Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code

Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code Publisher

Joya M^{1, 2} ; Nedaie HA¹ ; Geraily G¹ ; Ghorbani M³ ; Sheikhzadeh P^{1, 4} ; Arani MN⁵

Show Affiliations

1. Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2. Radiology Department, Kabul University of Medical Sciences, Kabul, Afghanistan
3. Biomedical Engineering and Medical Physics Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4. Department of Nuclear Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
5. The Advocate Center for Clinical Research, Ayatollah Yasrebi Hospital, Kashan, Iran

Source: Heliyon Published:2022

Abstract

Purpose: This study aims to validate the dosimetric characteristics of High Dose Rate (HDR) 60Co source (Co0.A86 model) using GATE Geant4-based Monte Carlo code. According to the recommendation of the American Association of Physicists in Medicine (AAPM) task group report number 43, the dosimetric parameters of a new brachytherapy source should be verified either experimentally or by Monte Carlo calculation before clinical applications. The validated 60Co source in this study will be used for the simulation of intensity-modulated brachytherapy (IMBT) of vaginal cancer using the same GATE Geant4-based Monte Carlo code in the future. Materials and methods: GATE (version 9.0) simulation code was used to model and calculate the required TG-43U1 dosimetric data of the 60Co HDR source. DoseActors were defined for calculation of dose rate constant, radial dose function, and anisotropy function in a water phantom with an 80 cm radius. Results: The dose rate constant was obtained as 1.070±0.008cGy.h−1.U−1 which shows a relative difference of 2.01% compared to the consensus value, 1.092 cGy.h−1.U−1. The calculated results of anisotropy and radial dose functions starting from 0.1 cm to 10 cm around the source showed excellent agreement with the results of published studies. The mean variation of the radial dose and anisotropy functions values from the consensus data were 1% and 0.9% respectively. Conclusion: Findings from this investigation revealed that the validation of the HDR 60Co source is feasible by the GATE Geant4-based Monte Carlo code. As a result, the GATE Monte Carlo code can be used for the verification of the brachytherapy treatment planning system. © 2022

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Experts (# of related papers)

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Ghazaleh Geraily (3)

Hassan Ali Nedaie (2)

Style	Citing Format
MLA	Joya M, et al.. "Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code." Heliyon, vol. 8, no. 3, 2022, pp. -.
APA	Joya M, Nedaie HA, Geraily G, Ghorbani M, Sheikhzadeh P, Arani MN (2022). Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code. Heliyon, 8(3), -.
Chicago	Joya M, Nedaie HA, Geraily G, Ghorbani M, Sheikhzadeh P, Arani MN. "Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code." Heliyon 8, no. 3 (2022): -.
Harvard	Joya M et al. (2022) 'Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code', Heliyon, 8(3), pp. -.
Vancouver	Joya M, Nedaie HA, Geraily G, Ghorbani M, Sheikhzadeh P, Arani MN. Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code. Heliyon. 2022;8(3):-.
BibTex	@article{ author = {Joya M and Nedaie HA and Geraily G and Ghorbani M and Sheikhzadeh P and Arani MN}, title = {Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code}, journal = {Heliyon}, volume = {8}, number = {3}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Joya M AU - Nedaie HA AU - Geraily G AU - Ghorbani M AU - Sheikhzadeh P AU - Arani MN TI - Bebig 60Co Hdr Brachytherapy Source Dosimetric Parameters Validation Using Gate Geant4-Based Simulation Code JO - Heliyon VL - 8 IS - 3 SP - EP - PY - 2022 ER -

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