review, Inflammopharmacology (2022)
19. The Effects of Medicinal Plants and Bioactive Natural Compounds on Homocysteine, Molecules (2021)
20. Herbal Remedies As Potential in Cartilage Tissue Engineering: An Overview of New Therapeutic Approaches and Strategies, Molecules (2020)
21. Protective Potential of Naringenin and Its Nanoformulations in Redox Mechanisms of Injury and Disease, Heliyon (2023)
22. Application of Some Herbal Medicine Used for the Treatment of Osteoarthritis and Chondrogenesis, Traditional and Integrative Medicine (2020)
23. The Effects of Herbal Medicines on Cancer Therapy-Induced Oral Mucositis: A Literature Review, Phytotherapy Research (2022)
24. Rosemary and Its Protective Potencies Against Covid-19 and Other Cytokine Storm Associated Infections: A Molecular Review, Mediterranean Journal of Nutrition and Metabolism (2021)
25. Effects of Curcuma, Black Pepper, and Ginger on the Pain and Performance of Patients With Chronic Knee Osteoarthritis, Journal of Health System Research (2020)
26. The Efficacy and Safety of Ginger Supplementation in Patients With Multiple Sclerosis: A Rationale and Study Protocol for a Double-Blind Randomized Controlled Trial, Health Science Reports (2023)
27. In Vitro and in Vivo Production of Gingerols and Zingiberene in Ginger Plant (Zingiber Officinale Roscoe), Iranian Journal of Pharmaceutical Sciences (2011)
28. The Effect of Zingiber Officinale Extract on Preventing Demyelination of Corpus Callosum in a Rat Model of Multiple Sclerosis, Iranian Biomedical Journal (2022)
29. The Preventive Effect of Zingiber Officinale Essential Oil on Demyelination of Corpus Callosum in a Cuprizone Rat Model of Multiple Sclerosis, Avicenna Journal of Phytomedicine (2023)
30. Herbal Formulation “Turmeric Extract, Black Pepper, and Ginger” Versus Naproxen for Chronic Knee Osteoarthritis: A Randomized, Double-Blind, Controlled Clinical Trial, Phytotherapy Research (2020)
31. Effects of Cinnamon, Cardamom, Saffron, and Ginger Consumption on Markers of Glycemic Control, Lipid Profile, Oxidative Stress, and Inflammation in Type 2 Diabetes Patients, The review of diabetic studies : RDS (2014)
32. The Effect of Ginger and Cinnamon Consumption on Chemotherapy-Induced Nausea and Vomiting: A Double-Blind Randomized Clinical Trial; [تأثیر مصرف زنجبیل و دارچین بر تهوع و استفراغ ناشی از شیمی درمانی-کارآزمایی بالینی تصادفی دو سوکور], Journal of Isfahan Medical School (2022)
33. The Protective Effects of Ginger on the Development of Coronary Atherosclerosis: An Experimental Animal Study, Der Pharmacia Lettre (2016)
34. Effect of Ginger (Zingiber Officinale) Intake on Human Serum Lipid Profile: Systematic Review and Meta-Analysis, Phytotherapy Research (2023)
35. The Effects of Ginger Supplementation on Common Gastrointestinal Symptoms in Patients With Relapsing-Remitting Multiple Sclerosis: A Double-Blind Randomized Placebo-Controlled Trial, BMC Complementary Medicine and Therapies (2023)
36. Ameliorative Effects of Ginger on Allergic Diseases: An Updated Review, Molecular Nutrition and Food Research (2024)