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Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Evaluation of Apamin Effects on Myelination Process in C57bl/6 Mice Model of Multiple Sclerosis

Mehdi Aliomrani

Mehdi Aliomrani

Associate Professor of Pharmacology and Toxicology

Department of Pharmacology and Toxicology, School of Pharmacy and Pharmaceutical Sciences

Isfahan University of Medical Sciences

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1. Evaluation of Apamin Effects on Myelination Process in C57bl/6 Mice Model of Multiple Sclerosis, Research in Pharmaceutical Sciences (2019)

2. Bee Venom–Derived Bbb Shuttle and Its Correlation With Oligodendrocyte Proliferation Markers in Mice Model of Multiple Sclerosis, Neurotoxicity Research (2021)

3. Analysis of Platelet-Derived Growth Factor Receptor a and Oligodendrocyte Transcription Factor 2 Markers Following Hydroxychloroquine Administration in Animal Induced Multiple Sclerosis Model, Metabolic Brain Disease (2021)

4. Apamin As a Bbb Shuttle and Its Effects on T Cell Population During the Experimental Autoimmune Encephalomyelitis-Induced Model of Multiple Sclerosis, Neurotoxicity Research (2021)

5. Apamin Administration Impact on Mir-219 and Mir-155-3P Expression in Cuprizone Induced Multiple Sclerosis Model, Molecular Biology Reports (2020)

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1. Enhancing Adhesive Performance With N, N, N', N'-Tetrakis (2-Pyridyl Methyl) Ethylenediamine Matrix Metalloproteinase Inhibitors: A Comprehensive Study of Degree of Conversion, Microleakage, and Micro-Tensile Bond Strength in Dental Adhesives, Journal of Conservative Dentistry and Endodontics (2025)

2. Bupropion and Varenicline Administration Reversed Depressive Behavior Induced by Acetamiprid Exposure in Mice: The Role of Nachrs in Depression, Toxicology Research (2024)

3. Design, Synthesis, Bioactivity Analyses, and Molecular Docking Study of Triazine-Tyrosine Based Derivatives As Drugs Like Fingolimod for Treatment of Multiple Sclerosis, Polycyclic Aromatic Compounds (2024)

4. Extraction, Purification and Characterization of Immunomodulatory Effects of Cyclotides Isolated From Viola Odorata; [استخراج، جداسازی و تعیین اثرات تنظیم کنندگی سیستم ایمنی پپتیدهای حلقویviola Odorata مستخرج], Journal of Isfahan Medical School (2024)

5. Hybrid Derivatives Containing Dimethyl Fumarate and Benzothiazole Scaffolds for the Potential Treatment of Multiple Sclerosis; in Silico & in Vivo Study, DARU, Journal of Pharmaceutical Sciences (2024)

6. Investigating the Effect of Cgrp78 Vaccine Against Different Cancer Cells and Its Role in Reducing Melanoma Metastasis, Research in Pharmaceutical Sciences (2024)

7. Investigating the Effect of Cgrp78 Vaccine Against Different Cancer Cells and Its Role in Reducing Melanoma Metastasis, Research in Pharmaceutical Sciences (2024)

8. Polydopamine Coated Surfactin Micelles for Brain Delivery of Ibudilast in Multiple Sclerosis: Design, Optimization, in Vitro and in Vivo Evaluation, Journal of Drug Delivery Science and Technology (2024)

9. Aqueous Self-Assembly of Extracted Cyclotides From Viola Odorata Into Novel Stable Supramolecular Structures, Journal of Molecular Liquids (2023)

10. Correction To: Perfluorooctanoic Acid Exposure and Its Neurodegenerative Consequences in C57bl6/J Mice (Naunyn-Schmiedeberg's Archives of Pharmacology, (2023), 396, 10, (2357-2367), 10.1007/S00210-023-02387-8), Naunyn-Schmiedeberg's Archives of Pharmacology (2023)

11. Cyclotide Nanotubes As a Novel Potential Drug-Delivery System: Characterization and Biocompatibility, International Journal of Pharmaceutics (2023)

12. Effect of Pretreatment With a Synbiotic on Perfluorooctanoic Acid-Induced Liver Damage After Sub-Acute Oral Exposure in C57bl/6J Mice, Toxicology and Applied Pharmacology (2023)

13. Introduction of a New Recombinant Vaccine Based on Grp78 for Breast Cancer Immunotherapy and Evaluation in a Mouse Model, BioImpacts (2023)

14. Introduction of a New Recombinant Vaccine Based on Grp78 for Breast Cancer Immunotherapy and Evaluation in a Mouse Model, BioImpacts (2023)

15. Nose to Brain Delivery of Ibudilast Micelles for Treatment of Multiple Sclerosis in an Experimental Autoimmune Encephalomyelitis Animal Model, International Journal of Pharmaceutics (2023)

16. Perfluorooctanoic Acid Exposure and Its Neurodegenerative Consequences in C57bl6/J Mice, Naunyn-Schmiedeberg's Archives of Pharmacology (2023)

17. Copper-Curcumin-Bipyridine Dicarboxylate Complexes As Anticancer Candidates, Chemistry and Biodiversity (2022)

18. Creatine and Alpha-Lipoic Acid Antidepressant-Like Effect Following Cyclosporine a Administration, Turkish Journal of Pharmaceutical Sciences (2022)

19. Design and Synthesis of Some Novel Triazine-Tyrosine Hybrids As Potential Agents for the Treatment of Multiple Sclerosis, Research in Pharmaceutical Sciences (2022)

20. Effects of Asparagus Officinalis on Immune System Mediated Eae Model of Multiple Sclerosis, Toxicology Research (2022)

21. Glutathione Targeted Tragacanthic Acid-Chitosan As a Non-Viral Vector for Brain Delivery of Mirna-219A-5P: An in Vitro/In Vivo Study, International Journal of Biological Macromolecules (2022)

22. Hyaluronic Acid Targeted Metal Organic Framework Based on Iron (Iii) for Delivery of Platinum Curcumin Cytotoxic Agent to Triple Negative Breast Cancer Cell Line, Applied Organometallic Chemistry (2022)

23. Immunomodulatory Effects of Cyclotides Isolated From Viola Odorata in an Experimental Autoimmune Encephalomyelitis Animal Model of Multiple Sclerosis, Multiple Sclerosis and Related Disorders (2022)

24. Morphological Studies of Self-Assembled Cyclotides Extracted From Viola Odorata As Novel Versatile Platforms in Biomedical Applications, Biomaterials Science (2022)

25. Research Paper Involvement of Mice Hippocampus Brain-Derived Neurotrophic Factor in Diazinon-Induced Depressive Behavior in Mice, Iranian Journal of Toxicology (2022)

26. 4-Hydroxyhalcone Effects on Cisplatin-Induced Genotoxicity Model, Toxicology Research (2021)

27. Achr Is Partly Responsible in Mice Depressive-Like Behavior After Phosalone Exposure, Neurotoxicology and Teratology (2021)

28. Analysis of Platelet-Derived Growth Factor Receptor a and Oligodendrocyte Transcription Factor 2 Markers Following Hydroxychloroquine Administration in Animal Induced Multiple Sclerosis Model, Metabolic Brain Disease (2021)

29. Antioxidant Effects of Pinus Eldarica Extracts Against Cisplatin-Induced Cytotoxicity in Human Hepatoma (Hepg2) Cell Line, Iranian Journal of Toxicology (2021)

30. Apamin As a Bbb Shuttle and Its Effects on T Cell Population During the Experimental Autoimmune Encephalomyelitis-Induced Model of Multiple Sclerosis, Neurotoxicity Research (2021)

31. Bee Venom–Derived Bbb Shuttle and Its Correlation With Oligodendrocyte Proliferation Markers in Mice Model of Multiple Sclerosis, Neurotoxicity Research (2021)

32. Changes in Dna Methylation in Apoe and Ackr3 Genes in Multiple Sclerosis Patients and the Relationship With Their Heavy Metal Blood Levels, NeuroToxicology (2021)

33. Changes in Dna Methylation in Apoe and Ackr3 Genes in Multiple Sclerosis Patients and the Relationship With Their Heavy Metal Blood Levels, NeuroToxicology (2021)

34. Investigating the Effects of Bark Extract and Volatile Oil of Pinus Eldarica Against Cisplatin-Induced Genotoxicity on Huvecs Cell Line, Toxicology Research (2021)

35. Risk of Neurodegenerative Disease Due to Tau Phosphorylation Changes and Arsenic Exposure Via Drinking Water, Toxicology Research (2021)

36. Risk of Neurodegenerative Disease Due to Tau Phosphorylation Changes and Arsenic Exposure Via Drinking Water, Toxicology Research (2021)

37. Study of the Probable Genotoxic Effects of Zolone (Phosalone) Exposure in Mice Bone Marrow Derived Cells, Genes and Environment (2021)

38. The Probable Genotoxic Effects of Phosalone Exposure in Mice Bone Marrow Cells, Journal of Isfahan Medical School (2021)

39. Apamin Administration Impact on Mir-219 and Mir-155-3P Expression in Cuprizone Induced Multiple Sclerosis Model, Molecular Biology Reports (2020)

40. Hydroxychloroquine Effects on Mir-155-3P and Mir-219 Expression Changes in Animal Model of Multiple Sclerosis, Metabolic Brain Disease (2020)

41. Mechanisms and Pathogenesis Underlying Environmental Chemical-Induced Necroptosis, Environmental Science and Pollution Research (2020)

42. Mechanisms and Pathogenesis Underlying Environmental Chemical-Induced Necroptosis, Environmental Science and Pollution Research (2020)

43. Cadmium Separation in Human Biological Samples Based on Captopril-Ionic Liquid Paste on Graphite Rod Before Determination by Electrothermal Atomic Absorption Spectrometry, Analytical Methods in Environmental Chemistry Journal (2019)

44. Cadmium Separation in Human Biological Samples Based on Captopril-Ionic Liquid Paste on Graphite Rod Before Determination by Electrothermal Atomic Absorption Spectrometry, Analytical Methods in Environmental Chemistry Journal (2019)

45. Chronic Oral Arsenic Exposure and Its Correlation With Serum S100b Concentration, Biological Trace Element Research (2019)

46. Evaluation of Apamin Effects on Myelination Process in C57bl/6 Mice Model of Multiple Sclerosis, Research in Pharmaceutical Sciences (2019)

47. Is There Any Relevance Between Serum Heavy Metal Concentration and Bbb Leakage in Multiple Sclerosis Patients?, Biological Trace Element Research (2019)

48. Lhrh Targeted Chonderosomes of Mitomycin C in Breast Cancer: An in Vitro/ in Vivo Study, Anti-Cancer Agents in Medicinal Chemistry (2019)

49. Synthesis and Antiproliferative Evaluation of Some Iron Chelators As Polyamine Transporter Targeting Agents, Canadian Journal of Chemistry (2019)

50. The Prevalence of the Genetic Polymorphism of Gstm1, Gstt1 and Gstp1 and Its Relationship With Clinical Criteria of Multiple Sclerosis (Ms) Patients in Tehran, Journal of Babol University of Medical Sciences (2019)

51. The Prevalence of the Genetic Polymorphism of Gstm1, Gstt1 and Gstp1 and Its Relationship With Clinical Criteria of Multiple Sclerosis (Ms) Patients in Tehran, Journal of Babol University of Medical Sciences (2019)

52. Correlation Between Heavy Metal Exposure and Gstm1 Polymorphism in Iranian Multiple Sclerosis Patients, Neurological Sciences (2017)

53. Correlation Between Heavy Metal Exposure and Gstm1 Polymorphism in Iranian Multiple Sclerosis Patients, Neurological Sciences (2017)

54. Blood Concentrations of Cadmium and Lead in Multiple Sclerosis Patients From Iran, Iranian Journal of Pharmaceutical Research (2016)

55. Effects of Phloretin on Oxidative and Inflammatory Reaction in Rat Model of Cecal Ligation and Puncture Induced Sepsis, DARU# Journal of Pharmaceutical Sciences (2016)