Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Burden of Knee Osteoarthritis in the Middle East and North Africa (Mena): An Epidemiological Analysis From 1990 to 2019 Publisher Pubmed



Hoveidaei AH1 ; Nakhostinansari A1 ; Chalian M2 ; Roshanshad A3, 4 ; Khonji MS5 ; Mashhadiagha A3, 4 ; Pooyan A2 ; Citak M6
Authors
Show Affiliations
Authors Affiliations
  1. 1. Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Radiology, Division of Musculoskeletal Imaging and Intervention, University of Washington, Seattle, WA, United States
  3. 3. Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
  5. 5. Bone and Joint Reconstruction Research Center, Iran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Orthopaedic Surgery, ENDO-Klinik Hamburg, Holstenstrasse 2, Hamburg, 22767, Germany

Source: Archives of Orthopaedic and Trauma Surgery Published:2023


Abstract

Background: Knee is the most affected joint in osteoarthritis (OA) and accounts for almost four-fifths of the burden of OA globally. We aimed to explore the prevalence, incidence, trends, and burden of knee OA during 1990–2019 in the Middle East and North Africa (MENA) region, using the Global Burden of Disease (GBD) study data. Methods: This is an epidemiological study based on the GBD data from 1990 to 2019 on knee OA in MENA countries. The prevalence, incidence, and years lived with disability (YLD) numbers of knee OA were obtained for both genders. Similarly, age-standardized rates of these indexes per 100,000 people and the proportion of total YLD caused by knee OA in each country and for the MENA region were evaluated. Results: The prevalence of knee osteoarthritis in the MENA region increased 2.88-fold, from 6.16 million cases to 17.75 million, between 1990 and 2019. Furthermore, in 2019, knee osteoarthritis accounted for approximately 1.69 million (95% UI 1.46–1.95) incident cases in MENA. The age-standardized prevalence was higher in women between 1990 (3.94% [95% UI 3.39–4.55] in women and 3.24% [95% UI 2.79–3.72] in men) and 2019 (4.44% [95% UI 3.83–5.10] in women and 3.66% [3.14–4.21] in men). Total YLDs due to knee osteoarthritis increased by more than 2.88-fold, rising from 196.29 thousand [95% UI 97.17–399.29] in 1990 to 564.66 thousand [95% UI 275.06–1,150.68] in 2019. In the year 2019, Kuwait, Turkey, and Oman had the highest age-standardized prevalence (4.42% [95% UI 3.79–5.08]), YLD (132.41 [95% UI 65.79–267.56] per 100 000), and increase (21.17%) in YLD compared with 1990 in MENA region, respectively. Conclusion: The prevalence of and YLDs due to knee OA in MENA has escalated over the last three decades. Considering the expanding burden of knee OA in MENA, policymakers should be more concerned to implement preventive strategies. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Related Docs
View other Related Docs
1. Increasing Burden of Hip Osteoarthritis in the Middle East and North Africa (Mena): An Epidemiological Analysis From 1990 to 2019, Archives of Orthopaedic and Trauma Surgery (2023)
2. Burden of Hand Osteoarthritis in the Middle East and North Africa (Mena): An Epidemiological Analysis From 1990 to 2019, Journal of Hand Surgery (2023)
3. Increasing Burden of Lower-Extremity Fractures in the Middle East and North Africa (Mena) a 30-Year Epidemiological Analysis, Journal of Bone and Joint Surgery (2024)
4. Injury Burden in Individuals Aged 50 Years or Older in the Eastern Mediterranean Region, 1990–2019: A Systematic Analysis From the Global Burden of Disease Study 2019, The Lancet Healthy Longevity (2022)
5. Estimating Mortality and Disability in Peru Before the Covid-19 Pandemic: A Systematic Analysis From the Global Burden of the Disease Study 2019, Frontiers in Public Health (2023)
6. Burden of Stroke in North Africa and Middle East, 1990 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019, BMC Neurology (2022)
7. Estimation of the Global Prevalence of Dementia in 2019 and Forecasted Prevalence in 2050: An Analysis for the Global Burden of Disease Study 2019, The Lancet Public Health (2022)
8. Epidemiology, Burden, and Attributable Risks of Infective Endocarditis in Iran and Its Provinces: From 1990 to 2019, International Journal of Cardiology (2022)
Experts (# of related papers)
View all Related Experts
Farshad Farzadfar (32)
Mohammad Ali Mansournia (29)
Other Related Docs
9. The Association Between Healthy Beverage Index and Psychological Disorders Among Overweight and Obese Women: A Cross-Sectional Study, BMC Women's Health (2022)
10. Burden of Osteoarthritis in Iran: A National and Subnational Perspective, 1990−2019 Global Burden of Disease Study, Health Science Reports (2025)
11. Burden of Ischemic Heart Disease in the Middle East and North Africa (Mena) and Attributable Risk Factors: An Epidemiological Analysis From 1990 to 2019, IJC Heart and Vasculature (2024)
12. Burden of Ischemic Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019, European Journal of Preventive Cardiology (2022)
13. National, Sub-National, and Risk-Attributed Burden of Thyroid Cancer in Iran From 1990 to 2019, Scientific Reports (2022)
14. Global Age-Sex-Specific Fertility, Mortality, Healthy Life Expectancy (Hale), and Population Estimates in 204 Countries and Territories, 1950–2019: A Comprehensive Demographic Analysis for the Global Burden of Disease Study 2019, The Lancet (2020)
15. Spatial, Temporal, and Demographic Patterns in Prevalence of Smoking Tobacco Use and Attributable Disease Burden in 204 Countries and Territories, 1990A€“2019: A Systematic Analysis From the Global Burden of Disease Study 2019, The Lancet (2021)
16. The Burden of Gout and Its Attributable Risk Factors in the Middle East and North Africa Region, 1990 to 2019, Journal of Rheumatology (2023)
17. Burden of Chronic Obstructive Pulmonary Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019: Results From the Global Burden of Disease Study 2019, The BMJ (2022)
18. Burden of Tension-Type Headache in the Middle East and North Africa Region, 1990-2019, Journal of Headache and Pain (2022)
19. Global Burden of 288 Causes of Death and Life Expectancy Decomposition in 204 Countries and Territories and 811 Subnational Locations, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
20. Trends and Levels of the Global, Regional, and National Burden of Appendicitis Between 1990 and 2021: Findings From the Global Burden of Disease Study 2021, The Lancet Gastroenterology and Hepatology (2024)
21. Prevalence, Years Lived With Disability, and Trends in Anaemia Burden by Severity and Cause, 1990–2021: Findings From the Global Burden of Disease Study 2021, The Lancet Haematology (2023)
22. Estimating the Burden of Atrial Fibrillation and Atrial Flutter With Projection to 2050 in Iran, Scientific Reports (2024)
23. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the Gbd 2019 Study, Journal of the American College of Cardiology (2020)
24. Global, Regional, and National Burden of Migraine in 204 Countries and Territories, 1990 to 2019, Pain (2022)
25. Global, Regional, and National Progress Towards Sustainable Development Goal 3.2 for Neonatal and Child Health: All-Cause and Cause-Specific Mortality Findings From the Global Burden of Disease Study 2019, The Lancet (2021)
26. Prevalence, Deaths, and Disability-Adjusted Life Years Due to Musculoskeletal Disorders for 195 Countries and Territories 1990–2017, Arthritis and Rheumatology (2021)
27. Global, Regional, and National Cancer Deaths and Disability-Adjusted Life-Years (Dalys) Attributable to Alcohol Consumption in 204 Countries and Territories, 1990-2019, Cancer (2022)
28. Global Burden of Lower Respiratory Infections During the Last Three Decades, Frontiers in Public Health (2023)
29. Burden of Cancers Attributable to High Fasting Plasma Glucose in the Middle East and North Africa Region, 1990–2019, Cancer Medicine (2023)
30. Burden of Tracheal, Bronchus, and Lung Cancer and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019, Journal of Thoracic Oncology (2021)
31. Burden of Disease Scenarios for 204 Countries and Territories, 2022–2050: A Forecasting Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
32. Global, Regional, and National Burden of Upper Respiratory Infections and Otitis Media, 1990–2021: A Systematic Analysis From the Global Burden of Disease Study 2021, The Lancet Infectious Diseases (2025)
33. The Association of Socioeconomic Status With Hypertension in 76 Low- and Middle-Income Countries, Journal of the American College of Cardiology (2022)
34. Burden and Epidemiology of Mental Disorders in the Middle East and North Africa From 1990 to 2019: Findings From the Global Burden of Disease Study, Balkan Medical Journal (2024)
35. Global, Regional, and National Burden of Allergic Disorders and Their Risk Factors in 204 Countries and Territories, From 1990 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019, Allergy: European Journal of Allergy and Clinical Immunology (2023)
36. Burden of Ischemic and Hemorrhagic Stroke Across the Us From 1990 to 2019, JAMA Neurology (2024)
37. Global, Regional and National Burden of Osteoarthritis 1990-2017: A Systematic Analysis of the Global Burden of Disease Study 2017, Annals of the Rheumatic Diseases (2020)
38. The State of Health in the European Union (Eu-27) in 2019: A Systematic Analysis for the Global Burden of Disease Study 2019, BMC Public Health (2024)
39. Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 a Systematic Analysis for the Global Burden of Disease Study 2019, JAMA Oncology (2022)
40. Age–Sex Differences in the Global Burden of Lower Respiratory Infections and Risk Factors, 1990–2019: Results From the Global Burden of Disease Study 2019, The Lancet Infectious Diseases (2022)
41. Particulate Matter Pollution Remains a Threat for Cardiovascular Health: Findings From the Global Burden of Disease 2019, Journal of the American Heart Association (2023)
42. Mortality and Disability-Adjusted Life Years in North Africa and Middle East Attributed to Kidney Dysfunction: A Systematic Analysis for the Global Burden of Disease Study 2019, Clinical Kidney Journal (2024)
43. Measuring Routine Childhood Vaccination Coverage in 204 Countries and Territories, 1980–2019: A Systematic Analysis for the Global Burden of Disease Study 2020, Release 1, The Lancet (2021)
44. Regional Burden of Chronic Kidney Disease in North Africa and Middle East During 1990–2019; Results From Global Burden of Disease Study 2019, Frontiers in Public Health (2022)
45. The Unfinished Agenda of Communicable Diseases Among Children and Adolescents Before the Covid-19 Pandemic, 1990–2019: A Systematic Analysis of the Global Burden of Disease Study 2019, The Lancet (2023)
46. Fatal Police Violence by Race and State in the Usa, 1980–2019: A Network Meta-Regression, The Lancet (2021)
47. Global, Regional, and National Sex-Specific Burden and Control of the Hiv Epidemic, 1990–2019, for 204 Countries and Territories: The Global Burden of Diseases Study 2019, The Lancet HIV (2021)
48. Incident Type 2 Diabetes Attributable to Suboptimal Diet in 184 Countries, Nature Medicine (2023)
49. Adolescent Transport and Unintentional Injuries: A Systematic Analysis Using the Global Burden of Disease Study 2019, The Lancet Public Health (2022)
50. The Burden of Diseases, Injuries, and Risk Factors by State in the Usa, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)