The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage

The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage Publisher Pubmed

Gorabi AM¹ ; Kiaie N¹ ; Hajighasemi S² ; Jamialahmadi T^{3, 4} ; Majeed M⁵ ; Sahebkar A^{6, 7, 8}

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1. Research Center for Advanced Technologies in Cardiovascular Medicine, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, 1411713138, Iran
2. Department of Medical Biotechnology, Faculty of Paramedicine, Qazvin University of Medical Sciences, Qazvin, 15315-34199, Iran
3. Halal Research Center of IRI, FDA, Tehran, Iran
4. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5. Sabinsa Corporation, East Windsor, 08520, NJ, United States
6. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
7. University OfWestern Australia, Perth, 6009, Australia
8. Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Molecules Published:2019

Abstract

Curcumin has been placed at the forefront of the researcher's attention due to its pleiotropic pharmacological effects and health benefits. A considerable volume of articles has pointed out curcumin's effects on the fate of stem cell differentiation. In this review, a descriptive mechanism of how curcumin affects the outcome of the differentiation of mesenchymal stem cells (MSCs) into the mesodermal lineage-i.e., adipocyte, osteocyte, and chondrocyte differentiation-is compiled from the literature. The sections include the mechanism of inhibition or induction of MSCs differentiation to each lineage, their governing molecular mechanisms, and their signal transduction pathways. The effect of different curcumin doses and its structural modifications on the MSCs differentiation is also discussed. © 2019 by the authors.

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Style	Citing Format
MLA	Gorabi AM, et al.. "The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage." Molecules, vol. 24, no. 22, 2019, pp. -.
APA	Gorabi AM, Kiaie N, Hajighasemi S, Jamialahmadi T, Majeed M, Sahebkar A (2019). The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage. Molecules, 24(22), -.
Chicago	Gorabi AM, Kiaie N, Hajighasemi S, Jamialahmadi T, Majeed M, Sahebkar A. "The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage." Molecules 24, no. 22 (2019): -.
Harvard	Gorabi AM et al. (2019) 'The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage', Molecules, 24(22), pp. -.
Vancouver	Gorabi AM, Kiaie N, Hajighasemi S, Jamialahmadi T, Majeed M, Sahebkar A. The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage. Molecules. 2019;24(22):-.
BibTex	@article{ author = {Gorabi AM and Kiaie N and Hajighasemi S and Jamialahmadi T and Majeed M and Sahebkar A}, title = {The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage}, journal = {Molecules}, volume = {24}, number = {22}, pages = {-}, year = {2019} }
RIS	TY - JOUR AU - Gorabi AM AU - Kiaie N AU - Hajighasemi S AU - Jamialahmadi T AU - Majeed M AU - Sahebkar A TI - The Effect of Curcumin on the Differentiation of Mesenchymal Stem Cells Into Mesodermal Lineage JO - Molecules VL - 24 IS - 22 SP - EP - PY - 2019 ER -

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