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Association Between Cardiometabolic Risk Factors and Covid-19 Susceptibility, Severity and Mortality: A Review Publisher



Sharifi Y1, 2 ; Payab M3 ; Mohammadivajari E4 ; Aghili SMM1 ; Sharifi F5 ; Mehrdad N6, 7 ; Kashani E8 ; Shadman Z5 ; Larijani B1 ; Ebrahimpur M5
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Yaas Diabetes and Metabolic Diseases Research Center, Indiana University School of Medicine, Indianapolis, 46202, IN, United States
  3. 3. Metabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Student of Medicine, School of Medicine, Gilan University of Medical Sciences, Rasht, Iran
  5. 5. Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Nursing Care Research Center, Iran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Obstetrics and Gynecology, Golestan University of Medical Sciences, Golestan, Iran

Source: Journal of Diabetes and Metabolic Disorders Published:2021


Abstract

The novel coronavirus, which began spreading from China Wuhan and gradually spreaded to most countries, led to the announcement by the World Health Organization on March 11, 2020, as a new pandemic. The most important point presented by the World Health Organization about this disease is to better understand the risk factors that exacerbate the course of the disease and worsen its prognosis. Due to the high majority of cardio metabolic risk factors like obesity, hypertension, diabetes, and dyslipidemia among the population over 60 years old and higher, these cardio metabolic risk factors along with the age of these people could worsen the prognosis of the coronavirus disease of 2019 (COVID-19) and its mortality. In this study, we aimed to review the articles from the beginning of the pandemic on the impression of cardio metabolic risk factors on COVID-19 and the effectiveness of COVID-19 on how to manage these diseases. All the factors studied in this article, including hypertension, diabetes mellitus, dyslipidemia, and obesity exacerbate the course of Covid-19 disease by different mechanisms, and the inflammatory process caused by coronavirus can also create a vicious cycle in controlling these diseases for patients. © 2021, Springer Nature Switzerland AG.
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