A Review of the Applications of Biochemicals Interference in Medical Imaging With the Synthesis of Contrast Nanoparticles and Marker Design (Probe) Publisher



Nouri Z¹ Show Affiliations
Source: Biointerface Research in Applied Chemistry Published:2022

Abstract

One of the main focuses in diagnostic medicine is molecular imaging. Nanoparticles allow us to image different components of a high-contrast molecule efficiently. In this study, various factors that should be considered when synthesizing contrast nanoparticles are discussed. Some of the most important examples are highlighted. This research has been done theoretically and in terms of content analysis method (Content Analysis) by searching for keywords nanotechnology, molecular imaging, drug delivery methods, gene therapy, and contrast nanoparticles in google, PubMed, Science direct, scholar, and Scopus websites. After the search, ten articles were selected from the obtained articles, and this article was written based on them. Most of the report’s nanoparticles produce new contrast agents, especially molecular imaging and cellular processes detection. Have been taken. The advantages of using these nanoparticles are the ability to produce high contrast, ease of integration of multiple properties, long circulation time in the blood, and the ability to carry high-volume materials (such as drugs). The basics and nanoparticle production methods have grown and expanded over the years, so more complex examples of nanoscale contrast agents such as paramagnetic particles, macrophages with quantum dots, quantum dots, machines that can make matter Atomic and molecular parts have been reported. MRI of microemulsions has also been used to examine blood vessels and deliver medication. The use of contrast nanoparticles provides more details about the processes of a disease and its effects. The fabrication of these materials has improved dramatically over the past decade by creating various functions in them. However, there are many areas for biocompatibility, efficacy, specificity, and diagnosis of further diseases. In general, contrast nanoparticles can be synthesized for a specific function, with specific properties to perform a specific program. © 2021 by the authors.