Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment

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Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment Publisher

Maali A^{1, 2} ; Sarfi M^{3, 4} ; Mirzakhani M^{1, 5} ; Goodarzi G^{3, 4, 8} ; Maghsoudi H¹ ; Maniati M⁶ ; Tehrani SS^{3, 4} ; Qujeq D⁷

Show Affiliations

1. Student Research Committee, Babol University of Medical Sciences, Babol, Iran
2. Student Research Committee, Pasteur Institute of Iran, Tehran, Iran
3. Department of Clinical Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Student Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
5. Immunoregulation Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
6. Department of English, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
7. Department of Clinical Biochemistry, Babol University of Medical Sciences, Babol, Iran
8. Department of Clinical Biochemistry, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran

Source: Current Chemical Biology Published:2020

Abstract

Tumor cell growth and survival are the outcomes of communication between tumor cells and tumor microenvironment (TME). In other words, tumor cell growth and survival are greatly affected by the interaction between adjacent cells and tumor cells. In this paper, we review the recent advances in studies of TME, including metabolic interplays between tumor cells and their non-malignant neighbors (peaceful interaction and autophagy), trades of signaling pathways (approach to most important ones; cytokine pathway, NF-kB pathway, intra-tumoral hypoxia, oxidative stress, and nitric oxide-depended pathways), miRNAs (as the regulatory molecules which are present in TME), and Tumor-associated Exosomes (TAEs). Characterization of TME bio-molecules, nutrient changes, and cellular and molecular interactions help to clarify the progression of cancer and find novel targets for the treatment of cancer. © 2020 Bentham Science Publishers.

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Style	Citing Format
MLA	Maali A, et al.. "Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment." Current Chemical Biology, vol. 14, no. 4, 2020, pp. 228-239.
APA	Maali A, Sarfi M, Mirzakhani M, Goodarzi G, Maghsoudi H, Maniati M, Tehrani SS, Qujeq D (2020). Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment. Current Chemical Biology, 14(4), 228-239.
Chicago	Maali A, Sarfi M, Mirzakhani M, Goodarzi G, Maghsoudi H, Maniati M, Tehrani SS, Qujeq D. "Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment." Current Chemical Biology 14, no. 4 (2020): 228-239.
Harvard	Maali A et al. (2020) 'Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment', Current Chemical Biology, 14(4), pp. 228-239.
Vancouver	Maali A, Sarfi M, Mirzakhani M, Goodarzi G, Maghsoudi H, Maniati M, et al.. Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment. Current Chemical Biology. 2020;14(4):228-239.
BibTex	@article{ author = {Maali A and Sarfi M and Mirzakhani M and Goodarzi G and Maghsoudi H and Maniati M and Tehrani SS and Qujeq D}, title = {Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment}, journal = {Current Chemical Biology}, volume = {14}, number = {4}, pages = {228-239}, year = {2020} }
RIS	TY - JOUR AU - Maali A AU - Sarfi M AU - Mirzakhani M AU - Goodarzi G AU - Maghsoudi H AU - Maniati M AU - Tehrani SS AU - Qujeq D TI - Peaceful Existence of Tumor Cells With Their Non-Malignant Neighbors: The Trade of Tumor Cells With Tumor Micro-Environment JO - Current Chemical Biology VL - 14 IS - 4 SP - 228 EP - 239 PY - 2020 ER -

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