The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina

The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina Publisher

Sadeghi M¹ ; Moslehi M² ; Teimourijervekani Z¹ ; Shahraki H¹

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1. Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2. Department of Nuclear Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2020

Abstract

Background: In a person with significant coronary artery disease (CAD), exercise stress can cause reversible myocardial ischemia, which is detectable by single photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI). The aim of present study was to investigate the relationship between post-exercise high-sensitive cardiac troponin I (hs-cTnI) serum levels and result of SPECT-MPI as a gold standard. Methods: In this cross-sectional study, 82 patients with no previous history of CAD or any organic disease were evaluated. hs-cTnI serum levels were monitored 75 minutes after the peaked of exercise (achievement to at least 85% of maximum heart rate), and compared with reversible myocardial ischemia. After 3 months, patients' prognosis and continued chest pain were evaluated. Findings: The mean age of the patients was 59.4 ± 11.1, and 60 patients (73%) were women. In 29 patients, reversible myocardial ischemia was detected. There was a significant correlation between hs-cTnI serum level and reversible myocardial ischemia (P = 0.005); but no significant relationship was seen with infarcted myocardial tissue (P = 0.063). Based on SPECT-MPI, the hs-cTnI serum amount of 1.6 ng/dl, as likely as hs-cTnI cut-off level, represented the specificity of 70%, sensitivity of 69%, positive predictive value of 55%, and negative predictive value of 80%. There was no significant relationship between hs-cTnI level and prognosis or chest pain after 3 months. Conclusion: The serum level of hs-cTnI after exercise was higher in the group with reversible myocardial ischemia. © 2016 Isfahan University of Medical Sciences(IUMS). All rights reserved.

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Masoumeh Sadeghi (4)

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Style	Citing Format
MLA	Sadeghi M, et al.. "The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina." Journal of Isfahan Medical School, vol. 38, no. 568, 2020, pp. 172-179.
APA	Sadeghi M, Moslehi M, Teimourijervekani Z, Shahraki H (2020). The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina. Journal of Isfahan Medical School, 38(568), 172-179.
Chicago	Sadeghi M, Moslehi M, Teimourijervekani Z, Shahraki H. "The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina." Journal of Isfahan Medical School 38, no. 568 (2020): 172-179.
Harvard	Sadeghi M et al. (2020) 'The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina', Journal of Isfahan Medical School, 38(568), pp. 172-179.
Vancouver	Sadeghi M, Moslehi M, Teimourijervekani Z, Shahraki H. The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina. Journal of Isfahan Medical School. 2020;38(568):172-179.
BibTex	@article{ author = {Sadeghi M and Moslehi M and Teimourijervekani Z and Shahraki H}, title = {The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina}, journal = {Journal of Isfahan Medical School}, volume = {38}, number = {568}, pages = {172-179}, year = {2020} }
RIS	TY - JOUR AU - Sadeghi M AU - Moslehi M AU - Teimourijervekani Z AU - Shahraki H TI - The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient With Cardiac Angina JO - Journal of Isfahan Medical School VL - 38 IS - 568 SP - 172 EP - 179 PY - 2020 ER -

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