Metabolomics Signatures of Sars-Cov-2 Infection Publisher Pubmed



Arjmand B^{1, 2} ; Alavimoghadam S¹ ; Parhizkarroudsari P² ; Rezaeitavirani M³ ; Tayanloobeik A¹ ; Goodarzi P⁴ ; Mehrdad N⁵ ; Mohamadijahani F⁴ ; Larijani B⁶
Source: Advances in Experimental Medicine and Biology Published:2022

Abstract

For a very long time, viral infections have been considered as one of the most important causes of death and disability around the world. Through the viral infection, viruses as small pathogens enter the host cells and use hosts’ biosynthesis machinery to replicate and collect infectious lineages. Moreover, they can modify hosts’ metabolic pathways in order to their own purposes. Nowadays (in 2019–2020), the most famous type of viral infection which was caused by a novel type of coronavirus is called COVID-19 disease. It has claimed the lives of many people around the world and is a very serious threat to health. Since investigations of the effects of viruses on host metabolism using metabolomics tools may have given focuses on novel appropriate treatments, in the current review the authors highlighted the virus-host metabolic interactions and metabolomics perspective in COVID-19. © 2021, Springer Nature Switzerland AG.