Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]

Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos] Publisher Pubmed

Miratashi Yazdi SA¹ ; Hoseini F² ; Eftekhar Javadi A² ; Nazar E²

Show Affiliations

1. Department of General Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Pathology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Revista Espanola de Patologia Published:2024

Abstract

Introduction: Phosphatase and tensin homologue (PTEN) is an important tumour suppressor in multi-step tumorigenesis. To establish the role of PTEN in gastric cancer progression, we examined the PTEN expression degree in gastric cancer tissues. We also explained the connection between PTEN expression and histopathological findings. Materials and methods: Our study was cross-sectional and made up of 50 patients with known gastric cancer. Immunohistochemical staining for PTEN was done on gastric cancer tissues. Tumour behaviour was estimated by histopathological assessments. Results: Twenty-seven (54%) of the 50 patients had PTEN staining. The evaluation of the connection between PTEN expression and demographic data and tumour behaviours revealed no meaningful relationship between PTEN expression and patients’ age, gender, tumour site and size, tumour type, tumour grade and stage, neural, and lymphovascular invasion (P-value > 0.05). Conclusion: PTEN expression level is expected to be a significant molecular event in the progression of gastric cancer and may be a predictive marker for gastric cancer behaviours dependent on society. © 2023 Sociedad Espanola de Anatomia Patologica

Style	Citing Format
MLA	Miratashi Yazdi SA, et al.. "Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]." Revista Espanola de Patologia, vol. 57, no. 1, 2024, pp. 3-8.
APA	Miratashi Yazdi SA, Hoseini F, Eftekhar Javadi A, Nazar E (2024). Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]. Revista Espanola de Patologia, 57(1), 3-8.
Chicago	Miratashi Yazdi SA, Hoseini F, Eftekhar Javadi A, Nazar E. "Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]." Revista Espanola de Patologia 57, no. 1 (2024): 3-8.
Harvard	Miratashi Yazdi SA et al. (2024) 'Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]', Revista Espanola de Patologia, 57(1), pp. 3-8.
Vancouver	Miratashi Yazdi SA, Hoseini F, Eftekhar Javadi A, Nazar E. Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]. Revista Espanola de Patologia. 2024;57(1):3-8.
BibTex	@article{ author = {Miratashi Yazdi SA and Hoseini F and Eftekhar Javadi A and Nazar E}, title = {Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]}, journal = {Revista Espanola de Patologia}, volume = {57}, number = {1}, pages = {3-8}, year = {2024} }
RIS	TY - JOUR AU - Miratashi Yazdi SA AU - Hoseini F AU - Eftekhar Javadi A AU - Nazar E TI - Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos] JO - Revista Espanola de Patologia VL - 57 IS - 1 SP - 3 EP - 8 PY - 2024 ER -

Style

Citing Format

MLA

Miratashi Yazdi SA, et al.. "Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]." Revista Espanola de Patologia, vol. 57, no. 1, 2024, pp. 3-8.

APA

Miratashi Yazdi SA, Hoseini F, Eftekhar Javadi A, Nazar E (2024). Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]. Revista Espanola de Patologia, 57(1), 3-8.

Chicago

Miratashi Yazdi SA, Hoseini F, Eftekhar Javadi A, Nazar E. "Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]." Revista Espanola de Patologia 57, no. 1 (2024): 3-8.

Harvard

Miratashi Yazdi SA et al. (2024) 'Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]', Revista Espanola de Patologia, 57(1), pp. 3-8.

Vancouver

Miratashi Yazdi SA, Hoseini F, Eftekhar Javadi A, Nazar E. Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]. Revista Espanola de Patologia. 2024;57(1):3-8.

BibTex

@article{ author = {Miratashi Yazdi SA and Hoseini F and Eftekhar Javadi A and Nazar E}, title = {Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]}, journal = {Revista Espanola de Patologia}, volume = {57}, number = {1}, pages = {3-8}, year = {2024} }

RIS

TY - JOUR
AU - Miratashi Yazdi SA
AU - Hoseini F
AU - Eftekhar Javadi A
AU - Nazar E
TI - Evaluation of Phosphatase and Tensin Homologue (Pten) Expression in Gastric Cancer and Its Relationship With Histopathological Findings; [Evaluacion De La Expresion Del Homologo De Fosfatasa Y Tensina (Pten) En El Cancer Gastrico Y Su Relacion Con Los Hallazgos Histopatologicos]
JO - Revista Espanola de Patologia
VL - 57
IS - 1
SP - 3
EP - 8
PY - 2024
ER -

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