Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Improvement of Biodegradability, Bioactivity, Mechanical Integrity and Cytocompatibility Behavior of Biodegradable Mg Based Orthopedic Implants Using Nanostructured Bredigite (Ca7mgsi4o16) Bioceramic Coated Via Asd/Epd Technique Publisher Pubmed



Razavi M1, 3, 4, 5 ; Fathi M1, 2 ; Savabi O3 ; Vashaee D5 ; Tayebi L4, 6
Authors

Source: Annals of Biomedical Engineering Published:2014


Abstract

This research explored the influence of surface modification of AZ91 Mg alloy on the biodegradation, bioactivity, mechanical integrity and cytocompatibility of the alloy. For this purpose, a nanostructured bredigite (Ca7MgSi4O16) ceramic coating was prepared on biodegradable AZ91 Mg alloy through anodic spark deposition and electrophoretic deposition method. The phase composition and surface morphology of the coated alloy were characterized by X-ray diffraction, scanning electron microscope and transmission electron microscope. The properties of samples were investigated by electrochemical measurements, immersion test, compression examination and cell culturing. The results showed that the degradation resistance, bioactivity, mechanical integrity and cytocompatibility of biodegradable Mg alloy were improved by the anodic spark deposition and electrophorretic deposition of the nanostructured bredigite coating. Therefore, the nanostructured bredigite ceramic coating is identified as a good coating for AZ91 Mg alloy for the purpose of making biodegradable metallic orthopedic implants. © 2014, Biomedical Engineering Society.
Other Related Docs
8. In Vivo Biocompatibility of Mg Implants Surface Modified by Nanostructured Merwinite/Peo, Journal of Materials Science: Materials in Medicine (2015)
11. Nanobiomaterials in Periodontal Tissue Engineering, Nanobiomaterials in Hard Tissue Engineering: Applications of Nanobiomaterials (2016)
14. Recent Advances on Akermanite Calcium-Silicate Ceramic for Biomedical Applications, International Journal of Applied Ceramic Technology (2021)