Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers

Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers Publisher Pubmed

Akbari A¹ ; Sedaghat M² ; Heshmati J³ ; Tabaeian SP^{1, 4} ; Dehghani S⁵ ; Pizarro AB⁶ ; Rostami Z⁷ ; Agah S¹

Show Affiliations

1. Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran
2. Department of Internal Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3. Songhor Healthcare Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
4. Department of Internal Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5. Radiation Sciences Department, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
6. Clinical Research Center, Fundacion Valle del Lili, Cali, Colombia
7. Department of Genetics, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran

Source: Biomedicine and Pharmacotherapy Published:2021

Abstract

Curcumin is a bioactive ingredient found in the Rhizomes of Curcuma longa. Curcumin is well known for its chemopreventive and anti-cancer properties. Recent findings have demonstrated several pharmacological and biological impacts of curcumin, related to the control and the management of gastrointestinal cancers. Mechanistically, curcumin exerts its biological impacts via antioxidant and anti-inflammatory effects through the interaction with various transcription factors and signaling molecules. Moreover, epigenetic modulators such as microRNAs (miRNAs) have been revealed as novel targets of curcumin. Curcumin was discovered to regulate the expression of numerous pathogenic miRNAs in gastric, colorectal, esophageal and liver cancers. The present systematic review was performed to identify miRNAs that are modulated by curcumin in gastrointestinal cancers. © 2021

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Style	Citing Format
MLA	Akbari A, et al.. "Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers." Biomedicine and Pharmacotherapy, vol. 141, no. , 2021, pp. -.
APA	Akbari A, Sedaghat M, Heshmati J, Tabaeian SP, Dehghani S, Pizarro AB, Rostami Z, Agah S (2021). Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers. Biomedicine and Pharmacotherapy, 141(), -.
Chicago	Akbari A, Sedaghat M, Heshmati J, Tabaeian SP, Dehghani S, Pizarro AB, Rostami Z, Agah S. "Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers." Biomedicine and Pharmacotherapy 141, no. (2021): -.
Harvard	Akbari A et al. (2021) 'Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers', Biomedicine and Pharmacotherapy, 141(), pp. -.
Vancouver	Akbari A, Sedaghat M, Heshmati J, Tabaeian SP, Dehghani S, Pizarro AB, et al.. Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers. Biomedicine and Pharmacotherapy. 2021;141():-.
BibTex	@article{ author = {Akbari A and Sedaghat M and Heshmati J and Tabaeian SP and Dehghani S and Pizarro AB and Rostami Z and Agah S}, title = {Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers}, journal = {Biomedicine and Pharmacotherapy}, volume = {141}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Akbari A AU - Sedaghat M AU - Heshmati J AU - Tabaeian SP AU - Dehghani S AU - Pizarro AB AU - Rostami Z AU - Agah S TI - Molecular Mechanisms Underlying Curcumin-Mediated Microrna Regulation in Carcinogenesis; Focused on Gastrointestinal Cancers JO - Biomedicine and Pharmacotherapy VL - 141 IS - SP - EP - PY - 2021 ER -

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