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Efficacy of Phospholipidated Curcumin in Nonalcoholic Fatty Liver Disease: A Clinical Study Publisher Pubmed



Panahi Y1 ; Kianpour P2 ; Mohtashami R3 ; Soflaei SS4 ; Sahebkar A5, 6, 7
Authors

Source: Journal of Asian Natural Products Research Published:2019


Abstract

Curcumin is a safe and dietary phytochemical that can improve different pathophysiologic features of non-alcoholic fatty liver disease (NAFLD). Here, we investigated the efficacy of phospholipidated curcumin supplementation in NAFLD patients. In this single-arm study, 36 patients were recruited. Each patient received three capsules a day (each containing 500 mg of phospholipidated curcumin [overall content of curcuminoids per capsule: 100 mg]) for a period of 8 weeks. The results indicated that phospholipidated curcumin supplementation reduced NAFLD severity and ameliorated ultrasonographic and biochemical measures (including liver transaminases and lipid profile) associated with disease progression. © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.
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