Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering

Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering Publisher Pubmed

Barabadi Z¹ ; Azami M¹ ; Sharifi E² ; Karimi R¹ ; Lotfibakhshaiesh N¹ ; Roozafzoon R¹ ; Joghataei MT³ ; Ai J^{1, 4}

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1. Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
2. Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
3. Anatomy Department, Iran University of Medical Sciences, Tehran, Iran
4. Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Materials Science and Engineering C Published:2016

Abstract

Selecting suitable cell sources and angiogenesis induction are two important issues in myocardial tissue engineering. Human endometrial stromal cells (EnSCs) have been introduced as an abundant and easily available resource in regenerative medicine. Bioactive glass is an agent that induces angiogenesis and has been studied in some experiments. The aim of this study was to investigate in vitro differentiation capacity of endometrial stem cells into cardiomyocyte lineage and to evaluate capability of bioactive glass nanoparticles toward EnSCs differentiation into endothelial lineage and angiogenesis on hydrogel scaffold. Our findings suggests that endometrial stem cells could be programmed into cardiomyocyte linage and considered a suitable cell source for myocardial regeneration. This experiment also revealed that inclusion of bioactive glass nanoparticles in hydrogel scaffold could improve angiogenesis through differentiating EnSCs toward endothelial lineage and increasing level of vascular endothelial growth factor secretion. © 2016 Elsevier B.V.

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Somayeh Ebrahimi Barough (7)

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Style	Citing Format
MLA	Barabadi Z, et al.. "Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering." Materials Science and Engineering C, vol. 69, no. , 2016, pp. 1137-1146.
APA	Barabadi Z, Azami M, Sharifi E, Karimi R, Lotfibakhshaiesh N, Roozafzoon R, Joghataei MT, Ai J (2016). Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering. Materials Science and Engineering C, 69(), 1137-1146.
Chicago	Barabadi Z, Azami M, Sharifi E, Karimi R, Lotfibakhshaiesh N, Roozafzoon R, Joghataei MT, Ai J. "Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering." Materials Science and Engineering C 69, no. (2016): 1137-1146.
Harvard	Barabadi Z et al. (2016) 'Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering', Materials Science and Engineering C, 69(), pp. 1137-1146.
Vancouver	Barabadi Z, Azami M, Sharifi E, Karimi R, Lotfibakhshaiesh N, Roozafzoon R, et al.. Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering. Materials Science and Engineering C. 2016;69():1137-1146.
BibTex	@article{ author = {Barabadi Z and Azami M and Sharifi E and Karimi R and Lotfibakhshaiesh N and Roozafzoon R and Joghataei MT and Ai J}, title = {Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering}, journal = {Materials Science and Engineering C}, volume = {69}, number = {}, pages = {1137-1146}, year = {2016} }
RIS	TY - JOUR AU - Barabadi Z AU - Azami M AU - Sharifi E AU - Karimi R AU - Lotfibakhshaiesh N AU - Roozafzoon R AU - Joghataei MT AU - Ai J TI - Fabrication of Hydrogel Based Nanocomposite Scaffold Containing Bioactive Glass Nanoparticles for Myocardial Tissue Engineering JO - Materials Science and Engineering C VL - 69 IS - SP - 1137 EP - 1146 PY - 2016 ER -

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