Metal Nanoparticles and Carbohydrate Polymers Team up to Improve Biomedical Outcomes Publisher Pubmed



Falsafi SR¹ ; Topuz F² ; Bajer D³ ; Mohebi Z⁴ ; Shafieiuon M⁴ ; Heydari H⁵ ; Rawal S^{6, 7} ; Sathiyaseelan A⁸ ; Wang MH⁸ ; Khursheed R⁹ ; Enayati MH⁴ ; Rostamabadi H⁵
Source: Biomedicine and Pharmacotherapy Published:2023

Abstract

The convergence of carbohydrate polymers and metal nanoparticles (MNPs) holds great promise for biomedical applications. Researchers aim to exploit the capability of carbohydrate matrices to modulate the physicochemical properties of MNPs, promote their therapeutic efficiency, improve targeted drug delivery, and enhance their biocompatibility. Therefore, understanding various attributes of both carbohydrates and MNPs is the key to harnessing them for biomedical applications. The many distinct types of carbohydrate-MNP systems confer unique capabilities for drug delivery, wound healing, tissue engineering, cancer treatment, and even food packaging. Here, we introduce distinct physicochemical/biological properties of carbohydrates and MNPs, and discuss their potentials and shortcomings (alone and in combination) for biomedical applications. We then offer an overview on carbohydrate-MNP systems and how they can be utilized to improve biomedical outcomes. Last but not least, future perspectives toward the application of such systems are highlighted. © 2023 The Authors