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Non-Albicans Candida Necrotizing Fasciitis After Gynecology Oncology Surgery Publisher



Yousefi M1 ; Yarandi F2 ; Shirali E2 ; Rajabzadeh S3 ; Nazemi P3
Authors
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Authors Affiliations
  1. 1. Department of Gynecology, School of Medicine, Qom University of Medical Sciences, Tehran, Iran
  2. 2. Department of Gynecology-Oncology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Infectious Diseases, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Obstetrics, Gynecology and Cancer Research Published:2025


Abstract

Necrotizing fasciitis, a rare and potentially lethal infection, is characterized by rapid and progressive involvement of the fascia and subcutaneous tissues. Here, we reported a 55-year-old woman with a history of recent surgery with complaints of erythema and foul-smelling discharge from the surgical incision site. The surgical incision site was opened, and cleaned with a sizable sterile normal saline, and the patient underwent ceftazidime, levofloxacin, metronidazole, and vancomycin. According to the results of microbiological cultures, non-albicans candida and its resistance to fluconazole, caspofungin, were substituted. However, necrotizing fasciitis increased. The rapid recognition, aggressive surgical intervention, and targeted antimicrobial therapy collectively played a pivotal role in successful recovery. The rapid recognition, aggressive surgical intervention, and targeted antimicrobial therapy collectively played a pivotal role in successful recovery. This case underscores the importance of vigilance in monitoring postoperative patients, particularly those with risk factors, and highlights the need for a multidisciplinary approach. © 2025, Farname Inc. All rights reserved.