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Worldwide Network for Blood and Marrow Transplantation Recommendations for Establishing a Hematopoietic Stem Cell Transplantation Program in Countries With Limited Resources, Part Ii: Clinical, Technical, and Socioeconomic Considerations Publisher Pubmed



Aljurf M1 ; Weisdorf D2 ; Hashmi S1, 3 ; Nassar A4 ; Gluckman E5 ; Mohty M6 ; Rizzo D7 ; Pasquini M7 ; Hamadani M7 ; Saber W7 ; Hari P7 ; Kharfandabaja M8 ; Majhail N9 ; Gerges U10 Show All Authors
Authors
  1. Aljurf M1
  2. Weisdorf D2
  3. Hashmi S1, 3
  4. Nassar A4
  5. Gluckman E5
  6. Mohty M6
  7. Rizzo D7
  8. Pasquini M7
  9. Hamadani M7
  10. Saber W7
  11. Hari P7
  12. Kharfandabaja M8
  13. Majhail N9
  14. Gerges U10
  15. Hamidieh AA11
  16. Hussain F1
  17. Elhaddad A4
  18. Mahmoud HK4
  19. Tbakhi A12
  20. Othman TB13
  21. Hamladji RM14
  22. Bekadja MA15
  23. Ahmed P16
  24. Bazarbachi A17
  25. Adil S18
  26. Alkindi S19
  27. Ladeb S13
  28. Dennison D19
  29. Patel M20
  30. Lu P21
  31. Quessar AE22
  32. Okamoto S23
  33. Atsuta Y24
  34. Alhejazi A25
  35. Ayas MF1
  36. Ahmed SO1
  37. Novitzky N26
  38. Srivastava A27
  39. Seber A28
  40. Solh HE1
  41. Ghavamzadeh A11
  42. Confer D7
  43. Kodera Y29
  44. Hildegard G30
  45. Szer J31
  46. Horowitz MM7
  47. Niederwieser D29, 32
Show Affiliations
Authors Affiliations
  1. 1. Hematology Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
  2. 2. University of Minnesota, Minneapolis, MN, United States
  3. 3. Department of Medicine, Mayo Clinic, Rochester, MN, United States
  4. 4. National Cancer Institute, Cairo University, Cairo, Egypt
  5. 5. Eurocord Hopital Saint-Louis and University Paris Diderot, Paris, France
  6. 6. Hopital Saint-Antoine, Sorbonne University, Paris, France
  7. 7. Center for International Blood and Marrow Transplant Research, Milwaukee, WI, United States
  8. 8. Department of Medicine, Division of Hematology-Oncology and Blood and Marrow Transplantation program, Mayo Clinic, Jacksonville, FL, United States
  9. 9. Blood and Marrow Transplant Program, Cleveland Clinic, Cleveland, OH, United States
  10. 10. Hematologic Malignancies & Bone Marrow Transplant, Department of Medicial Oncology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, United States
  11. 11. Hematology, Oncology and SCT Research Center, Tehran University of Medical Sciences, Tehran, Iran
  12. 12. King Hussein Cancer Center, Amman, Jordan
  13. 13. Center National de Greffe de Moelle Osseuse de Tunis, Tunis, Tunisia
  14. 14. Pierre and Marie Curie Center, Algiers, Algeria
  15. 15. University Hospital Establishment 1st Nov, Oran, Algeria
  16. 16. Armed Forces Institute of Transplantation, Rawalpindi, Pakistan
  17. 17. Department of Hematology/Oncology, American University of Beirut Medical Center, Beirut, Lebanon
  18. 18. Aga Khan University Hospital, Karachi, Pakistan
  19. 19. Sultan Qaboos University Hospital, Muscat, Oman
  20. 20. University of the Witwatersrand, Johannesburg, South Africa
  21. 21. Hebei Yanda Ludaopei Hospital, Langfang, China
  22. 22. Hopital 20 Aout, Casablanca, Morocco
  23. 23. Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan
  24. 24. Keio University School of Medicine, Tokyo, Japan
  25. 25. King Abdulaziz Medical City, NGHA, Riyadh, Saudi Arabia
  26. 26. African Blood & Marrow Transplantation Society, South Africa
  27. 27. Christian Medical College and Hospital, Bagayam, Vellore, India
  28. 28. Instituto de Oncologia Pediatrica, Sao Paulo, Brazil
  29. 29. Center for Hematopoietic Stem Cell Transplantation, Aichi Medical University Hospital, Nagakute, Japan
  30. 30. Medical University of Graz, Graz, Austria
  31. 31. Department of Clinical Haematology, Royal Melbourne Hospital, Melbourne, Australia
  32. 32. Department of Hematology and Medical Oncology, University Hospital, Leipzig, Germany

Source: Biology of Blood and Marrow Transplantation Published:2019


Abstract

The development of hematopoietic stem cell transplantation (HSCT) programs can face significant challenges in most developing countries because such endeavors must compete with other government health care priorities, including the delivery of basic services. Although this is may be a limiting factor, these countries should prioritize development of the needed expertise to offer state-of-the-art treatments, including transplantation, by providing financial, technological, legal, ethical, and other needed support. This would prove beneficial in providing successful programs customized to the needs of their population and potentially provide long-term cost savings by circumventing the need for their citizens to seek care abroad. The costs of establishing an HSCT program and the costs of the HSCT procedure itself can be substantial barriers in developing countries. In addition, socioeconomic factors intrinsic to specific countries can influence access to HSCT, patient eligibility for HSCT, and timely utilization of HSCT center capabilities. This report describes recommendations from the Worldwide Network for Blood and Marrow Transplantation for establishing HSCT programs, with a specific focus on developing countries, and identifies challenges and opportunities for providing this specialized procedure in resource-constrained settings. © 2019 American Society for Transplantation and Cellular Therapy