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Biomarker Sensing Using Luminescent Metal Nanoclusters Publisher



Tarokh A1 ; Hosseini M1, 2
Authors
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Authors Affiliations
  1. 1. Nanobiosensors Lab, Department of Life Science Engineering, University of Tehran, Tehran, Iran
  2. 2. Medical Biomaterials Research Center, University of Medical Sciences, Tehran, Iran

Source: Luminescent Metal Nanoclusters: Synthesis# Characterization# and Applications Published:2022


Abstract

Metal nanoclusters (MNCs) as a special group of nanoparticles consisting of only a few atoms illustrate unique features for biomarker sensing. The outstanding optical, electrical, and reactivity properties of nanoclusters, besides their ultra-small size (typically less than 2nm), photostability, low toxicity, biocompatibility, and low photobleaching made them an eligible option for biological sensing applications. Some special properties of different MNCs (AgNC, AuNC, CuNP, PtNC, etc.) such as high photoluminescence, intense electrochemiluminescence, and unique physiochemical properties have opened up several new prospects for detecting important disease-related biomarkers. This chapter aims to provide insights into the development of nanocluster-based biosensing systems for the detection of some worthwhile biomarkers, which can lead to early diagnosis of different devastating diseases such as cancer and cardiovascular disease. © 2022 Elsevier Ltd. All rights reserved.
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