Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications

Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications Publisher

Malekzad H¹ ; Sahandi Zangabad P^{2, 3, 8} ; Mirshekari H^{4, 5} ; Karimi M^{1, 6, 7} ; Hamblin MR¹

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1. Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, P.O. Box 14665-354, Tehran, Iran
2. Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, 02114, MA, United States
3. Department of Dermatology, Harvard Medical School, Boston, 02115, MA, United States
4. Division of Health Sciences and Technology, Harvard-MIT, Cambridge, 02139, MA, United States
5. Faculty of Chemistry, Kharazmi University, P.O. Box 15719-14911, Tehran, Iran
6. Advanced Nanobiotechnology and Nanomedicine Research Group (ANNRG), Iran University of Medical Sciences, Tehran, Iran
7. Research Center for Pharmaceutical Nanotechnology (RCPN), Tabriz University of Medical Science (TUOMS), Tabriz, Iran
8. Department of Materials Science and Engineering, Sharif University of Technology, P.O. Box 11365-9466, Tehran, 14588, Iran

Source: Nanotechnology Reviews Published:2017

Abstract

The aim of this review is to cover advances in noble metal nanoparticle (MNP)-based biosensors and to outline the principles and main functions of MNPs in different classes of biosensors according to the transduction methods employed. The important biorecognition elements are enzymes, antibodies, aptamers, DNA sequences, and whole cells. The main readouts are electrochemical (amperometric and voltametric), optical (surface plasmon resonance, colorimetric, chemiluminescence, photoelectrochemical, etc.) and piezoelectric. MNPs have received attention for applications in biosensing due to their fascinating properties. These properties include a large surface area that enhances biorecognizers and receptor immobilization, good ability for reaction catalysis and electron transfer, and good biocompatibility. MNPs can be used alone and in combination with other classes of nanostructures. MNP-based sensors can lead to significant signal amplification, higher sensitivity, and great improvements in the detection and quantification of biomolecules and different ions. Some recent examples of biomolecular sensors using MNPs are given, and the effects of structure, shape, and other physical properties of noble MNPs and nanohybrids in biosensor performance are discussed. © 2017 Walter de Gruyter GmbH, Berlin/Boston 2017.

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Style	Citing Format
MLA	Malekzad H, et al.. "Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications." Nanotechnology Reviews, vol. 6, no. 3, 2017, pp. 301-329.
APA	Malekzad H, Sahandi Zangabad P, Mirshekari H, Karimi M, Hamblin MR (2017). Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications. Nanotechnology Reviews, 6(3), 301-329.
Chicago	Malekzad H, Sahandi Zangabad P, Mirshekari H, Karimi M, Hamblin MR. "Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications." Nanotechnology Reviews 6, no. 3 (2017): 301-329.
Harvard	Malekzad H et al. (2017) 'Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications', Nanotechnology Reviews, 6(3), pp. 301-329.
Vancouver	Malekzad H, Sahandi Zangabad P, Mirshekari H, Karimi M, Hamblin MR. Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications. Nanotechnology Reviews. 2017;6(3):301-329.
BibTex	@article{ author = {Malekzad H and Sahandi Zangabad P and Mirshekari H and Karimi M and Hamblin MR}, title = {Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications}, journal = {Nanotechnology Reviews}, volume = {6}, number = {3}, pages = {301-329}, year = {2017} }
RIS	TY - JOUR AU - Malekzad H AU - Sahandi Zangabad P AU - Mirshekari H AU - Karimi M AU - Hamblin MR TI - Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications JO - Nanotechnology Reviews VL - 6 IS - 3 SP - 301 EP - 329 PY - 2017 ER -

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