Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection

Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection Publisher

Malekzad H¹ ; Sahandi Zangabad P^{2, 3, 4, 5, 6, 7} ; Mohammadi H⁸ ; Sadroddini M⁹ ; Jafari Z¹⁰ ; Mahlooji N¹¹ ; Abbaspour S¹² ; Gholami S¹³ ; Ghanbarpoor M¹³ ; Pashazadeh R¹ ; Beyzavi A¹⁴ ; Karimi M^{3, 7, 15, 16, 17} ; Hamblin MR^{17, 18, 19}

Show Affiliations

1. Advanced Nanobiotechnology and Nanomedicine Research Group (ANNRG), Iran
2. Research Center for Pharmaceutical Nanotechnology (RCPN), Tabriz University of Medical Science (TUOMS), Tabriz, Iran
3. Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia
4. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran
5. Bio-Nano-Interfaces: Convergence of Sciences (BNICS), Universal Scientific Education and Research Network (USERN), Tehran, Iran
6. Nanomedicine Research Association (NRA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
7. Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
8. Young Researchers and Elite Club, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran
9. Polymer Engineering Department, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran
10. Department of Food Science and Technology, College of Agriculture and Food Science, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
11. Department of Chemistry, Semnan University, Semnan, 35351-19111, Iran
12. School of Science and Engineering, Sharif University of Technology, International Campus, Iran
13. Tarbiat Modares University, Tehran, Iran
14. Koch Institute of MIT, 500 Main Street, Cambridge, MA, United States
15. Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran
16. Applied Biotechnology Research Center, Teheran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
17. Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, 02114, MA, United States
18. Department of Dermatology, Harvard Medical School, Boston, 02115, MA, United States
19. Harvard-MIT Division of Health Sciences and Technology, Cambridge, 02139, MA, United States

Source: TrAC - Trends in Analytical Chemistry Published:2018

Abstract

Nanotechnology has illustrated significant potentials in biomolecular-sensing applications; particularly its introduction to anti-doping detection is of great importance. Illicit recreational drugs, substances that can be potentially abused, and drugs with dosage limitations according to the prohibited lists announced by the World Antidoping Agency (WADA) are becoming of increasing interest to forensic chemists. In this review, the theoretical principles of optical biosensors based on noble metal nanoparticles, and the transduction mechanism of commonly-applied plasmonic biosensors are covered. We review different classes of recently-developed plasmonic biosensors for analytic determination and quantification of illicit drugs in anti-doping applications. The important classes of illicit drugs include anabolic steroids, opioids, stimulants, and peptide hormones. The main emphasis is on the advantages that noble metal nanoparticles bring to optical biosensors for signal enhancement and the development of highly sensitive (label-free) biosensors. In the near future, such optical biosensors may be an invaluable substitute for conventional anti-doping detection methods such as chromatography-based approaches, and may even be commercialized for routine anti-doping tests. © 2017 Elsevier B.V.

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Style	Citing Format
MLA	Malekzad H, et al.. "Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection." TrAC - Trends in Analytical Chemistry, vol. 100, no. , 2018, pp. 116-135.
APA	Malekzad H, Sahandi Zangabad P, Mohammadi H, Sadroddini M, Jafari Z, Mahlooji N, Abbaspour S, Gholami S, Ghanbarpoor M, Pashazadeh R, Beyzavi A, Karimi M, Hamblin MR (2018). Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection. TrAC - Trends in Analytical Chemistry, 100(), 116-135.
Chicago	Malekzad H, Sahandi Zangabad P, Mohammadi H, Sadroddini M, Jafari Z, Mahlooji N, Abbaspour S, et al.. "Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection." TrAC - Trends in Analytical Chemistry 100, no. (2018): 116-135.
Harvard	Malekzad H et al. (2018) 'Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection', TrAC - Trends in Analytical Chemistry, 100(), pp. 116-135.
Vancouver	Malekzad H, Sahandi Zangabad P, Mohammadi H, Sadroddini M, Jafari Z, Mahlooji N, et al.. Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection. TrAC - Trends in Analytical Chemistry. 2018;100():116-135.
BibTex	@article{ author = {Malekzad H and Sahandi Zangabad P and Mohammadi H and Sadroddini M and Jafari Z and Mahlooji N and Abbaspour S and Gholami S and Ghanbarpoor M and Pashazadeh R and Beyzavi A and Karimi M and Hamblin MR}, title = {Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection}, journal = {TrAC - Trends in Analytical Chemistry}, volume = {100}, number = {}, pages = {116-135}, year = {2018} }
RIS	TY - JOUR AU - Malekzad H AU - Sahandi Zangabad P AU - Mohammadi H AU - Sadroddini M AU - Jafari Z AU - Mahlooji N AU - Abbaspour S AU - Gholami S AU - Ghanbarpoor M AU - Pashazadeh R AU - Beyzavi A AU - Karimi M AU - Hamblin MR TI - Noble Metal Nanostructures in Optical Biosensors: Basics, and Their Introduction to Anti-Doping Detection JO - TrAC - Trends in Analytical Chemistry VL - 100 IS - SP - 116 EP - 135 PY - 2018 ER -

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