A Review on Molecular Typing Methods for Aspergillus Species



Khodavaisy S^{1, 2} ; Rezaie S³ ; Ahmadi M⁴ ; Hassanpour Z⁵ ; Roshan R⁶ ; Falahatinejad M⁷ ; Davoudi MM⁷ ; Badali H⁸ Show Affiliations
Source: Journal of Mazandaran University of Medical Sciences Published:2015

Abstract

Conidia of Aspergillus species are widely distributed and ubiquitous in outdoor and hospital environments. There are high numbers of patients with weakened immune systems, therefore Aspergillus infections are increasing in hospitals. Molecular typing of Aspergillus strains obtained from patients and their environment is an important tool for epidemiological and public health studies. Fingerprinting for Aspergillus species especially fumigatus and flavus adjusted from respiratory samples and environment requires high quality typing methods. In recent years several molecular typing methods have been established for different Aspergillus species. These methods are more useful than conventional methods and are of great importance due to being more practically accessible, easy to use, having high ability in diagnosis, repeatable and sensitive to change in one laboratory and between different laboratories, and easy interpretation of data. Today accurate typing methods include Multilocus Sequence Typing (MLST) and micro satellites. In ccurrent review different molecular methods for Aspergillus species genotyping are discussed to obtain a better insight into epidemiology of this pathogen. © 2015, Mazandaran University of Medical Sciences. All rights reserved.