Isfahan University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Physicochemical, Pharmaceutical and Biological Approaches Toward Designing Optimized and Efficient Hydrophobically Modified Chitosan-Based Polymeric Micelles As a Nanocarrier System for Targeted Delivery of Anticancer Drugs
Mahboubeh Rezazadeh
Mahboubeh Rezazadeh

Associate Professor of Pharmaceutics

Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences

Novel Drug Delivery Systems Research Center

Isfahan University of Medical Sciences

All Documents
1. Dcs Pulsed With Hypochlorous Acid-Treated Tumor Cell Lysates Present Antigens Efficiently and Induce Cd8 + T Cell Activation Through Cross-Presentation, Research in Pharmaceutical Sciences (2025)
2. Synthesis and in Vitro Evaluation of Novel Ph-Triggered Biocompatible Folate-Chondroitin Sulfate-Dexamethasone Copolymers for Delivery of Tofacitinib in Rheumatoid Arthritis, Research in Pharmaceutical Sciences (2025)
3. The Effect of Bromelain-Acetaminophen Combination on the Intensity of Endodontic Postoperative Pain: A Randomized Clinical Trial, Dental Research Journal (2025)
4. The Role of Gelatin and Collagen in Cell Viability and Osteogenic Potential of an Injectable Chitosan-Based Scaffold Containing Ll37 Peptide, Research in Pharmaceutical Sciences (2025)
5. Preparation and Characterization of Trimethyl Chitosan /Hyaluronic Acid Composite Encapsulated With Ll37 to Promote Wound Healing in an Animal Model, International Journal of Peptide Research and Therapeutics (2023)
6. An Injectable Thermosensitive Hydrogel/Nanomicelles Composite for Local Chemo-Immunotherapy in Mouse Model of Melanoma, Journal of Biomaterials Applications (2022)
7. Preparation and in Vitro Characterization of Histidine Trimethyl Chitosan Conjugated Nanocomplex Incorporated Into Injectable Thermosensitive Hydrogels for Localized Gene Delivery, Biotechnology and Applied Biochemistry (2022)
8. Preparation, Physicochemical, and Retinal Anti-Angiogenic Evaluation of Poloxamer Hydrogel Containing Dexamethasone/Avastin-Loaded Chitosan-N-Acetyl-L-Cysteine Nanoparticles, International Journal of Biological Macromolecules (2022)
9. Pulmonary Delivery of Docetaxel and Celecoxib by Plga Porous Microparticles for Their Synergistic Effects Against Lung Cancer, Anti-Cancer Agents in Medicinal Chemistry (2022)
10. Preparation and Characterization of Eudragit L 100-55/Chitosan Enteric Nanoparticles Containing Omeprazole Using General Factorial Design: In Vitro/In Vivo Study, Research in Pharmaceutical Sciences (2021)
11. Sustained-Release of Erythropoietin Using a Novel Injectable Thermosensitive Hydrogel: In Vitro Studies, Biological Activity, and Efficacy in Rats, Pharmaceutical Development and Technology (2021)
12. The Efficacy of Oral Hydrogel Containing Hyaluronic Acid, Polyvinylpyrrolidone, and Glycyrrhizin for Prevention and Treatment of Oral Mucositis Induced by Chemotherapy, Journal of Isfahan Medical School (2021)
13. Comparison the Effects of Chitosan and Hyaluronic Acid-Based Thermally Sensitive Hydrogels Containing Rosuvastatin on Human Osteoblast-Like Mg-63 Cells, Research in Pharmaceutical Sciences (2020)
14. Simultaneous Determination of Docetaxel and Celecoxib in Porous Microparticles and Rat Plasma by Liquid-Liquid Extraction and Hplc With Uv Detection: In Vitro and in Vivo Validation and Application, Journal of Pharmacy and Pharmaceutical Sciences (2020)
15. Incorporation of Rosuvastatin-Loaded Chitosan/Chondroitin Sulfate Nanoparticles Into a Thermosensitive Hydrogel for Bone Tissue Engineering: Preparation, Characterization, and Cellular Behavior, Pharmaceutical Development and Technology (2019)
16. A Mucoadhesive Thermosensitive Hydrogel Containing Erythropoietin As a Potential Treatment in Oral Mucositis: In Vitro and in Vivo Studies, Drug Delivery and Translational Research (2018)
17. A Novel Mixed Polymeric Micelle for Co-Delivery of Paclitaxel and Retinoic Acid and Overcoming Multidrug Resistance: Synthesis, Characterization, Cytotoxicity, and Pharmacokinetic Evaluation, Drug Development and Industrial Pharmacy (2018)
18. Development and Evaluation of Orally Disintegrating Tablets of Pramipexole Using Full Factorial Design, Iranian Journal of Pharmaceutical Sciences (2018)
19. Effect of Freeze Drying on Stability, Thermo-Responsive Characteristics, and in Vivo Wound Healing of Erythropoietin-Loaded Trimethyl Chitosan/Glycerophosphate Hydrogel, Research in Pharmaceutical Sciences (2018)
20. Preparation and Characterization of an Injectable Thermosensitive Hydrogel for Simultaneous Delivery of Paclitaxel and Doxorubicin, Research in Pharmaceutical Sciences (2018)
21. Preparation and Characterization of Spray-Dried Inhalable Powders Containing Polymeric Micelles for Pulmonary Delivery of Paclitaxel in Lung Cancer, Journal of Pharmacy and Pharmaceutical Sciences (2018)
22. Development and Optimization of Transferrin-Conjugated Nanostructured Lipid Carriers for Brain Delivery of Paclitaxel Using Box–Behnken Design, Pharmaceutical Development and Technology (2017)
23. Targeted Nanostructured Lipid Carriers for Delivery of Paclitaxel to Cancer Cells: Preparation, Characterization, and Cell Toxicity, Current Drug Delivery (2017)
24. A Simple and Sensitive Hplc Method for Analysis of Imipramine in Human Plasma With Uv Detection and Liquid-Liquid Extraction: Application in Bioequivalence Studies, Research in Pharmaceutical Sciences (2016)
25. In Vivo Pharmacokinetics, Biodistribution and Anti-Tumor Effect of Paclitaxel-Loaded Targeted Chitosan-Based Polymeric Micelle, Drug Delivery (2016)
26. A Rapid and Sensitive Hplc Method for Quantitation of Paclitaxel in Biological Samples Using Liquid-Liquid Extraction and Uv Detection: Application to Pharmacokinetics and Tissues Distribution Study of Paclitaxel Loaded Targeted Polymeric Micelles in Tumor Bearing Mice, Journal of Pharmacy and Pharmaceutical Sciences (2015)
27. Co-Delivery of Paclitaxel and Α-Tocopherol Succinate by Novel Chitosan-Based Polymeric Micelles for Improving Micellar Stability and Efficacious Combination Therapy, Drug Development and Industrial Pharmacy (2015)
28. Development and in Vitro/In Vivo Evaluation of a Novel Targeted Polymeric Micelle for Delivery of Paclitaxel, International Journal of Biological Macromolecules (2015)
29. Quantification of Pantoprazole by High Performance Liquid Chromatography (Hplc) Method: In Vitro and in Vivo Applications, Journal of Liquid Chromatography and Related Technologies (2014)
30. Rapid, Sensitive, and Validated Hplc Method for Analysis of Metronidazole and Tinidazole Under Identical Chromatographic Conditions With Uv Detection and Liquid-Liquid Extraction: Application in Bioequivalence Studies, Acta Chromatographica (2013)
31. Formulation of Ldl Targeted Nanostructured Lipid Carriers Loaded With Paclitaxel: A Detailed Study of Preparation, Freeze Drying Condition, and in Vitro Cytotoxicity, Journal of Nanomaterials (2012)
32. Development of a Prolonged-Release Gastroretentive Tablet Formulation of Ciprofloxacin Hydrochloride: Pharmacokinetic Characterization in Healthy Human Volunteers, International Journal of Pharmaceutics (2011)