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Propolis As an Adjunctive Therapy for Treatment of Uncomplicated Cystitis in Women: A Randomized Double-Blind Placebo-Controlled Trial Publisher Pubmed

Summary: Propolis with ciprofloxacin reduces urinary symptoms in women with cystitis, but more studies needed. #Cystitis #HerbalTherapy

Shekari M1 ; Hadi A2 ; Daabo HMA3 ; Allahyari ZH4 ; Hjazi A5 ; Rafie N6 ; Heidari M7
Authors

Source: Phytotherapy Research Published:2024


Abstract

The current research is designed to investigate the effect of propolis supplementation on the clinical manifestations in women suffering from uncomplicated cystitis. In this randomized double-blind, placebo-controlled trial, 120 women with uncomplicated cystitis were selected and randomly assigned into two groups to receive two 500 mg capsules of propolis or placebo daily for 7 days along with ciprofloxacin (250 mg). Clinical symptoms including hematuria, urinary frequency, dysuria, suprapubic pain, and urgency, as well as bacteriuria, were assessed before and after the intervention. After supplementation, participants in the intervention group had significantly fewer days of urinary frequency (p < 0.001), dysuria (p = 0.005), and urgency (p = 0.03). However, there was no significant difference between the two groups regarding hematuria and suprapubic pain (p > 0.05). Furthermore, the severity of bacteriuria decreased significantly in both groups. In conclusion, it seems that propolis supplementation in women with uncomplicated cystitis could improve urinary frequency, dysuria, and urgency. However, further clinical trials should be conducted to fully understand the effects of propolis in women suffering from uncomplicated cystitis. © 2023 John Wiley & Sons Ltd.
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