Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices

Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices Publisher Pubmed

Falsafi SR¹ ; Bangar SP² ; Chaudhary V³ ; Hosseini E⁴ ; Mokhtari Z⁴ ; Karaca AC⁵ ; Samota MK⁶ ; Goswami D⁶ ; Krishnan V⁶ ; Askari G⁷ ; Rostamabadi H⁴

Show Affiliations

1. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran
2. Department of Food, Nutrition and Packaging Sciences, Clemson University, Clemson, 29634, United States
3. College of Dairy Science and Technology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Haryana, Hisar, India
4. Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran
5. Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Istanbul, 34469, Turkey
6. Division of Biochemistry, ICAR-Indian Agricultural Research Institute (IARI), New Delhi, 12, India
7. Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Carbohydrate Polymers Published:2022

Abstract

Controlled oral delivery of bioactive molecules remains a promising platform for the food and biomedical realm. Nonetheless, there are many bottlenecks to the efficient oral bioactive delivery that necessitates the development of advanced approaches. In recent years, prebiotic carbohydrates have drawn surging interest for targeted bioactive delivery due to their potential of multi-stimuli release mechanisms. Harnessing prebiotic-based vehicles confers novel possibilities for intact oral bioactive delivery, improving their bioavailability and efficacy. This critical review updates state of the art on progresses in oral delivery of natural active agents via prebiotic carbohydrates. We offer the latest advances concerning prebiotic-based vehicles (i.e., pH/time-dependent systems, enzyme-sensitive polymers, and colonic microbiota-dependent vehicles), emphasizing their key attributes to attaining controlled/targeted bioactive delivery to the intended locus. Finally, we discuss safety considerations, challenges, and future perspectives toward advances in the field. © 2022 Elsevier Ltd

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Hadis Rostamabadi (13)

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Style	Citing Format
MLA	Falsafi SR, et al.. "Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices." Carbohydrate Polymers, vol. 298, no. , 2022, pp. -.
APA	Falsafi SR, Bangar SP, Chaudhary V, Hosseini E, Mokhtari Z, Karaca AC, Samota MK, Goswami D, Krishnan V, Askari G, Rostamabadi H (2022). Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices. Carbohydrate Polymers, 298(), -.
Chicago	Falsafi SR, Bangar SP, Chaudhary V, Hosseini E, Mokhtari Z, Karaca AC, Samota MK, et al.. "Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices." Carbohydrate Polymers 298, no. (2022): -.
Harvard	Falsafi SR et al. (2022) 'Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices', Carbohydrate Polymers, 298(), pp. -.
Vancouver	Falsafi SR, Bangar SP, Chaudhary V, Hosseini E, Mokhtari Z, Karaca AC, et al.. Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices. Carbohydrate Polymers. 2022;298():-.
BibTex	@article{ author = {Falsafi SR and Bangar SP and Chaudhary V and Hosseini E and Mokhtari Z and Karaca AC and Samota MK and Goswami D and Krishnan V and Askari G and Rostamabadi H}, title = {Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices}, journal = {Carbohydrate Polymers}, volume = {298}, number = {}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Falsafi SR AU - Bangar SP AU - Chaudhary V AU - Hosseini E AU - Mokhtari Z AU - Karaca AC AU - Samota MK AU - Goswami D AU - Krishnan V AU - Askari G AU - Rostamabadi H TI - Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices JO - Carbohydrate Polymers VL - 298 IS - SP - EP - PY - 2022 ER -

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