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Mechanisms and Potentials of Stem Cells in the Treatment of Multiple Sclerosis: The Unpaved Path Publisher



Bonab MM1 ; Shakiba Y1 ; Talebian F2 ; Nikbin B1
Authors
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Authors Affiliations
  1. 1. Department of Immunology, College of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pathology, The Ohio State University, Columbus, OH, United States

Source: Multiple Sclerosis: A Mechanistic View Published:2016


Abstract

Multiple sclerosis (MS) is predominantly considered an immune-mediated chronic disease, with complicated pathogenesis and clinical signs of paralysis. MS is an inflammatory disease of the central nervous system in which T lymphocytes show a second phase of activation. This activation is followed by axonal demyelination and neurological disorder manifestations. In most patients, the disease is associated with axonal loss and progressive disabilities. © 2016 Elsevier Inc. All rights reserved.
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