Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction

Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction Publisher

Yazzaf R² ; Adib M² ; Mahdavi M¹

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1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
2. School of Chemistry, College of Science, University of Tehran, PO Box, Tehran, 14155-6455, Iran

Source: ChemistrySelect Published:2023

Abstract

A library of pyrazino[1,2-a]indoles has been synthesized via direct amidation and alkyne hydroamination reactions of the molecule produced by indole-2-carboxylic acid and propargyl bromide. The noteworthy features of the present strategy are short reaction time, excellent yields and a broad substrate scope. This cascade reaction also occurred under transition metal-free and ambient conditions as well as operational simplicity. © 2023 Wiley-VCH GmbH.

Style	Citing Format
MLA	Yazzaf R, Adib M, Mahdavi M. "Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction." ChemistrySelect, vol. 8, no. 15, 2023, pp. -.
APA	Yazzaf R, Adib M, Mahdavi M (2023). Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction. ChemistrySelect, 8(15), -.
Chicago	Yazzaf R, Adib M, Mahdavi M. "Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction." ChemistrySelect 8, no. 15 (2023): -.
Harvard	Yazzaf R, Adib M, Mahdavi M (2023) 'Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction', ChemistrySelect, 8(15), pp. -.
Vancouver	Yazzaf R, Adib M, Mahdavi M. Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction. ChemistrySelect. 2023;8(15):-.
BibTex	@article{ author = {Yazzaf R and Adib M and Mahdavi M}, title = {Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction}, journal = {ChemistrySelect}, volume = {8}, number = {15}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Yazzaf R AU - Adib M AU - Mahdavi M TI - Potassium T-Butoxide-Promoted Metal-Free Synthesis of Pyrazino[1,2-A]Indoles Via Direct Amidation and Intramolecular Hydroamination Reaction JO - ChemistrySelect VL - 8 IS - 15 SP - EP - PY - 2023 ER -

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