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Comparison of Indocyanine Green Angiography and Fluorescein Angiography for Imaging of Central Serous Chorioretinopathy Patients As Candidates for Photodynamic Therapy; [Comparaison De L'angiographie Au Vert D'indocyanine Et De L'angiographie a La Fluoresceine Pour L'imagerie Des Patients Atteints De Chorioretinopathie Sereuse Centrale Candidats a La Therapie Photodynamique] Publisher Pubmed



Kianersi F1 ; Masjedi M1 ; Razmjoo H1 ; Ghanbari H1 ; Fazel F1 ; Dehghani A1 ; Akhlaghi M1 ; Salehi A1 ; Baghi A2 ; Pourazizi M1
Authors
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Authors Affiliations
  1. 1. Department of Ophthalmology, Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Didavaran Eye Clinic, Isfahan, Iran

Source: Journal Francais d'Ophtalmologie Published:2022


Abstract

Purpose: To compare fluorescein angiography (FA) and indocyanine green angiography (ICGA) for imaging of central serous chorioretinopathy (CSC) patients. Methods: The observational cross-sectional clinical study was conducted on 131 eyes of 131 patients with CSC who were candidates for photodynamic therapy (PDT). An experienced ophthalmologist marked the leakage sites and choroidal hyperpermeability sites that needed PDT. For each eye, simultaneous FA and ICGA imaging with the maximum leakage area was selected for comparison regarding the site and size. Results: The mean ± standard deviation age of patients was 44.53 ± 9.03 years. Of 226 leakage points, 177 (78.32%) points were in the same site, and 168 (74.34%) points were in the same size on FA. No statistical difference was found between age (P = 0.45), sex (P = 0.32), and chronicity (P = 0.11) of the disease in comparing the ICGA images to the FA images regarding leakage at the same site. A statistically significant difference was also found regarding size of leakage and chronicity (P < 0.001). Conclusion: The current results suggested that FA could be considered an alternative ocular imaging technology as a guide for PDT in CSC patients. © 2021
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