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In Vitro Antifungal Activity of Iranian Propolis Against Microsporum Canis, M. Gypseum and M. Nanum Publisher



Mannani R1 ; Zia M1 ; Mahmoudi M2 ; Manshaei M3
Authors
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Authors Affiliations
  1. 1. Department of Basic Sciences, Khorasgan (Isfahan) Branch, Islamic Azad University, Iran
  2. 2. Health Education and Research Center, Tehran Medical Sciences University, Tehran, Iran
  3. 3. Animal Lab of Dental Research Center, School of Dentistry, Medical Science University of Isfahan, Isfahan, Iran

Source: Journal of Biologically Active Products from Nature Published:2012


Abstract

Propolis is known for its biological, antibacterial, antifungal, and healing properties. Antifungal activity was tested with the ethanolic extract of propolis against 21 strains of Microsporum canis, M. gypseum, and M. nanum. The ethanolic extract of propolis showed antifungal activity against all the 3 species. The minimal inhibitory concentrations (MICs) of the ethanolic extract of propolis were 0.2µL/mL for M. gypseum, 0.05µL/mL for M. nanum, and 0.025µL/mL for M. canis. It seems that Iranian propolis has pharmacological value as a natural product and it is necessary for further investigation into propolis as a potentially useful agent for the treatment of dermatophytosis. The aim of present study was to identify inhibitory effect of Iranian propolis against abovementioned species of Microsporum. © 2012, Copyright Har Krishan Bhalla & Sons.
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