Tehran University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Co-Administration of Empagliflozin and Curcumin Attenuates the Development of Masld by Modulating Lipid Metabolism and Adipose Tissue Browning in Hfd-Fed C57bl/6J Mice
Omid Sabzevari
Omid Sabzevari

Professor of Pharmacology and Toxicology

Department Pharmacology Toxicology

School of Pharmacy

Toxicology and Poisoning Research Center

Tehran University of Medical Sciences

All Documents
1. Design and Evaluation of a Chalcone-Based Dimeric Scaffold Targeting Amyloid-Beta Plaques for Early Detection of Alzheimer’S Disease: Synthesis, Radiolabeling, in Vivo Studies, and Integrated Molecular Docking and Dynamics Simulation, Advanced Pharmaceutical Bulletin (2026)
2. Design, Synthesis, Molecular Docking, and Preclinical Evaluation of a New Radiolabeled Peg3-Linked Fapi Derivative for Fibroblast Activation Protein Targeting, Iranian Journal of Pharmaceutical Research (2026)
3. Study on the Liver-Protecting Properties of Ajuga Chamaecistus Ssp. Tomentella Against Acetaminophen-Induced Liver Damage in Rats, Traditional and Integrative Medicine (2026)
4. Antioxidant and Protective Effect of Ajuga Chamaecistus Ssp. Tomentella on Ccl4 -Induced Liver Toxicity in Rat, Traditional and Integrative Medicine (2025)
5. Biochemical and Histopathological Investigation of Nasturtium Officinale on Thyroid Function: An Experimental Study on Models of Hypothyroidism and Hyperthyroidism, Research Journal of Pharmacognosy (2025)
6. Effect of Diamorphine on Spatial Learning and Memory and Mitochondrial Function of Male Rat Brain, Iranian Journal of Pharmaceutical Research (2025)
7. Rolipram and Electrical Stimulation Synergistically Promote Neuronal Differentiation of Adipose-Derived Stromal Cells: An in Vitro Study, Stem Cell Reviews and Reports (2025)
8. The Effectiveness of Unfractionated Heparin Vs. Low Molecular Weight (Enoxaparin) in Acute Respiratory Distress Syndrom (Ards) and Metabolic Dysfunction: An Old Drug for New Indication!, BMC Immunology (2025)
9. 6-Gingerol Anti-Inflammatory and Antioxidant Properties Protect Against Heart and Liver Dysfunction in Rats With Sepsis, Pharmacological Research - Modern Chinese Medicine (2024)
10. Evaluation of the Hepatoprotective Effect of the Lumpy Bracket Medicinal Mushroom Trametes Gibbosa (Agaricomycetes) on Ccl4-Induced Liver Injury in Rats, International Journal of Medicinal Mushrooms (2024)
11. Liraglutide Alleviated Alpha-Pyrrolidinovalerophenone (Α-Pvp) Induced Cognitive Deficits in Rats by Modifying Brain Mitochondrial Impairment, European Journal of Pharmacology (2024)
12. Role of the Liver Capsule As a Traditional Medicine Formulation in the Treatment of Non-Alcoholic Fatty Liver Disease in Rats, Pharmaceutical Chemistry Journal (2024)
13. The Hepatically Less Toxic Metabolites of Aflatoxin B1 Versus the Parent Toxin: An in Vivo Bioremediation Study, Toxin Reviews (2024)
14. Acute and Subchronic Oral Toxicity Study of a Hepatoprotective Polyherbal Formulation ‘Liver Capsule’ in Rats, Pharmaceutical Chemistry Journal (2023)
15. Alpha Pyrrolidinovalerophenone (Α-Pvp) Administration Impairs Spatial Learning and Memory in Rats Through Brain Mitochondrial Dysfunction, Toxicology and Applied Pharmacology (2023)
16. Evaluation of Acute and Sub-Chronic Oral Toxicities of Neoneaster in Rats, Journal of Ethnopharmacology (2023)
17. Joint Fao/Who Expert Meetings (Jecfa and Jmpr), Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 (2023)
18. Role of Berberis Ssp and Acetaminophen-Induced Acute Liver Injury, Pharmaceutical Chemistry Journal (2023)
19. Green Synthesis, Characterization, and Biological Evaluation of Hydroxyl-Capped Tellurium Nanoparticles, Journal of Sciences# Islamic Republic of Iran (2022)
20. Hybrid Ultrasound-Activated Nanoparticles Based on Graphene Quantum Dots for Cancer Treatment, International Journal of Pharmaceutics (2022)
21. Influence of Reducing Agents on in Situ Synthesis of Gold Nanoparticles and Scaffold Conductivity With Emphasis on Neural Differentiation, Biomaterials Advances (2022)
22. Modification of the Alginate Hydrogel With Fibroblast- and Schwann Cell-Derived Extracellular Matrix Potentiates Differentiation of Mesenchymal Stem Cells Toward Neuron-Like Cells, Journal of Applied Polymer Science (2022)
23. Opioidergic and Nitrergic Systems Mediate the Anticonvulsant Effect of Mefloquine and Chloroquine on Seizures Induced by Pentylenetetrazol and Maximal Electroshock in Mice, Acta Neurobiologiae Experimentalis (2022)
24. Processing of Liposome-Encapsulated Natural Herbs Derived From Silybum Marianum Plants for the Treatment of Breast Cancer Cells, Scientia Iranica (2022)
25. The Situation of Small Molecules Targeting Key Proteins in Combatting Sars-Cov-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications, Mini-Reviews in Medicinal Chemistry (2022)
26. A Rechargeable Drug Delivery System Based on Pnipam Hydrogel for the Local Release of Curcumin, Journal of Applied Polymer Science (2021)
27. Bisphenol-A in Biological Samples of Breast Cancer Mastectomy and Mammoplasty Patients and Correlation With Levels Measured in Urine and Tissue, Scientific Reports (2021)
28. Breast Tumor Targeting in Mice Bearing 4T1 Tumor With Labeled Cxcr4 Antagonist Analogue, International Journal of Peptide Research and Therapeutics (2021)
29. The Ameliorative Effect of Monomethyl Fumarate and Silymarin Against Valproic Acid Induced Hepatotoxicity in Rats, Pharmaceutical Chemistry Journal (2021)
30. Β -Sitosterol Alters the Inflammatory Response in Clp Rat Model of Sepsis by Modulation of Nf Κ B Signaling, BioMed Research International (2021)
31. 177Lu-Labeled Cyclic Rgd Peptide As an Imaging and Targeted Radionuclide Therapeutic Agent in Non-Small Cell Lung Cancer: Biological Evaluation and Preclinical Study, Bioorganic Chemistry (2020)
32. Cytotoxic Activity and Dna Binding Property of New Aminopyrimidine Derivatives, Letters in Drug Design and Discovery (2020)
33. Design, Preparation and Biological Evaluation of a 177Lu-Labeled Somatostatin Receptor Antagonist for Targeted Therapy of Neuroendocrine Tumors, Bioorganic Chemistry (2020)
34. Design, Synthesis, Radiolabeling and Biological Evaluation of New Urea-Based Peptides Targeting Prostate Specific Membrane Antigen, Bioorganic Chemistry (2020)
35. Ficus Carica L. Latex: Possible Chemo-Preventive, Apoptotic Activity and Safety Assessment, Iranian Journal of Pharmaceutical Research (2020)
36. Preclinical Study of a New 177Lu-Labeled Somatostatin Receptor Antagonist in Ht-29 Human Colorectal Cancer Cells, Asia Oceania Journal of Nuclear Medicine and Biology (2020)
37. Radiosynthesis, Biological Evaluation, and Preclinical Study of a 68Ga-Labeled Cyclic Rgd Peptide As an Early Diagnostic Agent for Overexpressed Α V Β 3 Integrin Receptors in Non-Small-Cell Lung Cancer, Contrast Media and Molecular Imaging (2020)
38. Synthesis and Characterization of Novel 99Mtc-Dgc Nano-Complexes for Improvement of Heart Diagnostic, Bioorganic Chemistry (2020)
39. Synthesis, Biological Evaluation and Preclinical Study of a Novel 99Mtc-Peptide: A Targeting Probe of Amyloid-Β Plaques As a Possible Diagnostic Agent for Alzheimer's Disease, Bioorganic Chemistry (2020)
40. Synthesis, Radiolabelling, and Biological Assessment of Folic Acid-Conjugated G-3 99Mtcdendrimer As the Breast Cancer Molecular Imaging Agent, IET Nanobiotechnology (2020)
41. Biofunctionalized Peptide-Based Hydrogel As an Injectable Scaffold for Bdnf Delivery Can Improve Regeneration After Spinal Cord Injury, Injury (2019)
42. Corrigendum to “Biofunctionalized Peptide-Based Hydrogel As an Injectable Scaffold for Bdnf Delivery Can Improve Regeneration After Spinal Cord Injury” [Injury Int. J. Care Injured 50 (2019) 278–285](S0020138318307617)(10.1016/J.Injury.2018.12.027), Injury (2019)
43. Design, Synthesis, Radiolabeling, and Biologic Evaluation of Three 18F-Fdg-Radiolabeled Targeting Peptides for the Imaging of Apoptosis, Cancer Biotherapy and Radiopharmaceuticals (2019)
44. Ellagic Acid Reduces Methotrexate-Induced Apoptosis and Mitochondrial Dysfunction Via Up-Regulating Nrf2 Expression and Inhibiting the Iĸbα/Nfĸb in Rats, DARU# Journal of Pharmaceutical Sciences (2019)
45. Impact of Gold Nanoparticles on Amyloid Β-Induced Alzheimer's Disease in a Rat Animal Model: Involvement of Stim Proteins, ACS Chemical Neuroscience (2019)
46. 99Mtc Labeled Hynic-Edda/Tricine-Ge11 Peptide As a Successful Tumor Targeting Agent, Medicinal Chemistry Research (2018)
47. Acetyl-L-Carnitine Attenuates Arsenic-Induced Liver Injury by Abrogation of Mitochondrial Dysfunction, Inflammation, and Apoptosis in Rats, Environmental Toxicology and Pharmacology (2018)
48. Acetyl-L-Carnitine Attenuates Arsenic-Induced Oxidative Stress and Hippocampal Mitochondrial Dysfunction, Biological Trace Element Research (2018)
49. Development of a 99Mtc-Labeled Cxcr4 Antagonist Derivative As a New Tumor Radiotracer, Cancer Biotherapy and Radiopharmaceuticals (2018)
50. Ethanol Extract of Crataegus Oxyacantha Lameliorate Dietary Non-Alcoholic Fatty Liver Disease in Rat, Drug Research (2018)
51. Monomethyl Fumarate Alleviates Sepsis-Induced Hepatic Dysfunction by Regulating Tlr-4/Nf-Κb Signalling Pathway, Life Sciences (2018)
52. Novel and Efficient Method for Solid Phase Synthesis of Urea-Containing Peptides Targeting Prostate Specific Membrane Antigen (Psma) in Comparison With Current Methods, Iranian Journal of Pharmaceutical Research (2018)
53. Protective Role of Thymoquinone Against Paraquat-Induced Hepatotoxicity in Mice, Pesticide Biochemistry and Physiology (2018)
54. Technetium-99M Chelator-Free Radiolabeling of Specific Glutamine Tumor Imaging Nanoprobe: In Vitro and in Vivo Evaluations, International Journal of Nanomedicine (2018)
55. Technetium-99M Chelator-Free Radiolabeling of Specific Glutamine Tumor Imaging Nanoprobe: In Vitro and in Vivo Evaluations, International Journal of Nanomedicine (2018)
56. 99Mtc-Radiolabeled Ge11-Modified Peptide for Ovarian Tumor Targeting, DARU# Journal of Pharmaceutical Sciences (2017)
57. New Tacrine-Derived Ache/Buche Inhibitors: Synthesis and Biological Evaluation of 5-Amino-2-Phenyl-4H-Pyrano[2,3-B]Quinoline-3-Carboxylates, European Journal of Medicinal Chemistry (2017)
58. Potentiating Role of Copper on Spatial Memory Deficit Induced by Beta Amyloid and Evaluation of Mitochondrial Function Markers in the Hippocampus of Rats, Metallomics (2017)
59. Synthesis and Evaluation of a 99Mtc-Labeled Chemokine Receptor Antagonist Peptide for Imaging of Chemokine Receptor Expressing Tumors, Nuclear Medicine and Biology (2017)
60. 18Fdg-Labeled Likkpf: A Pet Tracer for Apoptosis Imaging, Journal of Radioanalytical and Nuclear Chemistry (2016)
61. Effect of Acetyl-L-Carnitine on Antioxidant Status, Lipid Peroxidation, and Oxidative Damage of Arsenic in Rat, Biological Trace Element Research (2016)
62. Effects of Phloretin on Oxidative and Inflammatory Reaction in Rat Model of Cecal Ligation and Puncture Induced Sepsis, DARU# Journal of Pharmaceutical Sciences (2016)
63. Hynic a Bifunctional Prosthetic Group for the Labelling of Peptides With 99Mtc and 18Fdg, Journal of Radioanalytical and Nuclear Chemistry (2016)
64. Investigation of Securigera Securidaca Seeds Extract and Different Fractions on Serum Glucose, Blood Factors and Liver Morphology in Diabetic Animals, Iranian Journal of Endocrinology and Metabolism (2016)
65. Synthesis, Radiolabeling, and Biological Evaluation of Peptide Likkpf Functionalized With Hynic As Apoptosis Imaging Agent, Iranian Journal of Pharmaceutical Research (2016)
66. Comparative Study of in Vitro Prooxidative Properties and Genotoxicity Induced by Aflatoxin B1 and Its Laccase-Mediated Detoxification Products, Chemosphere (2015)
67. Effects of Teratogenic Drugs on Cyp1a1 Activity in Differentiating Rat Embryo Cells, Drug Research (2015)