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Efficacy of Photo Bio-Modulation Therapy for Pain Relief and Soft Tissue Wound Healing After Dental Implant Surgery: A Double-Blind Randomized Clinical Trial Publisher



Reza B1 ; Soheil N2 ; Ehsan B3 ; Kourosh S4 ; Reza F5, 6
Authors
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Authors Affiliations
  1. 1. Department of Periodontology, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Periodontology, School of Dentistry, Kashan University of Medical Sciences, Kashan, Iran
  3. 3. Department of Periodontology, School of Dentistry, International Campus, Iran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Periodontology, School of Dentistry, Shahrekord University of Medical Sciences, Shahrekord, Iran
  5. 5. Radiation Sciences Research Center, Laser Research Center in Medical Sciences, AJA University of Medical Sciences, Tehran, Iran
  6. 6. International Network for Photo Medicine and Photo Dynamic Therapy (INPMPDT), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Journal of Photochemistry and Photobiology Published:2021


Abstract

Objective: This study aimed to investigate the effect of photo bio-modulation therapy (PBMT) on pain relief and wound healing after dental implant surgery. Background data: Photo bio-modulation (PBM) has been used as a therapeutic method for the healing of wounds and controlling pain and inflammation. Materials and methods: In this clinical trial, 21 patients including 12 men and 9 women were selected based on inclusion criteria. Forty-two implants were placed in the posterior regions of both sides of the mandible. Immediately after the surgery, 660 nm and 810 nm diode laser beams with an energy density of 6 J/cm2 were concurrently irradiated on three sides of the implant regions, buccal, occlusal, and lingual sides. After 48 h both two lasers were applied to patients without irradiation, as placebo devices in the control side. The severity of patients’ pain was examined after 12, 24, 48, and 72 h based on a visual analog scale (VAS). Wound healing score was also determined at 3, 7, and 14 days postoperatively using the Likert scale from 0 to 4. The data were analyzed with SPSS. Statistical significance was set at α = 0.05. Results: The laser side exhibited a significant improvement in wound healing and pain relief at all the intervals compared to baseline (p < 0.05). Wilcoxon test showed that the wound healing score on the laser side at 3 (p < 0.001), 7 (p < 0.001), and 14 (p = 0.03) days was significantly better than that on the placebo side. Paired t-test showed that at all the intervals of 12 h (p < 0.008), 24 h (p < 0.04), 48 h (p < 0.008), and 72 h (p < 0.02), the mean pain score on the laser side was significantly lower than that on the placebo side. Conclusion: Given the limitations of this study, the results showed that PBM enhanced wound healing and decreased pain after dental implant surgery. © 2021 The Authors
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