Gut Microbiome in Multiple Sclerosis-Related Cognitive Impairment Publisher Pubmed



Ghadiri F¹ ; Ebadi Z¹ ; Asadollahzadeh E¹ ; Naser Moghadasi A¹
Source: Multiple Sclerosis and Related Disorders Published:2022

Abstract

Cognition is one of the most evaluated neurologic subjects with which the gut microbiome is supposed to be associated. Cognitive impairment is a prevalent finding in patients with multiple sclerosis (MS). Here, we are about to study the current evidence on the effect of gut microbiota on cognition and MS. Although no direct evidence is in hand, putting all indirect research together, one could think of the hypothetical benefit of brain-gut axis interventions (possibly diet changes, probiotic administration, microbiota transplant) to solve the drastic problem of cognitive impairment in MS. Hence, researchers are encouraged to scan this horizon in order to fill the knowledge gaps in the field. © 2022 Elsevier B.V.