Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Combination Therapy of Sorafenib With Mesenchymal Stem Cells As a Novel Cancer Treatment Regimen in Xenograft Models of Hepatocellular Carcinoma
Mohsen Nikbakht
Mohsen Nikbakht

Associate Professor of Medical Biotechnology

Shariati Hospital

Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center

Tehran University of Medical Sciences

All Documents
1. Cell Therapy With Placenta-Derived Mesenchymal Stem Cells for Secondary Progressive Multiple Sclerosis Patients in a Phase 1 Clinical Trial, Scientific Reports (2025)
2. Comparative Effects of Arsenic Trioxide and Chemotherapy on Chk1 and Cdc25 Gene Expression in Gastric Cancer Cells Ags and Mkn45: A Potential Therapeutic Strategy, Molecular Biology Reports (2025)
3. Non-Coding Rnas: Emerging Contributors to Chemoresistance in Chronic Myeloid Leukemia, Leukemia Research Reports (2025)
4. Synergistic Enhancement of Apo2l/Trail and Dr4-Induced Apoptosis by Arsenic Trioxide in Triple-Negative Breast Cancer Cells: A Comparison to Conventional Chemotherapy, Cell Biochemistry and Biophysics (2025)
5. Combining Chemotherapy Agents and Autophagy Modulators for Enhanced Breast Cancer Cell Death, Advanced Pharmaceutical Bulletin (2024)
6. Cytokine-Treated Natural Killer Cells Derived From Cord Blood Haematopoietic Stem Cells Exhibit Potential Cytotoxicity Against Cancer Cells, International Journal of Cancer Management (2024)
7. Dual in Vivo T Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation With Post-Transplant Cyclophosphamide and Anti-Thymocyte Globulin As a Third Salvage Transplant for Leukocyte Adhesion Deficiency With Graft Failure: A Case Report, Frontiers in Immunology (2024)
8. Exploring the Potential of Montmorillonite As an Antiproliferative Nanoagent Against Mda-Mb-231 and Mcf-7 Human Breast Cancer Cells, Cells (2024)
9. Exploring the Potential of Montmorillonite As an Antiproliferative Nanoagent Against Mda-Mb-231 and Mcf-7 Human Breast Cancer Cells, Cells (2024)
10. Good Manufacturing Practices Production of Human Placental Derived Mesenchymal Stem Cells for Therapeutic Applications: Focus on Multiple Sclerosis, Molecular Biology Reports (2024)
11. Graft Failure After Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients With Acute Leukemia: Autologous Reconstitution or Second Transplant?, Stem Cell Research and Therapy (2024)
12. Immune Checkpoints and Ncrnas: Pioneering Immunotherapy Approaches for Hematological Malignancies, Cancer Cell International (2024)
13. Cancer Immunotherapy Via Stem Cell-Derived Nk Cells, Immunotherapy (2023)
14. Anti-Inflammatory Effect of Mesenchymal Stem Cells on Hepatocellular Carcinoma in the Xenograft Mice Model, Veterinary Medicine and Science (2022)
15. Development and Characteristics of Layered Egcg/Montmorillonite Hybrid: An Oral Controlled-Release Formulation of Egcg, Journal of Drug Delivery Science and Technology (2022)
16. Long Non-Coding Rna Nr2f2-As1: Its Expanding Oncogenic Roles in Tumor Progression, Human Cell (2022)
17. The Question of Survival or Death: What Is the Role of Autophagy in Acute Myeloid Leukemia (Aml)?, International Journal of Hematology-Oncology and Stem Cell Research (2022)
18. A Focus on Allogeneic Mesenchymal Stromal Cells As a Versatile Therapeutic Tool for Treating Multiple Sclerosis, Stem Cell Research and Therapy (2021)
19. Co-Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells With Hematopoietic Stem Cells Does Not Improve Transplantation Outcome in Class Iii Beta-Thalassemia Major: A Prospective Cohort Study With Long-Term Follow-Up, Pediatric Transplantation (2021)
20. Effects of Different Autophagy Inhibitors on Sensitizing Kg-1 and Hl-60 Leukemia Cells to Chemotherapy, IUBMB Life (2021)
21. Synthesis, Characterization, and in Vitro Evaluation of the Starch-Based Α-Amylase Responsive Hydrogels, Journal of Cellular Physiology (2021)
22. The Effect of Bone Marrow-Derived Mesenchymal Stem Cell Co-Transplantation With Hematopoietic Stem Cells on Liver Fibrosis Alleviation and Survival in Patients With Class Iii Β-Thalassemia Major, Stem Cell Research and Therapy (2021)
23. The Prognostic Impact of Wt1 Expression Levels, Mutations, and Snp Rs16754 in Aml Patients: A Retrospective Cohort Study, Journal of Advances in Medical and Biomedical Research (2021)
24. A Single Center Study of Prescribing and Treatment Outcomes of Patients With Chronic Myeloid Leukemia, International Journal of Hematology-Oncology and Stem Cell Research (2020)
25. Curcumin Combined With Thalidomide Reduces Expression of Stat3 and Bcl-Xl, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines, Drug Design# Development and Therapy (2020)
26. Effects of Mobilized Peripheral Blood Stem Cells on Treatment of Primary Lower Extremity Lymphedema, Journal of Vascular Surgery: Venous and Lymphatic Disorders (2020)
27. Effects of Sorafenib and Arsenic Trioxide on U937 and Kg-1 Cell Lines: Apoptosis or Autophagy?, Cell Journal (2020)
28. Evaluation of Molecular Response to Imatinib Mesylate Treatment in Iranian Patients With Chronic Myeloid Leukemia, Clinical Lymphoma# Myeloma and Leukemia (2020)
29. Indirect Tumor Inhibitory Effects of Microrna-124 Through Targeting Ezh2 in the Multiple Myeloma Cell Line, Cell Journal (2020)
30. Montmorillonite, a Natural Biocompatible Nanosheet With Intrinsic Antitumor Activity, Colloids and Surfaces B: Biointerfaces (2020)
31. Osteopontin Sirna Does Not Confer Resistance to Toxic Effects of Parthenolide in Jurkat Cells, Experimental Oncology (2020)
32. Sorafenib and Mesenchymal Stem Cell Therapy: A Promising Approach for Treatment of Hcc, Evidence-based Complementary and Alternative Medicine (2020)
33. A Randomized Controlled Trial of Effectiveness of Platelet-Rich Plasma Gel and Regular Dressing on Wound Healing Time in Pilonidal Sinus Surgery: Role of Different Affecting Factors, Biomedical Journal (2019)
34. Arsenic Trioxide and Thalidomide Combination Induces Autophagy Along With Apoptosis in Acute Myeloid Cell Lines, Cell Journal (2019)
35. Combination Therapy of Sorafenib With Mesenchymal Stem Cells As a Novel Cancer Treatment Regimen in Xenograft Models of Hepatocellular Carcinoma, Journal of Cellular Physiology (2019)
36. Comparison of Delta- Pcr and Conventional Fragment Analysis for the Detection of Flt3-Itd Mutations in Paired Diagnosis-Relapse Samples of Patients With Acute Myeloid Leukemia, Journal of Advances in Medical and Biomedical Research (2019)
37. Microvesicles of Osteoblasts Modulate Bone Marrow Mesenchymal Stem Cell-Induced Apoptosis to Curcumin in Myeloid Leukemia Cells, Journal of Cellular Physiology (2019)
38. Peripheral Blood Stem Cell Apheresis in Low-Weight Children: A Single Centre Study, Transfusion and Apheresis Science (2019)
39. Study of Stat3 Expression in Different Phases of Patients With Chronic Myeloid Leukemia, Journal of Payavard Salamat (2019)
40. Evaluation of the Gene Expression of the Cytoprotective Proteins in Response to Daunorubicin in U937 Cells, International Journal of Cancer Management (2018)
41. Flt3-Itd Compared With Dnmt3a R882 Mutation Is a More Powerful Independent Inferior Prognostic Factor in Adult Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study; [Allojenik Hematopoetik Kok Hucre Nakli Sonrasi Yetiskin Akut Myeloid Losemi Hastalarinda, Flt3-Itd, Dnmt3a R882 Mutasyonu Ile Karsilastirildiginda Daha Guclu Bir Bagimsiz Kotu Prognostik Faktordur: Retrospektif Kohort Calismasi], Turkish Journal of Hematology (2018)
42. Inhibitory Effects of Arsenic Trioxide and Thalidomide on Angiogenesis and Vascular Endothelial Growth Factor Expression in Leukemia Cells, Asian Pacific Journal of Cancer Prevention (2018)
43. Minimal Residual Disease (Mrd) Detection Using Rearrangement of Immunoglobulin/T Cell Receptor Genes in Adult Patients With Acute Lymphoblastic Leukemia (All), Annals of Hematology (2018)
44. Photopheresis of a Less Than 10-Kg Child With Acute Graft Versus Host Disease Accompanied With Hyperbilirubinemia: A Case Report, Transfusion and Apheresis Science (2018)
45. The Role of Donor Leukocyte Infusions in the Treatment of Relapsed Acute Leukemia After Allogeneic Stem Cell Transplantation: A Retrospective Analysis, International Journal of Hematology-Oncology and Stem Cell Research (2018)
46. Aberrant Promoter Hypermethylation of Selected Apoptotic Genes in Childhood Acute Lymphoblastic Leukemia Among North Indian Population, Experimental Oncology (2017)
47. An Alternative Method for Custom Prime: A Case Report of Successful Peripheral Blood Stem Cell Harvesting From Two Low-Weight Child Donors, Transfusion and Apheresis Science (2017)
48. Anti-Apoptotic Effects of Osteopontin Via the Up-Regulation of Akt/Mtor/Β-Catenin Loop in Acute Myeloid Leukemia Cells, International Journal of Hematology-Oncology and Stem Cell Research (2017)
49. Anti-Vascular Endothelial Growth Factor Effects of Sorafenib and Arsenic Trioxide in Acute Myeloid Leukemia Cell Lines, Asian Pacific Journal of Cancer Prevention (2017)
50. Anti-Vascular Endothelial Growth Factor Targeting by Curcumin and Thalidomide in Acute Myeloid Leukemia Cells, Asian Pacific Journal of Cancer Prevention (2017)
51. Evaluation of Platelet-Rich Plasma Gel Potential in Acceleration of Wound Healing Duration in Patients Underwent Pilonidal Sinus Surgery: A Randomized Controlled Parallel Clinical Trial, Transfusion and Apheresis Science (2017)
52. Evaluation of Wound Healing in Diabetic Foot Ulcer Using Platelet-Rich Plasma Gel: A Single-Arm Clinical Trial, Transfusion and Apheresis Science (2017)
53. Opn B and C Isoforms Doubtless Veto Anti-Angiogenesis Effects of Curcumin in Combination With Conventional Aml Regiment, Asian Pacific Journal of Cancer Prevention (2017)
54. Optimizing Peripheral Blood Stem Cells Transplantation Outcome Through Amend Relapse and Graft Failure: A Review of Current Literature, Experimental Hematology and Oncology (2017)
55. Optimizing Stem Cells Mobilization Strategies to Ameliorate Patient Outcomes: A Review of Guide Lines and Recommendations, International Journal of Hematology-Oncology and Stem Cell Research (2017)
56. Osteopontin B and C Isoforms: Molecular Candidates Associated With Leukemic Stem Cell Chemoresistance in Acute Myeloid Leukemia, Asian Pacific Journal of Cancer Prevention (2017)
57. Osteopontin Plays a Unique Role in Resistance of Cd34 +/Cd123 + Human Leukemia Cell Lines Kg1a to Parthenolide, Life Sciences (2017)
58. Parthenolide Reduces Gene Transcription of Prosurvival Mediators in U937 Cells, Experimental Oncology (2017)
59. Reciprocal Interactions of Leukemic Cells With Bone Marrow Stromal Cells Promote Enrichment of Leukemic Stell Cell Compartments in Response to Curcumin and Daunorubicin, Asian Pacific Journal of Cancer Prevention (2017)
60. Stem Cell Therapy for Intervertebral Disc Regeneration: Review Article, Tehran University Medical Journal (2017)
61. Acquired Expression of Osteopontin Selectively Promotes Enrichment of Leukemia Stem Cells Through Akt/Mtor/Pten/Β-Catenin Pathways in Aml Cells, Life Sciences (2016)
62. Curcumin Veto the Effects of Osteopontin (Opn) Specific Inhibitor on Leukemic Stem Cell Colony Forming Potential Via Promotion of Opn Overexpression, International Journal of Hematology-Oncology and Stem Cell Research (2016)
63. Erratum To: A Comparative Analysis of Methylation Status of Tumor Suppressor Genes in Paired Biopsy and Serum Samples From Cervical Cancer Patients Among North Indian Population (Russian Journal of Genetics, (2016), 52, (226), 10.1134/S1022795416010075), Russian Journal of Genetics (2016)
64. Human Platelet Lysate As a Xeno Free Alternative of Fetal Bovine Serum for the in Vitro Expansion of Human Mesenchymal Stromal Cells, International Journal of Hematology-Oncology and Stem Cell Research (2016)
65. Expression of Collagen Type I and Ii, Aggrecan and Sox9 Genes in Mesenchymal Stem Cells on Different Bioscaffolds, Tehran University Medical Journal (2015)