Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples

Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples Publisher

Torfi F¹ ; Kamani F¹ ; Tavakolian S² ; Hosseini MR¹ ; Nazar NSB³ ; Alvandi S⁴ ; Faghihloo E²

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1. Surgical Department, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2. Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3. Physical Medicine and Rehabilitation Department, Medical and Educational Center of Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4. Imam Khomeini Hospital, Tehran University of Medical Science, Tehran, Iran

Source: Gene Reports Published:2021

Abstract

Introduction: Despite advances in science and technology, breast cancer is the fifth most common cancer in Iran. Previous studies have reported that there is a concrete relationship between this type of cancer and different kinds of risk factors, especially infection diseases. Among various kinds of infectious risk factors, much attention has been given to Herpesviridae. As the prevalence of EBV and CMV in patients suffering from breast cancer is not clear, in this study we evaluated these two viruses using PCR. Material & methods: The phenol-chloroform protocol was used to extract DNA. Then, to evaluate the EBV and CMV infections, PCR analysis was performed to assess the presence of EBNA-1 and Glycoprotein gB genes, respectively. Results: PCR illustrated two EBV positive samples among cancerous tissues while all normal adjacent tissues were EBV negative. Moreover, we did not detect any CMV positive samples. Conclusion: According to the present study, there is no association between EBV and CMV with breast cancer in Iranian women; however, further investigation was required. © 2021

2. The Role of Epstein-Barr Virus-Expressed Genes in Breast Cancer Development, Breast Journal (2020)

3. Prevalence of Hsv, Varicella-Zoster, Cmv, Ebv and Hpv in the Oral Cavity and the Larynx Carcinoma in Iran, Future Virology (2021)

Style	Citing Format
MLA	Torfi F, et al.. "Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples." Gene Reports, vol. 24, no. , 2021, pp. -.
APA	Torfi F, Kamani F, Tavakolian S, Hosseini MR, Nazar NSB, Alvandi S, Faghihloo E (2021). Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples. Gene Reports, 24(), -.
Chicago	Torfi F, Kamani F, Tavakolian S, Hosseini MR, Nazar NSB, Alvandi S, Faghihloo E. "Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples." Gene Reports 24, no. (2021): -.
Harvard	Torfi F et al. (2021) 'Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples', Gene Reports, 24(), pp. -.
Vancouver	Torfi F, Kamani F, Tavakolian S, Hosseini MR, Nazar NSB, Alvandi S, et al.. Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples. Gene Reports. 2021;24():-.
BibTex	@article{ author = {Torfi F and Kamani F and Tavakolian S and Hosseini MR and Nazar NSB and Alvandi S and Faghihloo E}, title = {Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples}, journal = {Gene Reports}, volume = {24}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Torfi F AU - Kamani F AU - Tavakolian S AU - Hosseini MR AU - Nazar NSB AU - Alvandi S AU - Faghihloo E TI - Evaluation of Association Between the Frequency of Epstein–Barr Virus and Cytomegalovirus Infection in Healthy and Tumoral Breast Samples JO - Gene Reports VL - 24 IS - SP - EP - PY - 2021 ER -

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