Nanotoxicology: An Integrative Environmental Challenge Publisher



Hassan DS¹ ; Hasary HJM²
Source: Al-Rafidain Journal of Medical Sciences Published:2022

Abstract

A contemporary and expanding area of toxicology research is nanotoxicology. It focuses on evaluating the toxicological characteristics of nanoparticles (NPs) in order to determine whether and how much of a risk to society or the environment they pose. Fundamental characteristics of nanoparticles (consisting of shape, size, surface charge, surface area, solubility/dissolution, coating and crystal structure), in addition to coincidental aspects (like climate, pH, salinity, ionic potency, and organic material), generally impact on NP attitude, circumstance, and movement, and basically toxicity. The processes underpinning nanomaterials' (NMs) toxicity have recently been intensively researched. One such mechanism is the toxicity of reactive oxygen species (ROS). Excessive production of ROS causes oxidative stress, which causes cells to lose their capacity to sustain normal redox-regulated processes. This review consists of details referring to physical and chemical characteristics of nanomaterials and properties for convenient toxicological assessment, disclosure, and coincidental transport, fate, and genotoxic effects. © 2022 The Author(s). Published by Al-Rafidain University College under the CC BY-NC-ND license.