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Implants With or Without Leukocyte- and Platelet-Rich Fibrin (L-Prf): A Systematic Review on Dental Implant Stability Publisher



Damsaz M1 ; Rahmani F2 ; Arzani S3 ; Jafari S4 ; Farzanegan P5 ; Amirzadeiranaq MH6 ; Keyhan SO7, 8, 9, 10, 11
Authors
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Authors Affiliations
  1. 1. iFACE Oral and Maxillofacial Surgery Academy, Istanbul, Turkiye
  2. 2. Shiraz, Iran
  3. 3. Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. RUDN University (Poccийcкий yнивepcитeт дpyжбы нapoдoв), Moscow, Russian Federation
  5. 5. Babol University of Medical Sciences, Babol, Iran
  6. 6. Department of Research, Arka Education and Clinical Research Consultants, Tehran, Iran
  7. 7. Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung, South Korea
  8. 8. Department of Oral and Maxillofacial Surgery, University of Florida, College of Medicine, Jacksonville, FL, United States
  9. 9. Maxillofacial Surgery and Implantology and Biomaterial Research Foundation, Istanbul, Turkiye
  10. 10. Iface Academy, Istanbul, Turkiye
  11. 11. Isfahan, Iran

Source: Journal of Maxillofacial and Oral Surgery Published:2025


Abstract

Background: To examine the impact of applying leukocyte- and platelet-rich fibrin (L-PRF) on the stability of dental implants using implant stability quotient (ISQ) measurements. Methods: A systematic search of the main databases was conducted to source the literature. Studies that met the established inclusion and exclusion criteria were selected for this review. The focus was solely on randomized controlled trials (RCTs) and controlled clinical trials (CCTs). Results: After conducting a comprehensive search, a total of 1984 studies were identified. Following evaluation based on our inclusion and exclusion criteria, a refined selection of 7 studies was chosen for detailed review in this analysis. Conclusions: Our findings indicate that the use of leukocyte- and platelet-rich fibrin (L-PRF) may enhance the stability of implants following surgical procedures. This suggests that L-PRF may accelerate the healing process, reduce the loading time, and improve outcomes for patients undergoing implant surgery, potentially reducing the risk of implant failures and complications. © The Association of Oral and Maxillofacial Surgeons of India 2025.
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