Can Berberine Serve As a New Therapy for Parkinson’S Disease?

Can Berberine Serve As a New Therapy for Parkinson’S Disease? Publisher Pubmed

Dadgostar E^{1, 2} ; Moghanlou M³ ; Parvaresh M⁴ ; Mohammadi S⁵ ; Khandan M⁶ ; Aschner M⁷ ; Mirzaei H⁸ ; Tamtaji OR^{9, 10}

Show Affiliations

1. Behavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2. Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
3. Department of Psychiatry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4. Department of Physical Medicine and Rehabilitation, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran
5. Anatomical Science Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran
6. Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran
7. Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, 10461, NY, United States
8. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran
9. Electrophysiology Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
10. Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Neurotoxicity Research Published:2022

Abstract

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by dopaminergic neurodegeneration and deposition of alpha-synuclein. Mechanisms associated with PD etiology include oxidative stress, apoptosis, autophagy, and abnormalities in neurotransmission, to name a few. Drugs used to treat PD have shown significant limitations in their efficacy. Therefore, recent focus has been placed on the potential of active plant ingredients as alternative, complementary, and efficient treatments. Berberine is an isoquinoline alkaloid that has shown promise as a pharmacological treatment in PD, given its ability to modulate several molecular pathway associated with the disease. Here, we review contemporary knowledge supporting the need to further characterize berberine as a potential treatment for PD. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Style	Citing Format
MLA	Dadgostar E, et al.. "Can Berberine Serve As a New Therapy for Parkinson’S Disease?." Neurotoxicity Research, vol. 40, no. 4, 2022, pp. 1096-1102.
APA	Dadgostar E, Moghanlou M, Parvaresh M, Mohammadi S, Khandan M, Aschner M, Mirzaei H, Tamtaji OR (2022). Can Berberine Serve As a New Therapy for Parkinson’S Disease?. Neurotoxicity Research, 40(4), 1096-1102.
Chicago	Dadgostar E, Moghanlou M, Parvaresh M, Mohammadi S, Khandan M, Aschner M, Mirzaei H, Tamtaji OR. "Can Berberine Serve As a New Therapy for Parkinson’S Disease?." Neurotoxicity Research 40, no. 4 (2022): 1096-1102.
Harvard	Dadgostar E et al. (2022) 'Can Berberine Serve As a New Therapy for Parkinson’S Disease?', Neurotoxicity Research, 40(4), pp. 1096-1102.
Vancouver	Dadgostar E, Moghanlou M, Parvaresh M, Mohammadi S, Khandan M, Aschner M, et al.. Can Berberine Serve As a New Therapy for Parkinson’S Disease?. Neurotoxicity Research. 2022;40(4):1096-1102.
BibTex	@article{ author = {Dadgostar E and Moghanlou M and Parvaresh M and Mohammadi S and Khandan M and Aschner M and Mirzaei H and Tamtaji OR}, title = {Can Berberine Serve As a New Therapy for Parkinson’S Disease?}, journal = {Neurotoxicity Research}, volume = {40}, number = {4}, pages = {1096-1102}, year = {2022} }
RIS	TY - JOUR AU - Dadgostar E AU - Moghanlou M AU - Parvaresh M AU - Mohammadi S AU - Khandan M AU - Aschner M AU - Mirzaei H AU - Tamtaji OR TI - Can Berberine Serve As a New Therapy for Parkinson’S Disease? JO - Neurotoxicity Research VL - 40 IS - 4 SP - 1096 EP - 1102 PY - 2022 ER -

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