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Synthesize and Characterization of a Novel Cadmium Selenide Nanoparticle With Iron Precursor Applicable in Hyperthermia of Cancer Cells



Jafaripour N1 ; Omidvar H1 ; Sabersamandari S2 ; Mohammadi R3 ; Foroushani RS4 ; Moghadas BK3 ; Soleimani M5 ; Noshadi B6 ; Khandan A2
Authors
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Authors Affiliations
  1. 1. Faculty of Materials Engineering, Amirkabir University of Technology, Tehran, Iran
  2. 2. New Technologies Research Center, Amirkabir University of Technology, Tehran, Iran
  3. 3. Department of Chemical Engineering, Shiraz Branch, Islamic Azad University, Shiraz, Iran
  4. 4. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Biomedical Engineering Department, Islamic Azad University Science and Research Branch, Tehran, Iran
  6. 6. Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eastern Mediterranean University, via Mersin 10, Famagusta, North Cyprus, TR-99628, Turkey

Source: International Journal of Nanoscience and Nanotechnology Published:2021

Abstract

Many researchers have considered the idea of using heat to shrink cancer cells and treat cancer. However, efforts in recent years have led to creating novel material more practical in clinical application. The main reason for the synthesis and producing these materials is to raise the temperature in the right place so that healthy cells around the cancerous tissue are not harmed. Nowadays, this can be partly achievable with new devices and methods. Also, cadmium selenide (CdSe) nanoparticles with zinc selenide (ZnS) coating for special optical properties were investigated in this work. The CdSe nanoparticles have a wide application in biomedical engineering, including detecting cancer tumors and hyperthermia. There are various methods for synthesizing CdSe nanoparticles, such as precipitation, wet chemistry, mechanical activation, and mechanochemical technique. In this study, we have tried to use an economical method to control Cd ions’ toxicity. After fabricating the nanoparticles, vibrating sample magnetometer (VSM), and hyperthermia analyses (HT), X-ray diffraction (XRD), and scanning electron microscopy (SEM) technique were performed to characterize the magnetization, thermal changes versus time, phase, and morphology of the synthesized nanoparticles. The obtained results indicated that the CdSe successfully synthesized using chemical segmentation for biomaterials applications. © 2021. All Rights Reserved.
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