Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan

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Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan Pubmed

Hashemipour M¹ ; Amini M¹ ; Talaie M¹ ; Kelishadi R¹ ; Hovespian S¹ ; Iranpour R¹ ; Salek M¹ ; Haghigh S¹ ; Khatibi KH¹

Source: Eastern Mediterranean Health Journal Published:2007

Abstract

We determined the prevalence of congenital hypothyroidism and the rate of consanguinity among parents of hypothyroid neonates among 93 381 neonates born in 17 hospitals in Isfahan from May 2002 to April 2005. Serum thyroxine (T4) and thyroid stimulating hormone (TSH) levels were measured on the 3rd-7th day of birth and neonates with abnormal levels were recalled and the levels reassessed. Those with TSH ≥ 10 mIU/L and T4 < 6.5 μg/dL on the second assay were considered hypothyroid. In all, 1038 neonates were recalled and 274 were diagnosed as hypothyroid. There was a significant association between parental consanguinity and congenital hypothyroidism (P = 0.006); congenital hypothyroidism was commoner in neonates with 1st cousin parental consanguinity than 2nd cousin parental consanguinity (P = 0.008).

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Style	Citing Format
MLA	Hashemipour M, et al.. "Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan." Eastern Mediterranean Health Journal, vol. 13, no. 3, 2007, pp. 567-574.
APA	Hashemipour M, Amini M, Talaie M, Kelishadi R, Hovespian S, Iranpour R, Salek M, Haghigh S, Khatibi KH (2007). Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan. Eastern Mediterranean Health Journal, 13(3), 567-574.
Chicago	Hashemipour M, Amini M, Talaie M, Kelishadi R, Hovespian S, Iranpour R, Salek M, Haghigh S, Khatibi KH. "Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan." Eastern Mediterranean Health Journal 13, no. 3 (2007): 567-574.
Harvard	Hashemipour M et al. (2007) 'Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan', Eastern Mediterranean Health Journal, 13(3), pp. 567-574.
Vancouver	Hashemipour M, Amini M, Talaie M, Kelishadi R, Hovespian S, Iranpour R, et al.. Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan. Eastern Mediterranean Health Journal. 2007;13(3):567-574.
BibTex	@article{ author = {Hashemipour M and Amini M and Talaie M and Kelishadi R and Hovespian S and Iranpour R and Salek M and Haghigh S and Khatibi KH}, title = {Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan}, journal = {Eastern Mediterranean Health Journal}, volume = {13}, number = {3}, pages = {567-574}, year = {2007} }
RIS	TY - JOUR AU - Hashemipour M AU - Amini M AU - Talaie M AU - Kelishadi R AU - Hovespian S AU - Iranpour R AU - Salek M AU - Haghigh S AU - Khatibi KH TI - Parental Consanguinity Among Parents of Neonates With Congenital Hypothyroidism in Isfahan JO - Eastern Mediterranean Health Journal VL - 13 IS - 3 SP - 567 EP - 574 PY - 2007 ER -

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