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Bioactive Glasses Entering the Mainstream Publisher Pubmed



Kargozar S1 ; Baino F2 ; Hamzehlou S3, 4 ; Hill RG5 ; Mozafari M6, 7, 8
Authors
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Authors Affiliations
  1. 1. Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, PO Box 917794-8564, Mashhad, Iran
  2. 2. Institute of Materials Physics and Engineering, Department of Applied Science and Technology (DISAT), Politecnico di Torino, PO Box 10129, Torino, Italy
  3. 3. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, PO Box 14155-6447, Tehran, Iran
  4. 4. Medical Genetics Network (MeGeNe), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  5. 5. Unit of Dental Physical Sciences, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Mile End Road, London, E1 4NS, United Kingdom
  6. 6. Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), PO Box 14155-4777, Tehran, Iran
  7. 7. Cellular and Molecular Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran
  8. 8. Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran

Source: Drug Discovery Today Published:2018


Abstract

Over the past decade, the extended research on bioactive glasses (BGs) has drastically grown because of their bioactive nature and unique ability to deliver therapeutics in tissue engineering, regenerative medicine and even cancer research. These strategies mostly rely on the inherent potential of BGs regarding bonding to the living tissues and accelerating the healing process. All the possibilities are strongly associated with releasing various therapeutic ions from the BG structures into the biological environment. Additionally, some types of glasses [i.e., mesoporous bioactive glasses (MBGs)] can serve as suitable platforms for the delivery of various small molecules and pharmaceutical agents. This class of biomaterials is recognised as a highly versatile delivery system, playing a crucial part in the future of medicine. © 2018 Elsevier Ltd
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