Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Klotho Induces Insulin Resistance Possibly Through Interference With Glut4 Translocation and Activation of Akt, Gsk3β, and Pfkfβ3 in 3T3-L1 Adipocyte Cells
Nepton Soltani
Nepton Soltani

Professor of Physiology

Department of Physiology, School of Medicine

Isfahan University of Medical Sciences

All Documents
1. Chemical Composition, Molecular Docking Analysis, and Biological Properties of Salvia Mirzayanii, Advanced Biomedical Research (2025)
2. Effects of Salvia Mirzayanii Extract Administration on Hyperglycemia Improvement in Diabetic Rats: The Role of Glut4, Pepck and G6pase Genes, Heliyon (2024)
3. Long Term Administration of Thiamine Disulfide Improves Foxo1/Pepck Pathway in Liver to Reduce Insulin Resistance in Type 1 Diabetes Rat Model, Biomedicine and Pharmacotherapy (2024)
4. Long-Term Gaba Supplementation Regulates Diabetic Gastroenteropathy Through Gaba Receptor/Trypsin-1/Pars/Akt/Cox-2 Axis, Doklady Biochemistry and Biophysics (2024)
5. The Effect of Long-Term Magnesium Treatment on Changes in Hepatic Autophagic and Apoptotic Ability of Type 2 Diabetic Female Rats and Their Offspring, Gene Reports (2024)
6. Changes in Protease-Activated Receptor and Trypsin-1 Expression Are Involved in the Therapeutic Effect of Mg2+Supplementation in Type 2 Diabetes-Induced Gastric Injury in Male Adult Rats, Advances in Pharmacological and Pharmaceutical Sciences (2023)
7. Comparative Study of Anti-Diabetic Effects of Insulin, Epigenin and Salvia Mirzayanii Extract in Streptozotocin-Induced Diabetic Male Rats, Indian Journal of Biochemistry and Biophysics (2023)
8. Gamma-Aminobutyric Acid Attenuates Insulin Resistance in Type 2 Diabetic Patients and Reduces the Risk of Insulin Resistance in Their Offspring, Koomesh (2023)
9. Impact of Magnesium Sulfate Therapy in Improvement of Renal Functions in High Fat Diet-Induced Diabetic Rats and Their Offspring, Scientific Reports (2023)
10. Magnesium Supplementation Affects the Expression of Sirtuin1, Tumor Protein P53 and Endothelial Nitric Oxide Synthase Genes in Patients With Atherosclerosis: A Double-Blind, Randomized, Placebo-Controlled Trial, Indian Journal of Clinical Biochemistry (2023)
11. The Effects of Aerobic Exercise on Liver Function, Insulin Resistance, and Lipid Profiles in Prediabetic and Type 2 Diabetic Mice, Physiology and Behavior (2023)
12. The Potential of Magnesium Sulfate to Change Serum Lysyl Oxidase and Nitrite Levels in Patients With Atherosclerosis: A Double-Blind Clinical Trial Study, Journal of Kerman University of Medical Sciences (2023)
13. Beneficial Effects of Mgso4 on Tfam, Upc3 and Fndc5 Mrna Expressions in Skeletal Muscle of Type 2 Diabetic Rats: A Possible Mechanism to Improve Insulin Resistance, Molecular Biology Reports (2022)
14. Combination Therapy With Gaba and Mgso4improves Insulin Sensitivity in Type 2 Diabetic Rat, International Journal of Endocrinology (2022)
15. Glucose Transporters in Kidney; the Role of Gender and Diabetes Mellitus, Journal of Nephropharmacology (2022)
16. Long-Term Gaba Administration Improves Fndc5, Tfam, and Ucp3 Mrna Expressions in the Skeletal Muscle and Serum Irisin Levels in Chronic Type 2 Diabetic Rats, Naunyn-Schmiedeberg's Archives of Pharmacology (2022)
17. The Role of Pancreas to Improve Hyperglycemia in Stz-Induced Diabetic Rats by Thiamine Disulfide, Nutrition and Diabetes (2022)
18. The Therapeutic Effects of Magnesium in Insulin Secretion and Insulin Resistance, Advanced Biomedical Research (2022)
19. Gaba Administration Improves Liver Function and Insulin Resistance in Offspring of Type 2 Diabetic Rats, Scientific Reports (2021)
20. Gamma-Aminobutyric Acid Attenuates Insulin Resistance in Type 2 Diabetic Patients and Reduces the Risk of Insulin Resistance in Their Offspring, Biomedicine and Pharmacotherapy (2021)
21. Insulin Resistance and the Role of Gamma-Aminobutyric Acid, Journal of Research in Medical Sciences (2021)
22. Magnesium Sulfate Improves Insulin Resistance in High Fat Diet Induced Diabetic Parents and Their Offspring, European Journal of Pharmacology (2021)
23. Magnesium Sulfate Administration in Moderate Coronary Artery Disease Patients Improves Atherosclerotic Risk Factors: A Double-Blind Clinical Trial Study, Journal of Cardiovascular Pharmacology (2020)
24. Magnesium Sulfate Administration in Moderate Coronary Artery Disease Patients Improves Atherosclerotic Risk Factors: A Double-Blind Clinical Trial Study, Journal of Cardiovascular Pharmacology (2020)
25. Magnesium Sulfate Improves Some Risk Factors for Atherosclerosis in Patients Suffering From One or Two Coronary Artery Diseases: A Double-Blind Clinical Trial Study, Clinical Pharmacology: Advances and Applications (2020)
26. Magnesium Sulfate Improves Some Risk Factors for Atherosclerosis in Patients Suffering From One or Two Coronary Artery Diseases: A Double-Blind Clinical Trial Study, Clinical Pharmacology: Advances and Applications (2020)
27. Effect of Long-Term Administration of Oral Magnesium Sulfate and Insulin to Reduce Streptozotocin-Induced Hyperglycemia in Rats: The Role of Akt2 and Irs1 Gene Expressions, Biological Trace Element Research (2019)
28. Effect of Oral Magnesium Sulfate Administration on Blood Glucose Hemostasis Via Inhibition of Gluconeogenesis and Foxo1 Gene Expression in Liver and Muscle in Diabetic Rats, Biomedicine and Pharmacotherapy (2019)
29. Effect of Oral Magnesium Sulfate Administration on Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Gene Expression to Prevent Atherosclerosis in Diabetic Rat Vessels, Journal of Diabetes Investigation (2019)
30. Oral Herbal Supplement Containing Magnesium Sulfate Improve Metabolic Control and Insulin Resistance in Non-Diabetic Overweight Patients: A Randomized Double Blind Clinical Trial, Medical Journal of the Islamic Republic of Iran (2019)
31. Oral Herbal Supplement Containing Magnesium Sulfate Improve Metabolic Control and Insulin Resistance in Non-Diabetic Overweight Patients: A Randomized Double Blind Clinical Trial, Medical Journal of the Islamic Republic of Iran (2019)
32. Effect of Magnesium Sulfate Administration to Improve Insulin Resistance in Type 2 Diabetes Animal Model: Using the Hyperinsulinemic-Euglycemic Clamp Technique, Fundamental and Clinical Pharmacology (2018)
33. Gaba Dramatically Improves Glucose Tolerance in Streptozotocin-Induced Diabetic Rats Fed With High-Fat Diet, European Journal of Pharmacology (2018)
34. Effect of the Administration of Solanum Nigrum Fruit on Prevention of Diabetic Nephropathy in Streptozotocin-Induced Diabetic Rats, Pharmacognosy Research (2017)
35. Nephroprotective Effect of Estrogen and Progesterone Combination on Cisplatin-Induced Nephrotoxicity in Ovariectomized Female Rats, Indian Journal of Nephrology (2016)
36. Role of Gabab Receptor and L-Arg in Gaba-Induced Vasorelaxation in Non-Diabetic and Streptozotocin-Induced Diabetic Rat Vessels, Iranian Biomedical Journal (2015)
37. Effect of Oral Administration of Magnesium on Cisplatin-Induced Nephrotoxicity in Normal and Streptozocin-Induced Diabetic Rats, Nephro-Urology Monthly (2013)
38. Measured Vs. Calculated Plasma Osmolality in Infants and Head Injured Patients in Critical Care Units, Clinical and Experimental Medical Letters (2008)
39. Gender Difference in Endothelial Permeability of Aorta in Rabbits Consuming Normal or High-Cholesterol Diets, Iranian Journal of Medical Sciences (2003)