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Sulfur- and Dabco-Promoted Reaction Between Alkylidene Rhodanines and Isothiocyanates: Access to Aminoalkylidene Rhodanines Publisher



Farajpour B1 ; Alizadeh GB1 ; Majedi S2 ; Moradkhani F3 ; Majedi S2 ; Notash B5 ; Hosseindoust B1 ; Shiri M1
Authors

Source: ACS Omega Published:2024


Abstract

In this work, an efficient sulfur- and DABCO-promoted reaction for the synthesis of aminoalkylidene rhodanines from available alkylidene rhodanines and isothiocyanates is reported. A tandem process including sulfurative annulation/ring-opening by liberation of a CS2 molecule/olefination allows the synthesis of aminoalkylidene rhodanines with acceptable functional group tolerance. Chemo- and stereoselectivity, operational simplicity, and synthetically useful yields are some highlighted advantages of these transformations. © 2024 The Authors. Published by American Chemical Society.